AutismKB 2.0

Annotation Detail for CAPN8


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Basic Information Top
Gene Symbol:CAPN8 ( nCL-2 )
Gene Full Name: calpain 8
Band: 1q41
Quick LinksEntrez ID:388743; OMIM: NA; Uniprot ID:CAN8_HUMAN; ENSEMBL ID: ENSG00000203697; ENSG00000184445; HGNC ID: 1485
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult32 / 193912116
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor16 / 119369134
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal18 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites6 / 40015149
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart2 / 8962622
intestine7 / 23447229
kidney1 / 2117774
larynx1 / 2414541
liver0 / 2077430 
lung4 / 33697411
lymph0 / 442700 
lymph node1 / 9161010
mammary gland4 / 15327126
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach16 / 96619165
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P83381
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.37 ± 0.89
Basal Forebrain2.92 ± 0.88
Basal Part of Pons2.86 ± 0.64
Cerebellar Cortex2.83 ± 0.85
Cerebellar Nuclei2.97 ± 0.76
Claustrum3.39 ± 0.76
Epithalamus3.57 ± 0.77
Frontal Lobe2.82 ± 0.73
Globus Pallidus3.07 ± 0.83
Hypothalamus2.92 ± 0.67
Insula2.88 ± 0.99
Limbic Lobe3.02 ± 0.69
Mesencephalon3.1 ± 0.76
Myelencephalon2.96 ± 0.74
Occipital Lobe3.2 ± 0.66
Parietal Lobe2.92 ± 0.68
Pontine Tegmentum2.94 ± 0.71
Striatum3.22 ± 0.7
Subthalamus2.98 ± 0.69
Temporal Lobe2.81 ± 0.79
Thalamus2.77 ± 0.7
White Matter2.53 ± 0.26
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018