AutismKB 2.0

Annotation Detail for KIF2A


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Basic Information Top
Gene Symbol:KIF2A ( HK2,KIF2 )
Gene Full Name: kinesin heavy chain member 2A
Band: 5q12.1
Quick LinksEntrez ID:3796; OMIM: 602591; Uniprot ID:KIF2A_HUMAN; ENSEMBL ID: ENSG00000068796; HGNC ID: 6318
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst6 / 6231996
fetus50 / 56401288
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult76 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor5 / 11424643
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor22 / 26384583
glioma4 / 10688337
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia11 / 95842114
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal200 / 336030759
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor7 / 12494956
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder1 / 2975733
blood8 / 12347864
bone4 / 7165555
bone marrow5 / 48801102
brain78 / 110098970
cervix2 / 4817141
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus1 / 2020949
eye7 / 21105433
heart3 / 8962633
intestine10 / 23447242
kidney9 / 21177742
larynx0 / 241450 
liver8 / 20774338
lung5 / 33697414
lymph0 / 442700 
lymph node19 / 91610207
mammary gland3 / 15327119
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta14 / 28082549
prostate3 / 18934515
salivary gland1 / 2015549
skin7 / 21057433
spleen1 / 5395218
stomach4 / 9661941
testis32 / 33044296
thymus8 / 8113198
thyroid1 / 4747321
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord1 / 1368073
uterus9 / 23287838
vascular4 / 5178077
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P254091
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.45 ± 0.31
Basal Forebrain9.67 ± 0.14
Basal Part of Pons9.77 ± 0.2
Cerebellar Cortex9.38 ± 0.14
Cerebellar Nuclei9.73 ± 0.15
Claustrum9.65 ± 0.24
Epithalamus9.92 ± 0.18
Frontal Lobe9.77 ± 0.22
Globus Pallidus9.87 ± 0.23
Hypothalamus9.84 ± 0.25
Insula9.71 ± 0.18
Limbic Lobe9.67 ± 0.29
Mesencephalon9.69 ± 0.31
Myelencephalon9.64 ± 0.3
Occipital Lobe9.37 ± 0.32
Parietal Lobe9.6 ± 0.21
Pontine Tegmentum9.65 ± 0.25
Striatum9.47 ± 0.33
Subthalamus9.84 ± 0.26
Temporal Lobe9.73 ± 0.23
Thalamus9.65 ± 0.25
White Matter10.57 ± 0.05
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Kif2aCBCerebellum45.53
92.74
Kif2aCTXCerebral cortex100
100
Kif2aHIPHippocampal region100
100
Kif2aHPFHippocampal formation100
100
Kif2aHYHypothalamus100
100
Kif2aLSXLateral septal complex100
100
Kif2aMBMidbrain100
100
Kif2aMYMedulla96.59
100
Kif2aOLFOlfactory bulb100
100
Kif2aPPons95.01
100
Kif2aPALPallidum96.24
100
Kif2aRHPRetrohippocampal region100
100
Kif2asAMYStriatum-like amygdalar nuclei100
100
Kif2aSTRStriatum100
92.91
Kif2aSTRdStriatum dorsal region90.25
79.86
Kif2aSTRvStriatum ventral region100
93.49
Kif2aTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
KIF2A_HUMAN_26 35 26 60 EIDLESIFSLNPDLVPDEEIEPSPETPPPPASSAK PRIDE
KIF2A_HUMAN_269 9 269 277 PLVETIFER PRIDE
KIF2A_HUMAN_603 8 603 610 AVFQESIR PRIDE
KIF2A_HUMAN_91 29 91 119 ARPSQFPEQSSSAQQNGSVSDISPVQAAK PRIDE
PAp00009307 18 185 202 AQDVDATNPNYEIMCMIR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018