Annotation Detail for IYD
Basic Information Top
| Gene Symbol: | IYD ( C6orf71,DEHAL1,TDH4,dJ422F24.1 ) |
|---|---|
| Gene Full Name: | iodotyrosine deiodinase |
| Band: | 6q25.1 |
| Quick Links | Entrez ID:389434; OMIM: 612025; Uniprot ID:IYD1_HUMAN; ENSEMBL ID: ENSG00000009765; HGNC ID: 21071 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.310225
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 10 / 564012 | 17 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 24 / 1939121 | 12 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 5 / 114246 | 43 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 |  |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 5 / 136302 | 36 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 39 / 3360307 | 11 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 0 / 1100989 | 0 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 7 / 234472 | 29 | |
| kidney | 19 / 211777 | 89 |  |
| larynx | 0 / 24145 | 0 | |
| liver | 1 / 207743 | 4 | |
| lung | 1 / 336974 | 2 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 3 / 153271 | 19 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 0 / 330442 | 0 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 10 / 47473 | 210 |  |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: A_23_P74114
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 11.74 ± 0.98 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 11.51 ± 0.28 | |
| Basal Part of Pons | 11.18 ± 0.36 | |
| Cerebellar Cortex | 11.22 ± 0.38 | |
| Cerebellar Nuclei | 11.95 ± 0.74 | |
| Claustrum | 12.27 ± 0.92 | |
| Epithalamus | 11.21 ± 0.44 | |
| Frontal Lobe | 11.3 ± 0.65 | |
| Globus Pallidus | 11.96 ± 0.35 | |
| Hypothalamus | 11.47 ± 0.7 | |
| Insula | 11.2 ± 0.47 | |
| Limbic Lobe | 11.4 ± 0.63 | |
| Mesencephalon | 11.7 ± 0.62 | |
| Myelencephalon | 11.48 ± 0.59 | |
| Occipital Lobe | 11.52 ± 0.55 | |
| Parietal Lobe | 11.5 ± 0.6 | |
| Pontine Tegmentum | 11.49 ± 0.64 | |
| Striatum | 11.73 ± 0.49 | |
| Subthalamus | 11.7 ± 0.43 | |
| Temporal Lobe | 11.29 ± 0.55 | |
| Thalamus | 11.56 ± 0.52 | |
| White Matter | 12.08 ± 0.44 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Iyd | CB | Cerebellum | 6.6 | |
| 8.25 | | |||
| Iyd | CTX | Cerebral cortex | 5.1 | |
| 2.99 | | |||
| Iyd | HIP | Hippocampal region | 10.47 | |
| 14.14 | | |||
| Iyd | HPF | Hippocampal formation | 8.24 | |
| 8.71 | | |||
| Iyd | HY | Hypothalamus | 1.09 | |
| 0.76 | | |||
| Iyd | LSX | Lateral septal complex | 0.42 | |
| 0.4 | | |||
| Iyd | MB | Midbrain | 1.72 | |
| 1.77 | | |||
| Iyd | MY | Medulla | 14.03 | |
| 20.27 | | |||
| Iyd | OLF | Olfactory bulb | 6.57 | |
| 4.18 | | |||
| Iyd | P | Pons | 3.12 | |
| 3.12 | | |||
| Iyd | PAL | Pallidum | 2.37 | |
| 1.2 | | |||
| Iyd | RHP | Retrohippocampal region | 5.15 | |
| 2.45 | | |||
| Iyd | sAMY | Striatum-like amygdalar nuclei | 8.88 | |
| 4.52 | | |||
| Iyd | STR | Striatum | 2.48 | |
| 1.23 | | |||
| Iyd | STRd | Striatum dorsal region | 1.74 | |
| 0.83 | | |||
| Iyd | STRv | Striatum ventral region | 2.49 | |
| 1.22 | | |||
| Iyd | TH | Thalamus | 14.42 | |
| 11.31 | |