AutismKB 2.0

Annotation Detail for KRT85


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Basic Information Top
Gene Symbol:KRT85 ( HB5,Hb-5,KRTHB5,hHb5 )
Gene Full Name: keratin 85
Band: 12q13.13
Quick LinksEntrez ID:3891; OMIM: 602767; Uniprot ID:KRT85_HUMAN; ENSEMBL ID: ENSG00000135443; HGNC ID: 6462
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult2 / 19391211
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207670_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.1
Adipocyte4.25
AdrenalCortex4.85
Adrenalgland3.7
Amygdala4.4
Appendix4.65
AtrioventricularNode3.45
BDCA4+_DentriticCells4.5
Bonemarrow4.4
BronchialEpithelialCells4.2
CD105+_Endothelial4.25
CD14+_Monocytes4.55
CD19+_BCells(neg._sel.)4.45
CD33+_Myeloid5.4
CD34+5.25
CD4+_Tcells4.45
CD56+_NKCells5
CD71+_EarlyErythroid4.05
CD8+_Tcells4.05
CardiacMyocytes6
Caudatenucleus3.85
Cerebellum3.5
CerebellumPeduncles5
CiliaryGanglion3.5
CingulateCortex4.85
Colorectaladenocarcinoma4.3
DorsalRootGanglion3.7
FetalThyroid4.35
Fetalbrain4.2
Fetalliver3.8
Fetallung3.45
GlobusPallidus3.25
Heart5.85
Hypothalamus4.6
Kidney3.7
Leukemia_chronicMyelogenousK-5623.9
Leukemia_promyelocytic-HL-603.75
Leukemialymphoblastic(MOLT-4)3.55
Liver5.95
Lung4.7
Lymphnode3.65
Lymphoma_burkitts(Daudi)5.55
Lymphoma_burkitts(Raji)6.2
MedullaOblongata3.9
OccipitalLobe3.85
OlfactoryBulb3.35
Ovary3.15
Pancreas3.7
PancreaticIslet4.65
ParietalLobe4.7
Pituitary5
Placenta4.3
Pons4.7
PrefrontalCortex5.25
Prostate4.95
Salivarygland3.55
SkeletalMuscle5.4
Skin3.55
SmoothMuscle4.85
Spinalcord4.6
SubthalamicNucleus4
SuperiorCervicalGanglion5.3
TemporalLobe4
Testis3.7
TestisGermCell3.5
TestisIntersitial3.65
TestisLeydigCell4.7
TestisSeminiferousTubule3.75
Thalamus5
Thymus3.35
Thyroid5.3
Tongue4.4
Tonsil4.25
Trachea3.6
TrigeminalGanglion5.15
Uterus3.45
UterusCorpus3.95
WholeBlood4.6
Wholebrain3.5
colon4.35
pineal_day5.28
pineal_night5.2
retina5.2
small_intestine4.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7509_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.2 ± 0.76
Basal Forebrain2.68 ± 0.87
Basal Part of Pons2.62 ± 0.93
Cerebellar Cortex2.49 ± 0.86
Cerebellar Nuclei2.76 ± 0.48
Claustrum3.5 ± 0.77
Epithalamus2.37 ± 0.68
Frontal Lobe2.8 ± 0.93
Globus Pallidus3.73 ± 0.73
Hypothalamus2.53 ± 0.48
Insula2.43 ± 0.65
Limbic Lobe3.04 ± 0.99
Mesencephalon2.98 ± 0.91
Myelencephalon2.96 ± 0.93
Occipital Lobe2.73 ± 1.01
Parietal Lobe2.99 ± 0.94
Pontine Tegmentum2.74 ± 0.7
Striatum3.07 ± 0.91
Subthalamus3.44 ± 0.47
Temporal Lobe2.8 ± 0.87
Thalamus2.79 ± 0.91
White Matter2.83 ± 0.5
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
KRT85_HUMAN_133 9 133 141 FAAFIDKVR PRIDE
KRT85_HUMAN_134 7 134 140 FAAFIDK PRIDE
KRT85_HUMAN_192 17 192 208 LASELNHVQEVLEGYKK PRIDE
KRT85_HUMAN_210 9 210 218 KYEEEVALR PRIDE
KRT85_HUMAN_219 11 219 229 ATAENEFVVLK PRIDE
KRT85_HUMAN_219 12 219 230 ATAENEFVVLKK PRIDE
KRT85_HUMAN_265 14 265 278 VLQAHISDTSVIVK PRIDE
KRT85_HUMAN_266 14 266 279 VLQAHISDTSVIVK PRIDE
KRT85_HUMAN_306 10 306 315 SRAEAESWYR PRIDE
KRT85_HUMAN_335 10 335 344 TKEEINELNR PRIDE
KRT85_HUMAN_394 10 394 403 AKQDMACLLK PRIDE
KRT85_HUMAN_395 10 395 404 AKQDMACLLK PRIDE
KRT85_HUMAN_413 11 413 423 LGLDIEIATYR PRIDE
PAp00044631 10 385 394 LAELEGALQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018