AutismKB 2.0

Annotation Detail for TMEM220


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Basic Information Top
Gene Symbol:TMEM220 ( - )
Gene Full Name: transmembrane protein 220
Band: 17p13.1
Quick LinksEntrez ID:388335; OMIM: NA; Uniprot ID:TM220_HUMAN; ENSEMBL ID: ENSG00000187824; HGNC ID: 33757
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus12 / 56401221
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult19 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal38 / 336030711
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain8 / 11009897
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus1 / 2020949
eye1 / 2110544
heart0 / 896260 
intestine1 / 2344724
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate7 / 18934536
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach2 / 9661920
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P116700
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.16 ± 0.91
Basal Forebrain2.95 ± 0.32
Basal Part of Pons2.42 ± 0.41
Cerebellar Cortex2.43 ± 0.58
Cerebellar Nuclei2.93 ± 0.73
Claustrum3.35 ± 0.79
Epithalamus3.83 ± 0.41
Frontal Lobe2.79 ± 0.74
Globus Pallidus4.14 ± 0.44
Hypothalamus3.23 ± 0.58
Insula2.82 ± 0.57
Limbic Lobe2.75 ± 0.72
Mesencephalon3.07 ± 0.64
Myelencephalon2.95 ± 0.75
Occipital Lobe2.93 ± 0.73
Parietal Lobe2.76 ± 0.71
Pontine Tegmentum2.86 ± 0.78
Striatum3.54 ± 0.66
Subthalamus2.83 ± 0.66
Temporal Lobe2.66 ± 0.71
Thalamus2.91 ± 0.6
White Matter2.65 ± 0.54
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
A730055C05RikCBCerebellum1.23
1.7
A730055C05RikCTXCerebral cortex2.25
1.8
A730055C05RikHIPHippocampal region2.09
1.89
A730055C05RikHPFHippocampal formation1.68
1.42
A730055C05RikHYHypothalamus0.23
0.25
A730055C05RikLSXLateral septal complex0.3
0.31
A730055C05RikMBMidbrain0.47
0.67
A730055C05RikMYMedulla0.97
1.1
A730055C05RikOLFOlfactory bulb2.68
2.77
A730055C05RikPPons0.28
0.32
A730055C05RikPALPallidum0.18
0.15
A730055C05RikRHPRetrohippocampal region0.98
0.78
A730055C05RiksAMYStriatum-like amygdalar nuclei0.11
0.35
A730055C05RikSTRStriatum0.53
0.62
A730055C05RikSTRdStriatum dorsal region0.69
0.61
A730055C05RikSTRvStriatum ventral region0.16
0.96
A730055C05RikTHThalamus8.34
10.82
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018