AutismKB 2.0

Annotation Detail for NHLRC3


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Basic Information Top
Gene Symbol:NHLRC3 ( DKFZp313M1221,DKFZp686E1140 )
Gene Full Name: NHL repeat containing 3
Band: 13q13.3
Quick LinksEntrez ID:387921; OMIM: NA; Uniprot ID:NHLC3_HUMAN; ENSEMBL ID: ENSG00000188811; HGNC ID: 33751
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst4 / 6231964
fetus16 / 56401228
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult50 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor7 / 26384526
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal81 / 336030724
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain26 / 110098923
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine4 / 23447217
kidney12 / 21177756
larynx0 / 241450 
liver5 / 20774324
lung2 / 3369745
lymph1 / 4427022
lymph node1 / 9161010
mammary gland3 / 15327119
mouth2 / 6705229
muscle4 / 10771537
nerve0 / 157680 
ovary4 / 10205139
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate3 / 18934515
salivary gland0 / 201550 
skin6 / 21057428
spleen0 / 539520 
stomach0 / 966190 
testis13 / 33044239
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P418934
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.59 ± 0.47
Basal Forebrain6.85 ± 0.11
Basal Part of Pons6.65 ± 0.27
Cerebellar Cortex6.8 ± 0.15
Cerebellar Nuclei6.63 ± 0.18
Claustrum6.29 ± 0.52
Epithalamus6.85 ± 0.2
Frontal Lobe6.62 ± 0.29
Globus Pallidus7.01 ± 0.22
Hypothalamus6.88 ± 0.07
Insula6.63 ± 0.16
Limbic Lobe6.61 ± 0.34
Mesencephalon6.72 ± 0.29
Myelencephalon6.65 ± 0.29
Occipital Lobe6.82 ± 0.35
Parietal Lobe6.66 ± 0.29
Pontine Tegmentum6.74 ± 0.26
Striatum6.67 ± 0.26
Subthalamus6.23 ± 0.34
Temporal Lobe6.65 ± 0.22
Thalamus6.67 ± 0.25
White Matter8 ± 0.15
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
8030451K01RikCBCerebellum1.6
2.85
8030451K01RikCTXCerebral cortex1.39
2.04
8030451K01RikHIPHippocampal region0.54
0.89
8030451K01RikHPFHippocampal formation0.51
0.75
8030451K01RikHYHypothalamus0.3
0.35
8030451K01RikLSXLateral septal complex0.64
0.64
8030451K01RikMBMidbrain0.76
0.89
8030451K01RikMYMedulla0.87
1.11
8030451K01RikOLFOlfactory bulb1.22
2.47
8030451K01RikPPons1.61
1.49
8030451K01RikPALPallidum0.45
0.59
8030451K01RikRHPRetrohippocampal region0.45
0.52
8030451K01RiksAMYStriatum-like amygdalar nuclei0.92
1.45
8030451K01RikSTRStriatum0.52
0.69
8030451K01RikSTRdStriatum dorsal region0.53
0.77
8030451K01RikSTRvStriatum ventral region0.29
0.29
8030451K01RikTHThalamus0.86
1.08
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00432902 31 221 251 PPVGSIGECSVISTIQLADQVLPHLLEVDRK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018