AutismKB 2.0

Annotation Detail for KCNMB1


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Basic Information Top
Gene Symbol:KCNMB1 ( K(VCA)beta,SLO-BETA,hslo-beta )
Gene Full Name: potassium large conductance calcium-activated channel, subfamily M, beta member 1
Band: 5q35.1
Quick LinksEntrez ID:3779; OMIM: 603951; Uniprot ID:KCMB1_HUMAN; ENSEMBL ID: ENSG00000145936; HGNC ID: 6285
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus11 / 56401219
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult27 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal44 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow0 / 488010 
brain3 / 11009892
cervix1 / 4817120
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart2 / 8962622
intestine8 / 23447234
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate4 / 18934521
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus14 / 23287860
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209948_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.65
Adipocyte3.7
AdrenalCortex3.85
Adrenalgland3.25
Amygdala4.1
Appendix27.05
AtrioventricularNode3.55
BDCA4+_DentriticCells5.75
Bonemarrow4
BronchialEpithelialCells3.45
CD105+_Endothelial3.65
CD14+_Monocytes4.1
CD19+_BCells(neg._sel.)3.85
CD33+_Myeloid5.05
CD34+4.85
CD4+_Tcells4.1
CD56+_NKCells4.5
CD71+_EarlyErythroid3.6
CD8+_Tcells3.6
CardiacMyocytes4.55
Caudatenucleus3.4
Cerebellum3.35
CerebellumPeduncles4.3
CiliaryGanglion2.65
CingulateCortex3.9
Colorectaladenocarcinoma3.8
DorsalRootGanglion3
FetalThyroid3.65
Fetalbrain3.8
Fetalliver4.25
Fetallung3.2
GlobusPallidus2.8
Heart4.75
Hypothalamus4.15
Kidney3.1
Leukemia_chronicMyelogenousK-5623.45
Leukemia_promyelocytic-HL-603.35
Leukemialymphoblastic(MOLT-4)3.05
Liver5.1
Lung4.15
Lymphnode3.55
Lymphoma_burkitts(Daudi)4.85
Lymphoma_burkitts(Raji)5.5
MedullaOblongata3.5
OccipitalLobe3.35
OlfactoryBulb3.05
Ovary3.4
Pancreas3.05
PancreaticIslet4.05
ParietalLobe3.9
Pituitary6.6
Placenta4
Pons3.6
PrefrontalCortex4.7
Prostate85.75
Salivarygland2.95
SkeletalMuscle4.6
Skin2.9
SmoothMuscle4.1
Spinalcord4.9
SubthalamicNucleus3.45
SuperiorCervicalGanglion6.8
TemporalLobe3.45
Testis3.45
TestisGermCell10.8
TestisIntersitial3.35
TestisLeydigCell4.15
TestisSeminiferousTubule4.8
Thalamus3.85
Thymus3
Thyroid4.8
Tongue3.65
Tonsil3.7
Trachea16.35
TrigeminalGanglion3.65
Uterus233.45
UterusCorpus106.35
WholeBlood4.25
Wholebrain3.25
colon64.8
pineal_day4.9
pineal_night4.52
retina19.575
small_intestine36.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P206121
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.25 ± 0.63
Basal Forebrain5.77 ± 0.47
Basal Part of Pons6.36 ± 0.49
Cerebellar Cortex5.82 ± 0.64
Cerebellar Nuclei6.12 ± 0.49
Claustrum6.49 ± 0.55
Epithalamus5.5 ± 0.38
Frontal Lobe6.07 ± 0.56
Globus Pallidus6.42 ± 0.56
Hypothalamus5.67 ± 0.78
Insula6 ± 0.65
Limbic Lobe6.14 ± 0.55
Mesencephalon5.88 ± 0.44
Myelencephalon6.03 ± 0.59
Occipital Lobe5.91 ± 0.55
Parietal Lobe5.99 ± 0.51
Pontine Tegmentum5.86 ± 0.61
Striatum6.01 ± 0.56
Subthalamus6.26 ± 0.16
Temporal Lobe5.94 ± 0.66
Thalamus6.04 ± 0.45
White Matter5.58 ± 0.27
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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