AutismKB 2.0

Annotation Detail for KCNK3


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Basic Information Top
Gene Symbol:KCNK3 ( K2p3.1,OAT1,TASK,TASK-1,TBAK1 )
Gene Full Name: potassium channel, subfamily K, member 3
Band: 2p23.3
Quick LinksEntrez ID:3777; OMIM: 603220; Uniprot ID:KCNK3_HUMAN; ENSEMBL ID: ENSG00000171303; HGNC ID: 6278
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant2 / 2362084
juvenile0 / 555560 
adult40 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor9 / 12794703
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma3 / 10688328
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal75 / 336030722
ovarian tumor5 / 7668265
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma5 / 46356107
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland11 / 33197331
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain18 / 110098916
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye8 / 21105437
heart0 / 896260 
intestine0 / 2344720 
kidney8 / 21177737
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary5 / 10205148
pancreas30 / 214812139
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta18 / 28082564
prostate1 / 1893455
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205952_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.75
Adipocyte61.5
AdrenalCortex726
Adrenalgland757.15
Amygdala16.35
Appendix25.9
AtrioventricularNode5.75
BDCA4+_DentriticCells6.95
Bonemarrow7.3
BronchialEpithelialCells6.85
CD105+_Endothelial7
CD14+_Monocytes7.45
CD19+_BCells(neg._sel.)7.25
CD33+_Myeloid8.5
CD34+8.3
CD4+_Tcells7.1
CD56+_NKCells7.8
CD71+_EarlyErythroid6.6
CD8+_Tcells6.25
CardiacMyocytes10
Caudatenucleus6.5
Cerebellum37.4
CerebellumPeduncles26.7
CiliaryGanglion5.3
CingulateCortex16.45
Colorectaladenocarcinoma7
DorsalRootGanglion5.8
FetalThyroid7.1
Fetalbrain6.9
Fetalliver6.25
Fetallung68.05
GlobusPallidus5.4
Heart17.35
Hypothalamus9.9
Kidney6.75
Leukemia_chronicMyelogenousK-5626.35
Leukemia_promyelocytic-HL-606.3
Leukemialymphoblastic(MOLT-4)5.45
Liver10.95
Lung183.35
Lymphnode5.95
Lymphoma_burkitts(Daudi)9.25
Lymphoma_burkitts(Raji)10.5
MedullaOblongata8.85
OccipitalLobe8.75
OlfactoryBulb5.45
Ovary11.75
Pancreas10.35
PancreaticIslet110.05
ParietalLobe8.6
Pituitary8.8
Placenta102.85
Pons8.45
PrefrontalCortex16.95
Prostate12
Salivarygland5.9
SkeletalMuscle10.8
Skin5.65
SmoothMuscle7.95
Spinalcord7.55
SubthalamicNucleus6.55
SuperiorCervicalGanglion9.65
TemporalLobe11.45
Testis6.15
TestisGermCell5.95
TestisIntersitial5.9
TestisLeydigCell15.15
TestisSeminiferousTubule6.2
Thalamus20.15
Thymus5.35
Thyroid11.1
Tongue7.4
Tonsil7.05
Trachea5.95
TrigeminalGanglion8
Uterus5.6
UterusCorpus13.55
WholeBlood7.75
Wholebrain19.05
colon7.3
pineal_day587.48
pineal_night520.24
retina8.85
small_intestine9.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P388190
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.61 ± 0.76
Basal Forebrain2.99 ± 0.72
Basal Part of Pons3.23 ± 0.73
Cerebellar Cortex3.6 ± 0.68
Cerebellar Nuclei3.45 ± 0.7
Claustrum3.82 ± 0.7
Epithalamus2.99 ± 0.63
Frontal Lobe3.26 ± 0.72
Globus Pallidus3.62 ± 1.17
Hypothalamus3.16 ± 0.61
Insula3.03 ± 1.04
Limbic Lobe3.45 ± 0.83
Mesencephalon3.27 ± 0.77
Myelencephalon3.36 ± 0.7
Occipital Lobe3.68 ± 0.69
Parietal Lobe3.28 ± 0.73
Pontine Tegmentum3.34 ± 0.84
Striatum3.07 ± 0.76
Subthalamus3.2 ± 0.82
Temporal Lobe3.23 ± 0.8
Thalamus3.18 ± 0.67
White Matter3.08 ± 0.76
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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