AutismKB 2.0

Annotation Detail for KCNJ16


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:KCNJ16 ( BIR9,KIR5.1,MGC33717 )
Gene Full Name: potassium inwardly-rectifying channel, subfamily J, member 16
Band: 17q24.3
Quick LinksEntrez ID:3773; OMIM: 605722; Uniprot ID:IRK16_HUMAN; ENSEMBL ID: ENSG00000153822; HGNC ID: 6262
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult40 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor0 / 2638450 
glioma10 / 10688393
head and neck tumor9 / 13630266
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal82 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain38 / 110098934
cervix0 / 481710 
connective tissue0 / 1492550 
ear1 / 1621261
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney39 / 211777184
larynx0 / 241450 
liver1 / 2077434
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve2 / 15768126
ovary0 / 1020510 
pancreas9 / 21481241
parathyroid23 / 205391119
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach3 / 9661931
testis1 / 3304423
thymus0 / 811310 
thyroid10 / 47473210
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219564_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.5
Adipocyte4.55
AdrenalCortex5.3
Adrenalgland4.1
Amygdala5.1
Appendix5.15
AtrioventricularNode3.95
BDCA4+_DentriticCells4.9
Bonemarrow4.65
BronchialEpithelialCells4.5
CD105+_Endothelial4.6
CD14+_Monocytes4.9
CD19+_BCells(neg._sel.)4.85
CD33+_Myeloid5.85
CD34+5.8
CD4+_Tcells4.85
CD56+_NKCells5.3
CD71+_EarlyErythroid4.45
CD8+_Tcells4.4
CardiacMyocytes6.5
Caudatenucleus4.25
Cerebellum35.7
CerebellumPeduncles9.2
CiliaryGanglion3.55
CingulateCortex15.3
Colorectaladenocarcinoma4.7
DorsalRootGanglion3.85
FetalThyroid413.85
Fetalbrain4.6
Fetalliver4.05
Fetallung3.75
GlobusPallidus3.55
Heart6.45
Hypothalamus55.1
Kidney222.8
Leukemia_chronicMyelogenousK-5624.2
Leukemia_promyelocytic-HL-604.15
Leukemialymphoblastic(MOLT-4)3.65
Liver6.55
Lung5.15
Lymphnode3.9
Lymphoma_burkitts(Daudi)6
Lymphoma_burkitts(Raji)6.6
MedullaOblongata4.25
OccipitalLobe4.35
OlfactoryBulb3.65
Ovary3.2
Pancreas9.9
PancreaticIslet113.55
ParietalLobe5.1
Pituitary5.5
Placenta4.65
Pons4.55
PrefrontalCortex11.6
Prostate5.4
Salivarygland3.8
SkeletalMuscle6.1
Skin3.9
SmoothMuscle5.2
Spinalcord23.7
SubthalamicNucleus4.35
SuperiorCervicalGanglion6.65
TemporalLobe4.4
Testis3.9
TestisGermCell4
TestisIntersitial3.9
TestisLeydigCell4.7
TestisSeminiferousTubule4
Thalamus5.45
Thymus3.55
Thyroid1209.15
Tongue4.7
Tonsil4.5
Trachea3.85
TrigeminalGanglion6.4
Uterus3.75
UterusCorpus4.4
WholeBlood5.1
Wholebrain4.3
colon4.7
pineal_day8.02
pineal_night5.92
retina8.675
small_intestine4.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13853_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.77 ± 1.42
Basal Forebrain3.53 ± 0.42
Basal Part of Pons3.17 ± 1.05
Cerebellar Cortex3.24 ± 0.96
Cerebellar Nuclei4.62 ± 1.23
Claustrum4.02 ± 0.92
Epithalamus3.01 ± 0.77
Frontal Lobe3.27 ± 1.01
Globus Pallidus3.64 ± 0.67
Hypothalamus3.25 ± 0.65
Insula3.37 ± 0.96
Limbic Lobe3.47 ± 0.93
Mesencephalon3.65 ± 0.93
Myelencephalon3.45 ± 0.88
Occipital Lobe3.57 ± 0.92
Parietal Lobe3.28 ± 0.96
Pontine Tegmentum3.35 ± 0.97
Striatum3.45 ± 0.88
Subthalamus3.57 ± 0.5
Temporal Lobe3.24 ± 1.01
Thalamus3.22 ± 0.82
White Matter3.78 ± 0.49
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Kcnj16CBCerebellum1.7
1.47
Kcnj16CTXCerebral cortex0.53
0.35
Kcnj16HIPHippocampal region0.61
0.35
Kcnj16HPFHippocampal formation0.9
0.69
Kcnj16HYHypothalamus0.44
0.26
Kcnj16LSXLateral septal complex0.06
0.14
Kcnj16MBMidbrain0.52
0.51
Kcnj16MYMedulla1.73
1.51
Kcnj16OLFOlfactory bulb1.82
1.17
Kcnj16PPons1.85
1.3
Kcnj16PALPallidum0.59
0.41
Kcnj16RHPRetrohippocampal region1.34
1.09
Kcnj16sAMYStriatum-like amygdalar nuclei2.49
1.63
Kcnj16STRStriatum0.53
0.34
Kcnj16STRdStriatum dorsal region0.08
0.05
Kcnj16STRvStriatum ventral region1.31
0.71
Kcnj16THThalamus0.53
0.36
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved