AutismKB 2.0

Annotation Detail for VGLL3


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Basic Information Top
Gene Symbol:VGLL3 ( DKFZp686O1845,FLJ38507,VGL-3,VGL3 )
Gene Full Name: vestigial like 3 (Drosophila)
Band: 3p12.1
Quick LinksEntrez ID:389136; OMIM: 609980; Uniprot ID:VGLL3_HUMAN; ENSEMBL ID: ENSG00000206538; HGNC ID: 24327
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst3 / 6231948
fetus8 / 56401214
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult133 / 193912168
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal196 / 336030758
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow4 / 4880181
brain9 / 11009898
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine2 / 2344728
kidney0 / 2117770 
larynx0 / 241450 
liver2 / 2077439
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle3 / 10771527
nerve2 / 15768126
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta133 / 280825473
prostate2 / 18934510
salivary gland0 / 201550 
skin6 / 21057428
spleen0 / 539520 
stomach0 / 966190 
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220327_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.6
Adipocyte10.5
AdrenalCortex12.15
Adrenalgland8.35
Amygdala9.2
Appendix15.3
AtrioventricularNode12.55
BDCA4+_DentriticCells8.2
Bonemarrow10.85
BronchialEpithelialCells8.45
CD105+_Endothelial8.8
CD14+_Monocytes9.75
CD19+_BCells(neg._sel.)9.25
CD33+_Myeloid10.5
CD34+10.65
CD4+_Tcells8.9
CD56+_NKCells9.6
CD71+_EarlyErythroid8.7
CD8+_Tcells7.55
CardiacMyocytes19.2
Caudatenucleus7.95
Cerebellum7.25
CerebellumPeduncles11.05
CiliaryGanglion11.2
CingulateCortex9.65
Colorectaladenocarcinoma8.85
DorsalRootGanglion10.05
FetalThyroid9.85
Fetalbrain8.15
Fetalliver7.95
Fetallung7
GlobusPallidus7.85
Heart19.9
Hypothalamus8.75
Kidney9
Leukemia_chronicMyelogenousK-5627.9
Leukemia_promyelocytic-HL-607.8
Leukemialymphoblastic(MOLT-4)6.75
Liver16.05
Lung9.75
Lymphnode7.3
Lymphoma_burkitts(Daudi)12.15
Lymphoma_burkitts(Raji)15.3
MedullaOblongata8
OccipitalLobe7.8
OlfactoryBulb8.5
Ovary7.55
Pancreas8.25
PancreaticIslet10.5
ParietalLobe9.95
Pituitary10.5
Placenta65.95
Pons9.5
PrefrontalCortex9.85
Prostate10.2
Salivarygland7.55
SkeletalMuscle19.45
Skin9.1
SmoothMuscle10
Spinalcord9.55
SubthalamicNucleus9
SuperiorCervicalGanglion18.85
TemporalLobe8.75
Testis7.6
TestisGermCell7
TestisIntersitial8.4
TestisLeydigCell9.75
TestisSeminiferousTubule7.6
Thalamus9.4
Thymus6.5
Thyroid10.95
Tongue10.7
Tonsil8.9
Trachea7.45
TrigeminalGanglion18.8
Uterus13.95
UterusCorpus10.4
WholeBlood9.3
Wholebrain7.2
colon11.6
pineal_day10.52
pineal_night10.52
retina11.325
small_intestine8.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P67585
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.74 ± 0.7
Basal Forebrain4.75 ± 0.56
Basal Part of Pons4.4 ± 0.3
Cerebellar Cortex4.37 ± 0.41
Cerebellar Nuclei4.54 ± 0.4
Claustrum4.6 ± 0.76
Epithalamus4.24 ± 0.61
Frontal Lobe4.45 ± 0.5
Globus Pallidus5.22 ± 0.43
Hypothalamus4.41 ± 0.51
Insula4.5 ± 0.44
Limbic Lobe4.49 ± 0.41
Mesencephalon4.5 ± 0.52
Myelencephalon4.5 ± 0.53
Occipital Lobe4.28 ± 0.47
Parietal Lobe4.43 ± 0.47
Pontine Tegmentum4.45 ± 0.44
Striatum4.69 ± 0.4
Subthalamus4.88 ± 0.33
Temporal Lobe4.42 ± 0.48
Thalamus4.46 ± 0.42
White Matter4.97 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
1700110N18RikCBCerebellum100
100
1700110N18RikCTXCerebral cortex100
100
1700110N18RikHIPHippocampal region76.74
100
1700110N18RikHPFHippocampal formation67.93
93.26
1700110N18RikHYHypothalamus11.51
11.29
1700110N18RikLSXLateral septal complex49.45
44.08
1700110N18RikMBMidbrain37.76
44.08
1700110N18RikMYMedulla49.66
64.58
1700110N18RikOLFOlfactory bulb74.41
89.8
1700110N18RikPPons28.41
35.07
1700110N18RikPALPallidum33.24
39.56
1700110N18RikRHPRetrohippocampal region49.59
47.87
1700110N18RiksAMYStriatum-like amygdalar nuclei58.27
59.2
1700110N18RikSTRStriatum57.39
54.99
1700110N18RikSTRdStriatum dorsal region57.4
54.6
1700110N18RikSTRvStriatum ventral region59.96
57.26
1700110N18RikTHThalamus55.77
62.7
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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