AutismKB 2.0

Annotation Detail for THEMIS


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Basic Information Top
Gene Symbol:THEMIS ( C6orf190,C6orf207,FLJ40584,GASP,MGC163388,SPOT,TSEPA,bA325O24.3,bA325O24.4 )
Gene Full Name: thymocyte selection associated
Band: 6q22.33
Quick LinksEntrez ID:387357; OMIM: 613607; Uniprot ID:THMS1_HUMAN; ENSEMBL ID: ENSG00000172673; HGNC ID: 21569
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult5 / 19391212
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal16 / 33603074
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone0 / 716550 
bone marrow0 / 488010 
brain5 / 11009894
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart2 / 8962622
intestine0 / 2344720 
kidney0 / 2117770 
larynx1 / 2414541
liver1 / 2077434
lung0 / 3369740 
lymph0 / 442700 
lymph node2 / 9161021
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen3 / 5395255
stomach0 / 966190 
testis0 / 3304420 
thymus23 / 81131283
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1248_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.7 ± 0.98
Basal Forebrain4.35 ± 0.3
Basal Part of Pons4.55 ± 0.65
Cerebellar Cortex4.24 ± 0.6
Cerebellar Nuclei4.88 ± 0.85
Claustrum8.14 ± 0.73
Epithalamus4.28 ± 0.96
Frontal Lobe5.3 ± 1.32
Globus Pallidus3.67 ± 1.79
Hypothalamus4.8 ± 0.95
Insula5.36 ± 0.46
Limbic Lobe4.99 ± 1.23
Mesencephalon5.02 ± 0.93
Myelencephalon4.94 ± 0.88
Occipital Lobe6.08 ± 0.82
Parietal Lobe5.84 ± 0.92
Pontine Tegmentum5.2 ± 1.21
Striatum2.94 ± 1.7
Subthalamus4.62 ± 0.89
Temporal Lobe5.29 ± 0.81
Thalamus4.43 ± 0.79
White Matter4.1 ± 1.87
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
E430004N04RikCBCerebellum4.79
5.09
E430004N04RikCTXCerebral cortex0.49
0.85
E430004N04RikHIPHippocampal region0.33
0.53
E430004N04RikHPFHippocampal formation0.23
0.37
E430004N04RikHYHypothalamus0.04
0.17
E430004N04RikLSXLateral septal complex0.61
0.95
E430004N04RikMBMidbrain0.1
0.19
E430004N04RikMYMedulla0.48
0.5
E430004N04RikOLFOlfactory bulb0.99
1.59
E430004N04RikPPons0.07
0.14
E430004N04RikPALPallidum0.01
0
E430004N04RikRHPRetrohippocampal region0.02
0.12
E430004N04RiksAMYStriatum-like amygdalar nuclei0
0
E430004N04RikSTRStriatum0.2
0.28
E430004N04RikSTRdStriatum dorsal region0.18
0.26
E430004N04RikSTRvStriatum ventral region0.11
0.17
E430004N04RikTHThalamus2.16
2.71
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018