AutismKB 2.0

Annotation Detail for RHOB


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Basic Information Top
Gene Symbol:RHOB ( ARH6,ARHB,MST081,MSTP081,RHOH6 )
Gene Full Name: ras homolog gene family, member B
Band: 2p24.1
Quick LinksEntrez ID:388; OMIM: 165370; Uniprot ID:RHOB_HUMAN; ENSEMBL ID: ENSG00000143878; HGNC ID: 668
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body14 / 70761197
blastocyst3 / 6231948
fetus76 / 564012134
neonate0 / 310970 
infant1 / 2362042
juvenile3 / 5555653
adult230 / 1939121118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor5 / 34366145
chondrosarcoma12 / 82823144
colorectal tumor2 / 11424617
esophageal tumor2 / 17290115
gastrointestinal tumor12 / 119369100
germ cell tumor52 / 263845197
glioma55 / 106883514
head and neck tumor2 / 13630214
kidney tumor10 / 68959145
leukemia22 / 95842229
liver tumor6 / 9635962
lung tumor9 / 10312787
lymphoma1 / 7175513
non-neoplasia17 / 97250174
normal650 / 3360307193
ovarian tumor7 / 7668291
pancreatic tumor17 / 104616162
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer6 / 10268058
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue6 / 13106457
adrenal gland10 / 33197301
ascites5 / 40015124
bladder2 / 2975767
blood3 / 12347824
bone8 / 71655111
bone marrow2 / 4880140
brain171 / 1100989155
cervix7 / 48171145
connective tissue18 / 149255120
ear1 / 1621261
embryonic tissue26 / 215722120
esophagus3 / 20209148
eye13 / 21105461
heart13 / 89626145
intestine50 / 234472213
kidney206 / 211777972
larynx0 / 241450 
liver11 / 20774352
lung47 / 336974139
lymph0 / 442700 
lymph node3 / 9161032
mammary gland24 / 153271156
mouth5 / 6705274
muscle0 / 1077150 
nerve2 / 15768126
ovary9 / 10205188
pancreas45 / 214812209
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta25 / 28082589
prostate38 / 189345200
salivary gland0 / 201550 
skin14 / 21057466
spleen2 / 5395237
stomach13 / 96619134
testis16 / 33044248
thymus4 / 8113149
thyroid0 / 474730 
tonsil0 / 169990 
trachea8 / 52413152
umbilical cord0 / 136800 
uterus31 / 232878133
vascular51 / 51780984
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212099_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.65
Adipocyte430.35
AdrenalCortex2515.45
Adrenalgland2881.8
Amygdala1493.1
Appendix389.7
AtrioventricularNode233.95
BDCA4+_DentriticCells423.8
Bonemarrow528.6
BronchialEpithelialCells47.25
CD105+_Endothelial114.7
CD14+_Monocytes1456.7
CD19+_BCells(neg._sel.)1025.35
CD33+_Myeloid808.3
CD34+16.1
CD4+_Tcells7.25
CD56+_NKCells338.5
CD71+_EarlyErythroid6.15
CD8+_Tcells9.45
CardiacMyocytes204.4
Caudatenucleus725.9
Cerebellum884.2
CerebellumPeduncles657.65
CiliaryGanglion350
CingulateCortex813
Colorectaladenocarcinoma1316.3
DorsalRootGanglion299.05
FetalThyroid163.5
Fetalbrain627.3
Fetalliver116.9
Fetallung1042
GlobusPallidus265.95
Heart712.45
Hypothalamus1040.2
Kidney393.15
Leukemia_chronicMyelogenousK-56244.75
Leukemia_promyelocytic-HL-605.6
Leukemialymphoblastic(MOLT-4)5.05
Liver1599.45
Lung2999.3
Lymphnode208.7
Lymphoma_burkitts(Daudi)7.95
Lymphoma_burkitts(Raji)9.15
MedullaOblongata608.55
OccipitalLobe889.4
OlfactoryBulb1589.2
Ovary1540.35
Pancreas266
PancreaticIslet600.9
ParietalLobe710.85
Pituitary473.25
Placenta2494.85
Pons338.15
PrefrontalCortex1940.65
Prostate1297.55
Salivarygland98.35
SkeletalMuscle101.75
Skin320.1
SmoothMuscle205.1
Spinalcord2513.6
SubthalamicNucleus490
SuperiorCervicalGanglion107.7
TemporalLobe393
Testis246.9
TestisGermCell467.8
TestisIntersitial168.05
TestisLeydigCell296.15
TestisSeminiferousTubule154.05
Thalamus1294.25
Thymus296.4
Thyroid1061.45
Tongue198.25
Tonsil16.1
Trachea915.55
TrigeminalGanglion169.55
Uterus1085.35
UterusCorpus1984.85
WholeBlood766.45
Wholebrain1248.5
colon882.85
pineal_day440.86
pineal_night425.6
retina1817.65
small_intestine579.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13512_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.9 ± 0.18
Basal Forebrain8.25 ± 0.16
Basal Part of Pons8.23 ± 0.33
Cerebellar Cortex8.11 ± 0.21
Cerebellar Nuclei8.84 ± 0.33
Claustrum8.04 ± 0.2
Epithalamus8.03 ± 0.63
Frontal Lobe8.42 ± 0.41
Globus Pallidus9.47 ± 0.36
Hypothalamus8.37 ± 0.22
Insula8.13 ± 0.32
Limbic Lobe8.15 ± 0.33
Mesencephalon8.57 ± 0.43
Myelencephalon8.42 ± 0.41
Occipital Lobe8.2 ± 0.38
Parietal Lobe8.36 ± 0.36
Pontine Tegmentum8.47 ± 0.39
Striatum8.73 ± 0.42
Subthalamus8.38 ± 0.2
Temporal Lobe8.28 ± 0.29
Thalamus8.76 ± 0.25
White Matter9.54 ± 0.09
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
RhobCBCerebellum69.63
84.6
RhobCTXCerebral cortex100
100
RhobHIPHippocampal region100
100
RhobHPFHippocampal formation100
100
RhobHYHypothalamus100
100
RhobLSXLateral septal complex100
100
RhobMBMidbrain100
100
RhobMYMedulla100
100
RhobOLFOlfactory bulb100
100
RhobPPons100
100
RhobPALPallidum100
100
RhobRHPRetrohippocampal region100
100
RhobsAMYStriatum-like amygdalar nuclei100
100
RhobSTRStriatum100
100
RhobSTRdStriatum dorsal region100
100
RhobSTRvStriatum ventral region100
100
RhobTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003292 15 105 119 HFCPNVPIILVANKK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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