Annotation Detail for AGRN
Basic Information Top
| Gene Symbol: | AGRN ( FLJ45064 ) |
|---|---|
| Gene Full Name: | agrin |
| Band: | 1p36.33 |
| Quick Links | Entrez ID:375790; OMIM: 103320; Uniprot ID:AGRIN_HUMAN; ENSEMBL ID: ENSG00000188157; HGNC ID: 329 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.273330
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 38 / 70761 | 537 |  |
| blastocyst | 18 / 62319 | 288 | |
| fetus | 44 / 564012 | 78 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 3 / 55556 | 53 | |
| adult | 167 / 1939121 | 86 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 5 / 94178 | 53 | |
| cervical tumor | 3 / 34366 | 87 | |
| chondrosarcoma | 17 / 82823 | 205 | |
| colorectal tumor | 24 / 114246 | 210 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 31 / 119369 | 259 | |
| germ cell tumor | 33 / 263845 | 125 | |
| glioma | 20 / 106883 | 187 | |
| head and neck tumor | 3 / 136302 | 22 |  |
| kidney tumor | 23 / 68959 | 333 | |
| leukemia | 1 / 95842 | 10 |  |
| liver tumor | 10 / 96359 | 103 | |
| lung tumor | 13 / 103127 | 126 | |
| lymphoma | 2 / 71755 | 27 | |
| non-neoplasia | 9 / 97250 | 92 | |
| normal | 244 / 3360307 | 72 | |
| ovarian tumor | 13 / 76682 | 169 | |
| pancreatic tumor | 18 / 104616 | 172 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 33 / 102680 | 321 | |
| retinoblastoma | 5 / 46356 | 107 | |
| skin tumor | 5 / 124949 | 40 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 20 / 90257 | 221 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 17 / 40015 | 424 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 7 / 71655 | 97 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 47 / 1100989 | 42 | |
| cervix | 4 / 48171 | 83 | |
| connective tissue | 9 / 149255 | 60 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 67 / 215722 | 310 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 37 / 211054 | 175 | |
| heart | 5 / 89626 | 55 | |
| intestine | 37 / 234472 | 157 | |
| kidney | 30 / 211777 | 141 | |
| larynx | 1 / 24145 | 41 | |
| liver | 11 / 207743 | 52 | |
| lung | 44 / 336974 | 130 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 11 / 153271 | 71 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 40 / 102051 | 391 | |
| pancreas | 20 / 214812 | 93 | |
| parathyroid | 2 / 20539 | 97 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 11 / 280825 | 39 | |
| prostate | 40 / 189345 | 211 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 27 / 210574 | 128 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 13 / 96619 | 134 | |
| testis | 3 / 330442 | 9 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 3 / 47473 | 63 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 27 / 232878 | 115 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 212283_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 3.85 | |
| Adipocyte | 2.95 | |
| AdrenalCortex | 3.35 | |
| Adrenalgland | 2.55 | |
| Amygdala | 3.25 | |
| Appendix | 3.25 | |
| AtrioventricularNode | 2.25 | |
| BDCA4+_DentriticCells | 3.4 | |
| Bonemarrow | 3.55 | |
| BronchialEpithelialCells | 3.5 | |
| CD105+_Endothelial | 3.05 | |
| CD14+_Monocytes | 3.2 | |
| CD19+_BCells(neg._sel.) | 3.25 | |
| CD33+_Myeloid | 3.9 | |
| CD34+ | 3.85 | |
| CD4+_Tcells | 3.35 | |
| CD56+_NKCells | 3.65 | |
| CD71+_EarlyErythroid | 2.9 | |
| CD8+_Tcells | 2.95 | |
| CardiacMyocytes | 3.75 | |
| Caudatenucleus | 2.7 | |
| Cerebellum | 2.45 | |
| CerebellumPeduncles | 3.4 | |
| CiliaryGanglion | 2.05 | |
| CingulateCortex | 3.05 | |
| Colorectaladenocarcinoma | 3.05 | |
| DorsalRootGanglion | 2.25 | |
| FetalThyroid | 3 | |
| Fetalbrain | 3.05 | |
| Fetalliver | 2.55 | |
| Fetallung | 2.55 | |
| GlobusPallidus | 2.15 | |
| Heart | 3.75 | |
| Hypothalamus | 3.35 | |
| Kidney | 2.4 | |
| Leukemia_chronicMyelogenousK-562 | 2.75 | |
| Leukemia_promyelocytic-HL-60 | 2.65 | |
| Leukemialymphoblastic(MOLT-4) | 2.45 | |
| Liver | 3.95 | |
| Lung | 3.4 | |
| Lymphnode | 2.65 | |
| Lymphoma_burkitts(Daudi) | 3.85 | |
| Lymphoma_burkitts(Raji) | 4.2 | |
| MedullaOblongata | 3.1 | |
| OccipitalLobe | 2.85 | |
| OlfactoryBulb | 2.4 | |
| Ovary | 1.95 | |
| Pancreas | 2.5 | |
| PancreaticIslet | 3.25 | |
| ParietalLobe | 3.15 | |
| Pituitary | 3.65 | |
| Placenta | 3.15 | |
| Pons | 2.85 | |
| PrefrontalCortex | 3.8 | |
| Prostate | 3.6 | |
| Salivarygland | 2.5 | |
| SkeletalMuscle | 4.6 | |
| Skin | 2.25 | |
| SmoothMuscle | 3.6 | |
| Spinalcord | 3.25 | |
| SubthalamicNucleus | 2.7 | |
| SuperiorCervicalGanglion | 4.15 | |
| TemporalLobe | 2.75 | |
| Testis | 2.6 | |
| TestisGermCell | 2.55 | |
| TestisIntersitial | 2.45 | |
| TestisLeydigCell | 3 | |
| TestisSeminiferousTubule | 2.6 | |
| Thalamus | 3.1 | |
| Thymus | 2.45 | |
| Thyroid | 3.8 | |
| Tongue | 2.95 | |
| Tonsil | 2.95 | |
| Trachea | 2.55 | |
| TrigeminalGanglion | 2.95 | |
| Uterus | 2.5 | |
| UterusCorpus | 2.65 | |
| WholeBlood | 3.35 | |
| Wholebrain | 2.6 | |
| colon | 3.05 | |
| pineal_day | 3.78 | |
| pineal_night | 3.7 | |
| retina | 3.675 | |
| small_intestine | 2.9 | |
- Probe name: CUST_72_PI416408490
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.19 ± 0.95 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.7 ± 0.33 | |
| Basal Part of Pons | 3.7 ± 1.38 | |
| Cerebellar Cortex | 2.82 ± 0.56 | |
| Cerebellar Nuclei | 3.39 ± 0.64 | |
| Claustrum | 4.5 ± 0.57 | |
| Epithalamus | 3.6 ± 0.7 | |
| Frontal Lobe | 3.27 ± 0.77 | |
| Globus Pallidus | 4.08 ± 0.64 | |
| Hypothalamus | 3.14 ± 0.82 | |
| Insula | 3.41 ± 0.65 | |
| Limbic Lobe | 3.36 ± 0.83 | |
| Mesencephalon | 3.58 ± 0.75 | |
| Myelencephalon | 3.47 ± 0.77 | |
| Occipital Lobe | 3.81 ± 0.75 | |
| Parietal Lobe | 3.57 ± 0.8 | |
| Pontine Tegmentum | 3.43 ± 0.65 | |
| Striatum | 3.57 ± 0.85 | |
| Subthalamus | 2.99 ± 0.75 | |
| Temporal Lobe | 3.43 ± 0.76 | |
| Thalamus | 3.28 ± 0.7 | |
| White Matter | 3.99 ± 1.14 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Agrin | CB | Cerebellum | 6.03 | |
| 6.13 | | |||
| Agrin | CTX | Cerebral cortex | 42.95 | |
| 31.16 | | |||
| Agrin | HIP | Hippocampal region | 31.56 | |
| 48.97 | | |||
| Agrin | HPF | Hippocampal formation | 32.57 | |
| 37.19 | | |||
| Agrin | HY | Hypothalamus | 25.08 | |
| 17.74 | | |||
| Agrin | LSX | Lateral septal complex | 39.04 | |
| 28.23 | | |||
| Agrin | MB | Midbrain | 32.05 | |
| 26.84 | | |||
| Agrin | MY | Medulla | 35.89 | |
| 34.35 | | |||
| Agrin | OLF | Olfactory bulb | 45.03 | |
| 36.45 | | |||
| Agrin | P | Pons | 28 | |
| 25.29 | | |||
| Agrin | PAL | Pallidum | 17.96 | |
| 13.19 | | |||
| Agrin | RHP | Retrohippocampal region | 33.89 | |
| 26.79 | | |||
| Agrin | sAMY | Striatum-like amygdalar nuclei | 26.81 | |
| 18.49 | | |||
| Agrin | STR | Striatum | 16.97 | |
| 11.75 | | |||
| Agrin | STRd | Striatum dorsal region | 10.52 | |
| 7.31 | | |||
| Agrin | STRv | Striatum ventral region | 24.1 | |
| 15.4 | | |||
| Agrin | TH | Thalamus | 49.65 | |
| 38.3 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00009377 | 11 | 2008 | 2018 | AYGTGFVGCLR | Peptide Atlas |