Annotation Detail for KRT7
Basic Information Top
| Gene Symbol: | KRT7 ( CK7,K2C7,K7,MGC129731,MGC3625,SCL ) |
|---|---|
| Gene Full Name: | keratin 7 |
| Band: | 12q13.13 |
| Quick Links | Entrez ID:3855; OMIM: 148059; Uniprot ID:K2C7_HUMAN; ENSEMBL ID: ENSG00000135480; HGNC ID: 6445 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.670221
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 25 / 70761 | 353 |  |
| blastocyst | 1 / 62319 | 16 |  |
| fetus | 14 / 564012 | 24 | |
| neonate | 3 / 31097 | 96 |  |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 739 / 1939121 | 381 | |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 0 / 564012 | 0 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 12 / 1939121 | 6 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 98 / 17475 | 5608 |  |
| breast (mammary gland) tumor | 21 / 94178 | 222 | |
| cervical tumor | 51 / 34366 | 1484 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 17 / 114246 | 148 | |
| esophageal tumor | 6 / 17290 | 347 | |
| gastrointestinal tumor | 22 / 119369 | 184 | |
| germ cell tumor | 13 / 263845 | 49 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 110 / 136302 | 807 | |
| kidney tumor | 4 / 68959 | 58 | |
| leukemia | 5 / 95842 | 52 | |
| liver tumor | 24 / 96359 | 249 | |
| lung tumor | 138 / 103127 | 1338 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 5 / 97250 | 51 | |
| normal | 505 / 3360307 | 150 | |
| ovarian tumor | 74 / 76682 | 965 | |
| pancreatic tumor | 93 / 104616 | 888 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 31 / 102680 | 301 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 130 / 90257 | 1440 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 6 / 3360307 | 1 |  |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 4 / 90257 | 44 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 111 / 29757 | 3730 | |
| blood | 3 / 123478 | 24 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 8 / 1100989 | 7 | |
| cervix | 51 / 48171 | 1058 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 27 / 215722 | 125 | |
| esophagus | 6 / 20209 | 296 | |
| eye | 9 / 211054 | 42 | |
| heart | 0 / 89626 | 0 | |
| intestine | 17 / 234472 | 72 | |
| kidney | 108 / 211777 | 509 | |
| larynx | 2 / 24145 | 82 | |
| liver | 26 / 207743 | 125 | |
| lung | 196 / 336974 | 581 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 100 / 153271 | 652 | |
| mouth | 7 / 67052 | 104 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 75 / 102051 | 734 | |
| pancreas | 110 / 214812 | 512 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 2 / 16585 | 120 | |
| placenta | 230 / 280825 | 819 | |
| prostate | 50 / 189345 | 264 | |
| salivary gland | 9 / 20155 | 446 | |
| skin | 8 / 210574 | 37 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 27 / 96619 | 279 | |
| testis | 1 / 330442 | 3 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 111 / 47473 | 2338 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 17 / 52413 | 324 | |
| umbilical cord | 4 / 13680 | 292 | |
| uterus | 158 / 232878 | 678 | |
| vascular | 14 / 51780 | 270 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 1 / 1100989 | 0 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 2 / 234472 | 8 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 4 / 336974 | 11 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 3 / 91610 | 32 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 0 / 330442 | 0 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 209016_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 6 | |
| Adipocyte | 4.15 | |
| AdrenalCortex | 4.5 | |
| Adrenalgland | 3.5 | |
| Amygdala | 4.3 | |
| Appendix | 4.25 | |
| AtrioventricularNode | 3.25 | |
| BDCA4+_DentriticCells | 4.5 | |
| Bonemarrow | 4.1 | |
| BronchialEpithelialCells | 1227.3 | |
| CD105+_Endothelial | 4.15 | |
| CD14+_Monocytes | 4.4 | |
| CD19+_BCells(neg._sel.) | 4.45 | |
| CD33+_Myeloid | 5.3 | |
| CD34+ | 5.2 | |
| CD4+_Tcells | 4.45 | |
| CD56+_NKCells | 4.95 | |
| CD71+_EarlyErythroid | 3.9 | |
| CD8+_Tcells | 3.95 | |
| CardiacMyocytes | 128.45 | |
| Caudatenucleus | 3.7 | |
| Cerebellum | 3.35 | |
| CerebellumPeduncles | 4.75 | |
| CiliaryGanglion | 3.05 | |
| CingulateCortex | 4.4 | |
| Colorectaladenocarcinoma | 5.85 | |
| DorsalRootGanglion | 3.2 | |
| FetalThyroid | 443.1 | |
| Fetalbrain | 4.05 | |
| Fetalliver | 3.6 | |
| Fetallung | 250 | |
| GlobusPallidus | 3.15 | |
| Heart | 5.4 | |
| Hypothalamus | 4.5 | |
| Kidney | 5.7 | |
| Leukemia_chronicMyelogenousK-562 | 3.75 | |
| Leukemia_promyelocytic-HL-60 | 3.7 | |
| Leukemialymphoblastic(MOLT-4) | 3.35 | |
| Liver | 5.5 | |
| Lung | 432.45 | |
| Lymphnode | 3.65 | |
| Lymphoma_burkitts(Daudi) | 5.35 | |
| Lymphoma_burkitts(Raji) | 5.9 | |
| MedullaOblongata | 3.8 | |
| OccipitalLobe | 3.7 | |
| OlfactoryBulb | 3.25 | |
| Ovary | 2.75 | |
| Pancreas | 5.25 | |
| PancreaticIslet | 48.45 | |
| ParietalLobe | 4.4 | |
| Pituitary | 4.85 | |
| Placenta | 737.5 | |
| Pons | 3.95 | |
| PrefrontalCortex | 5.1 | |
| Prostate | 50.65 | |
| Salivarygland | 63.6 | |
| SkeletalMuscle | 5.6 | |
| Skin | 8.35 | |
| SmoothMuscle | 174.8 | |
| Spinalcord | 4.4 | |
| SubthalamicNucleus | 3.8 | |
| SuperiorCervicalGanglion | 4.8 | |
| TemporalLobe | 3.8 | |
| Testis | 3.5 | |
| TestisGermCell | 3.45 | |
| TestisIntersitial | 3.45 | |
| TestisLeydigCell | 4.1 | |
| TestisSeminiferousTubule | 3.55 | |
| Thalamus | 4.25 | |
| Thymus | 3.25 | |
| Thyroid | 2912.75 | |
| Tongue | 4.2 | |
| Tonsil | 4.15 | |
| Trachea | 39.65 | |
| TrigeminalGanglion | 4.25 | |
| Uterus | 3.4 | |
| UterusCorpus | 4 | |
| WholeBlood | 4.45 | |
| Wholebrain | 3.45 | |
| colon | 4.15 | |
| pineal_day | 5.16 | |
| pineal_night | 5.04 | |
| retina | 5 | |
| small_intestine | 3.95 | |
- Probe name: CUST_15915_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.42 ± 1.1 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.78 ± 0.55 | |
| Basal Part of Pons | 2.76 ± 0.64 | |
| Cerebellar Cortex | 2.4 ± 0.59 | |
| Cerebellar Nuclei | 3.1 ± 0.5 | |
| Claustrum | 3.47 ± 0.69 | |
| Epithalamus | 3.61 ± 0.34 | |
| Frontal Lobe | 2.81 ± 0.76 | |
| Globus Pallidus | 3.6 ± 0.62 | |
| Hypothalamus | 2.51 ± 0.99 | |
| Insula | 2.46 ± 0.7 | |
| Limbic Lobe | 2.98 ± 0.81 | |
| Mesencephalon | 3.04 ± 0.73 | |
| Myelencephalon | 3.02 ± 0.76 | |
| Occipital Lobe | 3.16 ± 0.69 | |
| Parietal Lobe | 2.94 ± 0.84 | |
| Pontine Tegmentum | 2.88 ± 0.73 | |
| Striatum | 3.76 ± 0.74 | |
| Subthalamus | 2.71 ± 0.69 | |
| Temporal Lobe | 2.79 ± 0.82 | |
| Thalamus | 2.69 ± 0.69 | |
| White Matter | 3.74 ± 0.45 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Krt7 | CB | Cerebellum | 0.38 | |
| 0.73 | | |||
| Krt7 | CTX | Cerebral cortex | 0.88 | |
| 0.99 | | |||
| Krt7 | HIP | Hippocampal region | 0.18 | |
| 0.49 | | |||
| Krt7 | HPF | Hippocampal formation | 0.17 | |
| 0.47 | | |||
| Krt7 | HY | Hypothalamus | 0.28 | |
| 0.41 | | |||
| Krt7 | LSX | Lateral septal complex | 0.06 | |
| 0 | | |||
| Krt7 | MB | Midbrain | 0.46 | |
| 0.94 | | |||
| Krt7 | MY | Medulla | 0.4 | |
| 0.41 | | |||
| Krt7 | OLF | Olfactory bulb | 0.77 | |
| 2.15 | | |||
| Krt7 | P | Pons | 0.45 | |
| 1.22 | | |||
| Krt7 | PAL | Pallidum | 0.16 | |
| 0.15 | | |||
| Krt7 | RHP | Retrohippocampal region | 0.15 | |
| 0.38 | | |||
| Krt7 | sAMY | Striatum-like amygdalar nuclei | 0.56 | |
| 0.57 | | |||
| Krt7 | STR | Striatum | 0.64 | |
| 0.72 | | |||
| Krt7 | STRd | Striatum dorsal region | 0.59 | |
| 0.6 | | |||
| Krt7 | STRv | Striatum ventral region | 0.26 | |
| 0.2 | | |||
| Krt7 | TH | Thalamus | 0.32 | |
| 0.4 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| K2C7_HUMAN_136 | 13 | 136 | 148 | LPDIFEAQIAGLR | PRIDE |
| K2C7_HUMAN_187 | 11 | 187 | 197 | TAAENEFVVLK | PRIDE |
| K2C7_HUMAN_214 | 12 | 214 | 225 | VDALNDEINFLR | PRIDE |
| K2C7_HUMAN_253 | 12 | 253 | 264 | SLDLDGIIAEVK | PRIDE |
| K2C7_HUMAN_276 | 10 | 276 | 285 | AEAEAWYQTK | PRIDE |
| K2C7_HUMAN_286 | 10 | 286 | 295 | FETLQAQAGK | PRIDE |
| K2C7_HUMAN_30 | 16 | 30 | 45 | PGGLGSSSLYGLGASR | PRIDE |
| K2C7_HUMAN_30 | 18 | 30 | 47 | PGGLGSSSLYGLGASRPR | PRIDE |
| K2C7_HUMAN_317 | 9 | 317 | 325 | LQAEIDNIK | PRIDE |
| K2C7_HUMAN_329 | 13 | 329 | 341 | AKLEAAIAEAEER | PRIDE |
| K2C7_HUMAN_331 | 11 | 331 | 341 | LEAAIAEAEER | PRIDE |
| K2C7_HUMAN_351 | 12 | 351 | 362 | AKQEELEAALQR | PRIDE |
| K2C7_HUMAN_52 | 12 | 52 | 63 | SAYGGPVGAGIR | PRIDE |
| K2C7_HUMAN_53 | 11 | 53 | 63 | AYGGPVGAGIR | PRIDE |
| K2C7_HUMAN_64 | 13 | 64 | 76 | EVTINQSLLAPLR | PRIDE |
| K2C7_HUMAN_77 | 9 | 77 | 85 | LDADPSLQR | PRIDE |
| K2C7_HUMAN_86 | 10 | 86 | 95 | VRQEESEQIK | PRIDE |
| PAp00032364 | 12 | 352 | 363 | AKQEELEAALQR | Peptide Atlas |