AutismKB 2.0

Annotation Detail for KRT81


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Basic Information Top
Gene Symbol:KRT81 ( HB1,Hb-1,KRTHB1,MLN137,ghHkb1,hHAKB2-1 )
Gene Full Name: keratin 81
Band: 12q13.13
Quick LinksEntrez ID:3887; OMIM: 602153; Uniprot ID:KRT81_HUMAN; ENSEMBL ID: ENSG00000205426; HGNC ID: 6458
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult155 / 193912179
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor75 / 94178796
cervical tumor0 / 343660 
chondrosarcoma38 / 82823458
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor35 / 103127339
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal13 / 33603073
ovarian tumor0 / 766820 
pancreatic tumor23 / 104616219
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor34 / 125191271
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone41 / 71655572
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue34 / 149255227
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart2 / 8962622
intestine1 / 2344724
kidney0 / 2117770 
larynx1 / 2414541
liver0 / 2077430 
lung35 / 336974103
lymph0 / 442700 
lymph node0 / 916100 
mammary gland75 / 153271489
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas23 / 214812107
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta3 / 28082510
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213711_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.1
Adipocyte20.55
AdrenalCortex20.95
Adrenalgland11.8
Amygdala13.55
Appendix13.2
AtrioventricularNode10.05
BDCA4+_DentriticCells12.45
Bonemarrow14.5
BronchialEpithelialCells12.75
CD105+_Endothelial12.9
CD14+_Monocytes13.2
CD19+_BCells(neg._sel.)13.65
CD33+_Myeloid13.8
CD34+15.45
CD4+_Tcells12.95
CD56+_NKCells12.5
CD71+_EarlyErythroid12.25
CD8+_Tcells10.05
CardiacMyocytes17.55
Caudatenucleus12.15
Cerebellum11
CerebellumPeduncles15.2
CiliaryGanglion10.45
CingulateCortex15.5
Colorectaladenocarcinoma29.3
DorsalRootGanglion10.1
FetalThyroid13.05
Fetalbrain13.3
Fetalliver11.6
Fetallung9.7
GlobusPallidus10.8
Heart23.9
Hypothalamus13.75
Kidney18.8
Leukemia_chronicMyelogenousK-56212.05
Leukemia_promyelocytic-HL-6011.75
Leukemialymphoblastic(MOLT-4)10.65
Liver19.4
Lung13.1
Lymphnode11.6
Lymphoma_burkitts(Daudi)17.1
Lymphoma_burkitts(Raji)18.65
MedullaOblongata12.4
OccipitalLobe12
OlfactoryBulb10.5
Ovary8.8
Pancreas9.5
PancreaticIslet14.1
ParietalLobe15.25
Pituitary15.6
Placenta15.3
Pons13.35
PrefrontalCortex14.1
Prostate15.25
Salivarygland13.9
SkeletalMuscle20.85
Skin11.35
SmoothMuscle15.15
Spinalcord17.35
SubthalamicNucleus14.55
SuperiorCervicalGanglion16.2
TemporalLobe12.2
Testis11.45
TestisGermCell10.95
TestisIntersitial10.45
TestisLeydigCell13
TestisSeminiferousTubule11.45
Thalamus20.8
Thymus10.6
Thyroid16.05
Tongue16
Tonsil12.9
Trachea15
TrigeminalGanglion11.85
Uterus10.5
UterusCorpus13.15
WholeBlood14.25
Wholebrain11.45
colon13.15
pineal_day16.34
pineal_night15.7
retina15.85
small_intestine12.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7494_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.88 ± 1.02
Basal Forebrain1.67 ± 0.36
Basal Part of Pons1.16 ± 0.4
Cerebellar Cortex1.26 ± 0.69
Cerebellar Nuclei1.78 ± 0.64
Claustrum2.18 ± 0.85
Epithalamus1.22 ± 0.77
Frontal Lobe1.48 ± 0.75
Globus Pallidus1.92 ± 0.46
Hypothalamus1.54 ± 0.7
Insula1.19 ± 0.49
Limbic Lobe1.39 ± 0.6
Mesencephalon1.59 ± 0.71
Myelencephalon1.51 ± 0.67
Occipital Lobe1.33 ± 0.57
Parietal Lobe1.43 ± 0.71
Pontine Tegmentum1.5 ± 0.66
Striatum1.63 ± 0.64
Subthalamus1.59 ± 0.61
Temporal Lobe1.37 ± 0.67
Thalamus1.42 ± 0.68
White Matter1.75 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Krt81CBCerebellum5.65
7.15
Krt81CTXCerebral cortex1.65
2.36
Krt81HIPHippocampal region0.62
1.02
Krt81HPFHippocampal formation0.75
1.2
Krt81HYHypothalamus0.64
0.62
Krt81LSXLateral septal complex0.44
0.36
Krt81MBMidbrain2.46
3.4
Krt81MYMedulla3.88
5.89
Krt81OLFOlfactory bulb0.77
0.83
Krt81PPons0.93
1.07
Krt81PALPallidum0.32
0.25
Krt81RHPRetrohippocampal region0.88
1.36
Krt81sAMYStriatum-like amygdalar nuclei0
0
Krt81STRStriatum0.43
0.49
Krt81STRdStriatum dorsal region0.52
0.63
Krt81STRvStriatum ventral region0.33
0.34
Krt81THThalamus0.51
0.74
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
KRT81_HUMAN_271 18 271 288 MDCIIAEIKAQYDDIVTR PRIDE
KRT81_HUMAN_341 25 341 365 CQNSKLEAAVAQSEQQGEAALSDAR PRIDE
PAp00044631 10 368 377 LAELEGALQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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