AutismKB 2.0

Annotation Detail for KCNS3


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Basic Information Top
Gene Symbol:KCNS3 ( KV9.3,MGC9481 )
Gene Full Name: potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
Band: 2p24.2
Quick LinksEntrez ID:3790; OMIM: 603888; Uniprot ID:KCNS3_HUMAN; ENSEMBL ID: ENSG00000170745; HGNC ID: 6302
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus9 / 56401215
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult36 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor7 / 68959101
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal50 / 336030714
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor9 / 12494972
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain9 / 11009898
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye4 / 21105418
heart6 / 8962666
intestine5 / 23447221
kidney9 / 21177742
larynx0 / 241450 
liver2 / 2077439
lung10 / 33697429
lymph0 / 442700 
lymph node4 / 9161043
mammary gland8 / 15327152
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate3 / 18934515
salivary gland0 / 201550 
skin10 / 21057447
spleen0 / 539520 
stomach5 / 9661951
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205968_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.95
Adipocyte5.9
AdrenalCortex6.5
Adrenalgland5.05
Amygdala5.8
Appendix7.2
AtrioventricularNode5.05
BDCA4+_DentriticCells6.15
Bonemarrow6.05
BronchialEpithelialCells5.55
CD105+_Endothelial6
CD14+_Monocytes6.2
CD19+_BCells(neg._sel.)6.25
CD33+_Myeloid7.4
CD34+7.45
CD4+_Tcells6.25
CD56+_NKCells6.8
CD71+_EarlyErythroid5.65
CD8+_Tcells5.45
CardiacMyocytes8.05
Caudatenucleus5.3
Cerebellum4.8
CerebellumPeduncles6.8
CiliaryGanglion4.8
CingulateCortex6.15
Colorectaladenocarcinoma5.95
DorsalRootGanglion4.85
FetalThyroid5.9
Fetalbrain5.8
Fetalliver5.1
Fetallung5.05
GlobusPallidus5.25
Heart7.85
Hypothalamus6.45
Kidney4.9
Leukemia_chronicMyelogenousK-5625.3
Leukemia_promyelocytic-HL-605.25
Leukemialymphoblastic(MOLT-4)4.6
Liver7.8
Lung50.85
Lymphnode4.95
Lymphoma_burkitts(Daudi)7.6
Lymphoma_burkitts(Raji)8.3
MedullaOblongata5.5
OccipitalLobe5.35
OlfactoryBulb7.85
Ovary3.95
Pancreas4.8
PancreaticIslet6.4
ParietalLobe6.35
Pituitary6.9
Placenta6.15
Pons5.65
PrefrontalCortex7.15
Prostate6.75
Salivarygland4.85
SkeletalMuscle7.4
Skin5.45
SmoothMuscle6.6
Spinalcord6.45
SubthalamicNucleus5.95
SuperiorCervicalGanglion7.55
TemporalLobe5.45
Testis5.1
TestisGermCell5
TestisIntersitial5
TestisLeydigCell5.9
TestisSeminiferousTubule5.1
Thalamus6.1
Thymus4.45
Thyroid7.15
Tongue5.95
Tonsil5.75
Trachea5
TrigeminalGanglion10.25
Uterus4.75
UterusCorpus5.65
WholeBlood6.25
Wholebrain5.05
colon6.1
pineal_day7.5
pineal_night7.2
retina7.65
small_intestine8.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6474_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.7 ± 0.96
Basal Forebrain2.08 ± 0.24
Basal Part of Pons2.65 ± 0.56
Cerebellar Cortex1.99 ± 0.62
Cerebellar Nuclei2.56 ± 0.65
Claustrum3 ± 0.65
Epithalamus1.98 ± 0.77
Frontal Lobe2.35 ± 0.74
Globus Pallidus2.55 ± 0.43
Hypothalamus2.35 ± 0.56
Insula1.94 ± 0.53
Limbic Lobe2.41 ± 0.68
Mesencephalon2.52 ± 0.67
Myelencephalon2.35 ± 0.66
Occipital Lobe2.33 ± 0.6
Parietal Lobe2.47 ± 0.78
Pontine Tegmentum2.28 ± 0.71
Striatum2.38 ± 0.74
Subthalamus2.49 ± 0.74
Temporal Lobe2.24 ± 0.67
Thalamus2.21 ± 0.65
White Matter3.6 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Kcns3CBCerebellum6.3
8.41
Kcns3CTXCerebral cortex14.44
12.5
Kcns3HIPHippocampal region13.1
16.4
Kcns3HPFHippocampal formation13.17
14.22
Kcns3HYHypothalamus3.11
4.16
Kcns3LSXLateral septal complex0.73
0.58
Kcns3MBMidbrain6.02
8.61
Kcns3MYMedulla13.06
16.59
Kcns3OLFOlfactory bulb4.24
4.69
Kcns3PPons7.86
10.7
Kcns3PALPallidum3.05
3.59
Kcns3RHPRetrohippocampal region13.63
11.57
Kcns3sAMYStriatum-like amygdalar nuclei1.26
1.3
Kcns3STRStriatum2.34
2.18
Kcns3STRdStriatum dorsal region2.34
2.24
Kcns3STRvStriatum ventral region3.32
2.73
Kcns3THThalamus5.15
7.12
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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