AutismKB 2.0

Annotation Detail for KRAS


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Basic Information Top
Gene Symbol:KRAS ( C-K-RAS,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KI-RAS,KRAS1,KRAS2,NS,NS3,RASK2 )
Gene Full Name: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Band: 12p12.1
Quick LinksEntrez ID:3845; OMIM: 190070; Uniprot ID:RASK_HUMAN; ENSEMBL ID: ENSG00000133703; HGNC ID: 6407
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body12 / 70761169
blastocyst5 / 6231980
fetus34 / 56401260
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult150 / 193912177
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor3 / 3436687
chondrosarcoma5 / 8282360
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor26 / 26384598
glioma1 / 1068839
head and neck tumor33 / 136302242
kidney tumor2 / 6895929
leukemia8 / 9584283
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma3 / 7175541
non-neoplasia5 / 9725051
normal182 / 336030754
ovarian tumor23 / 76682299
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor9 / 12494972
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder2 / 2975767
blood8 / 12347864
bone3 / 7165541
bone marrow6 / 48801122
brain36 / 110098932
cervix3 / 4817162
connective tissue7 / 14925546
ear2 / 16212123
embryonic tissue23 / 215722106
esophagus0 / 202090 
eye5 / 21105423
heart7 / 8962678
intestine13 / 23447255
kidney7 / 21177733
larynx1 / 2414541
liver2 / 2077439
lung11 / 33697432
lymph1 / 4427022
lymph node29 / 91610316
mammary gland20 / 153271130
mouth4 / 6705259
muscle4 / 10771537
nerve1 / 1576863
ovary23 / 102051225
pancreas6 / 21481227
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta23 / 28082581
prostate5 / 18934526
salivary gland0 / 201550 
skin16 / 21057475
spleen1 / 5395218
stomach3 / 9661931
testis22 / 33044266
thymus3 / 8113136
thyroid29 / 47473610
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus9 / 23287838
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214352_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts338.7
Adipocyte21.95
AdrenalCortex12.55
Adrenalgland21.55
Amygdala266.5
Appendix24.85
AtrioventricularNode12.6
BDCA4+_DentriticCells131.7
Bonemarrow46.55
BronchialEpithelialCells38.05
CD105+_Endothelial277.6
CD14+_Monocytes217.5
CD19+_BCells(neg._sel.)157.65
CD33+_Myeloid497.15
CD34+197.4
CD4+_Tcells173.55
CD56+_NKCells558.45
CD71+_EarlyErythroid70.9
CD8+_Tcells210.7
CardiacMyocytes49.05
Caudatenucleus13.45
Cerebellum115.6
CerebellumPeduncles84.75
CiliaryGanglion16.35
CingulateCortex63.7
Colorectaladenocarcinoma139.65
DorsalRootGanglion36.45
FetalThyroid39.75
Fetalbrain73.45
Fetalliver66.75
Fetallung39.85
GlobusPallidus31.7
Heart15.05
Hypothalamus35.4
Kidney17.2
Leukemia_chronicMyelogenousK-56218.15
Leukemia_promyelocytic-HL-6045.95
Leukemialymphoblastic(MOLT-4)96.6
Liver10.7
Lung59.5
Lymphnode21.05
Lymphoma_burkitts(Daudi)15
Lymphoma_burkitts(Raji)73.35
MedullaOblongata41.8
OccipitalLobe103.3
OlfactoryBulb137.9
Ovary10
Pancreas61
PancreaticIslet36.2
ParietalLobe51.25
Pituitary33.35
Placenta50.15
Pons27.5
PrefrontalCortex155.45
Prostate201.15
Salivarygland8.45
SkeletalMuscle8.7
Skin17.55
SmoothMuscle58.1
Spinalcord8.45
SubthalamicNucleus56.75
SuperiorCervicalGanglion21.8
TemporalLobe57.7
Testis23.7
TestisGermCell26.3
TestisIntersitial20.65
TestisLeydigCell11.7
TestisSeminiferousTubule14
Thalamus8.9
Thymus178.2
Thyroid26.35
Tongue34.8
Tonsil44.35
Trachea60.35
TrigeminalGanglion15.6
Uterus105.7
UterusCorpus14.85
WholeBlood114.65
Wholebrain182
colon408.25
pineal_day190.92
pineal_night169.6
retina36.875
small_intestine143.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P45140
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.81 ± 0.52
Basal Forebrain7.92 ± 0.28
Basal Part of Pons8.28 ± 0.32
Cerebellar Cortex8.32 ± 0.09
Cerebellar Nuclei7.63 ± 0.37
Claustrum8.05 ± 0.48
Epithalamus8.14 ± 0.3
Frontal Lobe8.21 ± 0.27
Globus Pallidus7.1 ± 0.24
Hypothalamus8.43 ± 0.24
Insula8.31 ± 0.27
Limbic Lobe7.95 ± 0.5
Mesencephalon8.02 ± 0.43
Myelencephalon7.96 ± 0.45
Occipital Lobe7.64 ± 0.51
Parietal Lobe8.1 ± 0.32
Pontine Tegmentum7.99 ± 0.41
Striatum7.2 ± 0.41
Subthalamus8.23 ± 0.36
Temporal Lobe8.19 ± 0.26
Thalamus8.06 ± 0.31
White Matter6.88 ± 0.05
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
KrasCBCerebellum0.07
0.34
KrasCTXCerebral cortex12.58
12.54
KrasHIPHippocampal region18.17
26.1
KrasHPFHippocampal formation16.88
22.1
KrasHYHypothalamus2.76
3.03
KrasLSXLateral septal complex4.36
5.89
KrasMBMidbrain0.52
1.04
KrasMYMedulla0.26
0.7
KrasOLFOlfactory bulb13.74
13.6
KrasPPons1.02
2.45
KrasPALPallidum3.28
4.4
KrasRHPRetrohippocampal region15.05
16.62
KrassAMYStriatum-like amygdalar nuclei17.8
15.54
KrasSTRStriatum3.19
3.12
KrasSTRdStriatum dorsal region0.98
0.98
KrasSTRvStriatum ventral region1.77
1.75
KrasTHThalamus2.32
2.79
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00006948 26 17 42 SALTIQLIQNHFVDEYDPTIEDSYRK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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