AutismKB 2.0

Annotation Detail for C12orf68


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Basic Information Top
Gene Symbol:C12orf68 ( - )
Gene Full Name: chromosome 12 open reading frame 68
Band: 12q13.11
Quick LinksEntrez ID:387856; OMIM: NA; Uniprot ID:CL068_HUMAN; ENSEMBL ID: ENSG00000177875; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus50 / 56401288
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult29 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor13 / 26384549
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal111 / 336030733
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain98 / 110098989
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine1 / 2344724
kidney3 / 21177714
larynx0 / 241450 
liver1 / 2077434
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7167_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.14 ± 0.38
Basal Forebrain6.11 ± 0.51
Basal Part of Pons6.7 ± 0.33
Cerebellar Cortex6.23 ± 0.3
Cerebellar Nuclei6.05 ± 0.39
Claustrum6.13 ± 0.67
Epithalamus5.48 ± 0.55
Frontal Lobe6.24 ± 0.46
Globus Pallidus5.71 ± 0.52
Hypothalamus6 ± 0.8
Insula6.04 ± 0.47
Limbic Lobe6.37 ± 0.61
Mesencephalon6.29 ± 0.72
Myelencephalon6.24 ± 0.58
Occipital Lobe6.9 ± 0.77
Parietal Lobe6.38 ± 0.45
Pontine Tegmentum6.16 ± 0.58
Striatum5.46 ± 0.49
Subthalamus6.14 ± 0.3
Temporal Lobe6.2 ± 0.46
Thalamus6.55 ± 0.57
White Matter3.67 ± 0.85
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AI836003CBCerebellum8.13
11.33
AI836003CTXCerebral cortex29.36
23.99
AI836003HIPHippocampal region12.45
13.53
AI836003HPFHippocampal formation15.37
15.26
AI836003HYHypothalamus24.03
21.69
AI836003LSXLateral septal complex2.16
1.5
AI836003MBMidbrain34.12
36.99
AI836003MYMedulla29.94
43.78
AI836003OLFOlfactory bulb20.04
17.03
AI836003PPons36.67
46.04
AI836003PALPallidum20.71
23.58
AI836003RHPRetrohippocampal region19.53
17.14
AI836003sAMYStriatum-like amygdalar nuclei10.77
8.52
AI836003STRStriatum4.35
3.5
AI836003STRdStriatum dorsal region3.33
2.6
AI836003STRvStriatum ventral region4.96
4.04
AI836003THThalamus40.93
39.78
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018