AutismKB 2.0

Annotation Detail for MAST4


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Basic Information Top
Gene Symbol:MAST4 ( DKFZp686E18148,DKFZp686N1467,FLJ16540,FLJ33039,KIAA0303 )
Gene Full Name: microtubule associated serine/threonine kinase family member 4
Band: 5q12.3
Quick LinksEntrez ID:375449; OMIM: NA; Uniprot ID:MAST4_HUMAN; ENSEMBL ID: ENSG00000069020; HGNC ID: 19037
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus46 / 56401281
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult120 / 193912161
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma4 / 17475228
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor2 / 17290115
gastrointestinal tumor5 / 11936941
germ cell tumor6 / 26384522
glioma2 / 10688318
head and neck tumor10 / 13630273
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor8 / 10312777
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal190 / 336030756
ovarian tumor1 / 7668213
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites1 / 4001524
bladder2 / 2975767
blood4 / 12347832
bone2 / 7165527
bone marrow0 / 488010 
brain37 / 110098933
cervix1 / 4817120
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus2 / 2020998
eye7 / 21105433
heart10 / 89626111
intestine4 / 23447217
kidney6 / 21177728
larynx3 / 24145124
liver4 / 20774319
lung23 / 33697468
lymph0 / 442700 
lymph node8 / 9161087
mammary gland4 / 15327126
mouth8 / 67052119
muscle6 / 10771555
nerve0 / 157680 
ovary1 / 1020519
pancreas23 / 214812107
parathyroid0 / 205390 
pharynx7 / 41328169
pituitary gland0 / 165850 
placenta23 / 28082581
prostate6 / 18934531
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach4 / 9661941
testis5 / 33044215
thymus4 / 8113149
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus19 / 23287881
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210958_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.5
Adipocyte14.45
AdrenalCortex17.95
Adrenalgland17.85
Amygdala15.9
Appendix14.6
AtrioventricularNode10.65
BDCA4+_DentriticCells4.9
Bonemarrow14.3
BronchialEpithelialCells16.2
CD105+_Endothelial12.75
CD14+_Monocytes4.3
CD19+_BCells(neg._sel.)10
CD33+_Myeloid8.15
CD34+17.05
CD4+_Tcells16.3
CD56+_NKCells8.85
CD71+_EarlyErythroid9.75
CD8+_Tcells13.15
CardiacMyocytes18.1
Caudatenucleus13.2
Cerebellum11.95
CerebellumPeduncles16.55
CiliaryGanglion9.9
CingulateCortex29.15
Colorectaladenocarcinoma14.4
DorsalRootGanglion10.8
FetalThyroid14.25
Fetalbrain14.9
Fetalliver12.35
Fetallung12.85
GlobusPallidus10.5
Heart19
Hypothalamus15.45
Kidney14.35
Leukemia_chronicMyelogenousK-56213.3
Leukemia_promyelocytic-HL-6010.85
Leukemialymphoblastic(MOLT-4)11.5
Liver18.9
Lung16.5
Lymphnode12.85
Lymphoma_burkitts(Daudi)18.6
Lymphoma_burkitts(Raji)20.25
MedullaOblongata21.1
OccipitalLobe14.2
OlfactoryBulb11.65
Ovary9.55
Pancreas11.7
PancreaticIslet23.95
ParietalLobe27.6
Pituitary17.25
Placenta16.8
Pons20
PrefrontalCortex34
Prostate37.95
Salivarygland12
SkeletalMuscle20.7
Skin10.9
SmoothMuscle14.3
Spinalcord15.7
SubthalamicNucleus15.35
SuperiorCervicalGanglion17.9
TemporalLobe14.25
Testis12.9
TestisGermCell13.4
TestisIntersitial12.35
TestisLeydigCell16.45
TestisSeminiferousTubule13.95
Thalamus14.6
Thymus17.65
Thyroid17.4
Tongue24.05
Tonsil19.55
Trachea12.5
TrigeminalGanglion15
Uterus19.5
UterusCorpus13.6
WholeBlood15.3
Wholebrain14.7
colon14.6
pineal_day15.34
pineal_night14.26
retina19.025
small_intestine14
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P349783
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.73 ± 0.61
Basal Forebrain5.37 ± 0.18
Basal Part of Pons5.37 ± 0.25
Cerebellar Cortex4.84 ± 0.25
Cerebellar Nuclei5.56 ± 0.35
Claustrum5.05 ± 0.44
Epithalamus4.96 ± 0.25
Frontal Lobe5.22 ± 0.35
Globus Pallidus5.99 ± 0.26
Hypothalamus5.13 ± 0.35
Insula4.8 ± 0.4
Limbic Lobe5.09 ± 0.37
Mesencephalon5.24 ± 0.39
Myelencephalon5.08 ± 0.47
Occipital Lobe4.8 ± 0.42
Parietal Lobe5.13 ± 0.35
Pontine Tegmentum5.06 ± 0.4
Striatum5.26 ± 0.37
Subthalamus5.18 ± 0.59
Temporal Lobe5 ± 0.36
Thalamus5.05 ± 0.36
White Matter6.42 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mast4CBCerebellum15.32
19.71
Mast4CTXCerebral cortex3.99
2.96
Mast4HIPHippocampal region8.51
8.64
Mast4HPFHippocampal formation7.93
7.26
Mast4HYHypothalamus1.26
1.39
Mast4LSXLateral septal complex0.46
0.4
Mast4MBMidbrain2.86
3
Mast4MYMedulla11.18
11.86
Mast4OLFOlfactory bulb6
4.78
Mast4PPons6.38
6.77
Mast4PALPallidum0.63
0.6
Mast4RHPRetrohippocampal region7.84
6.01
Mast4sAMYStriatum-like amygdalar nuclei0.28
0.25
Mast4STRStriatum0.89
0.82
Mast4STRdStriatum dorsal region1.05
0.97
Mast4STRvStriatum ventral region0.73
0.53
Mast4THThalamus3.16
2.7
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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