Annotation Detail for L1CAM
Basic Information Top
| Gene Symbol: | L1CAM ( CAML1,CD171,HSAS,HSAS1,MASA,MIC5,N-CAML1,S10,SPG1 ) |
|---|---|
| Gene Full Name: | L1 cell adhesion molecule |
| Band: | Xq28 |
| Quick Links | Entrez ID:3897; OMIM: 308840; Uniprot ID:L1CAM_HUMAN; ENSEMBL ID: ENSG00000198910; HGNC ID: 6470 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.522818
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 3 / 62319 | 48 | |
| fetus | 50 / 564012 | 88 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 2 / 23620 | 84 | |
| juvenile | 5 / 55556 | 89 | |
| adult | 43 / 1939121 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 3 / 34366 | 87 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 9 / 263845 | 34 | |
| glioma | 19 / 106883 | 177 | |
| head and neck tumor | 1 / 136302 | 7 |  |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 5 / 96359 | 51 | |
| lung tumor | 5 / 103127 | 48 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 176 / 3360307 | 52 | |
| ovarian tumor | 7 / 76682 | 91 | |
| pancreatic tumor | 13 / 104616 | 124 | |
| primitive neuroectodermal tumor of the CNS | 27 / 125680 | 214 |  |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 9 / 124949 | 72 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 4 / 90257 | 44 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 184 / 1100989 | 167 | |
| cervix | 9 / 48171 | 186 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 5 / 215722 | 23 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 4 / 211054 | 18 | |
| heart | 0 / 89626 | 0 | |
| intestine | 6 / 234472 | 25 | |
| kidney | 4 / 211777 | 18 | |
| larynx | 1 / 24145 | 41 | |
| liver | 5 / 207743 | 24 | |
| lung | 6 / 336974 | 17 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 3 / 153271 | 19 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 5 / 15768 | 317 | |
| ovary | 7 / 102051 | 68 | |
| pancreas | 13 / 214812 | 60 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 2 / 280825 | 7 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 13 / 210574 | 61 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 7 / 330442 | 21 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 204585_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 4.75 | |
| Adipocyte | 3.75 | |
| AdrenalCortex | 3.8 | |
| Adrenalgland | 4.75 | |
| Amygdala | 4.1 | |
| Appendix | 3.6 | |
| AtrioventricularNode | 2.75 | |
| BDCA4+_DentriticCells | 4.05 | |
| Bonemarrow | 3.65 | |
| BronchialEpithelialCells | 3.75 | |
| CD105+_Endothelial | 3.65 | |
| CD14+_Monocytes | 4 | |
| CD19+_BCells(neg._sel.) | 4.05 | |
| CD33+_Myeloid | 4.55 | |
| CD34+ | 4.6 | |
| CD4+_Tcells | 4.2 | |
| CD56+_NKCells | 4.45 | |
| CD71+_EarlyErythroid | 3.5 | |
| CD8+_Tcells | 3.65 | |
| CardiacMyocytes | 4.7 | |
| Caudatenucleus | 4.75 | |
| Cerebellum | 4.65 | |
| CerebellumPeduncles | 4.3 | |
| CiliaryGanglion | 2.55 | |
| CingulateCortex | 3.9 | |
| Colorectaladenocarcinoma | 3.8 | |
| DorsalRootGanglion | 2.75 | |
| FetalThyroid | 3.65 | |
| Fetalbrain | 3.8 | |
| Fetalliver | 3.3 | |
| Fetallung | 3.25 | |
| GlobusPallidus | 3.75 | |
| Heart | 4.8 | |
| Hypothalamus | 4.2 | |
| Kidney | 4.8 | |
| Leukemia_chronicMyelogenousK-562 | 3.45 | |
| Leukemia_promyelocytic-HL-60 | 3.3 | |
| Leukemialymphoblastic(MOLT-4) | 3.1 | |
| Liver | 4.95 | |
| Lung | 4.25 | |
| Lymphnode | 3.3 | |
| Lymphoma_burkitts(Daudi) | 4.8 | |
| Lymphoma_burkitts(Raji) | 5.15 | |
| MedullaOblongata | 3.5 | |
| OccipitalLobe | 4.2 | |
| OlfactoryBulb | 3 | |
| Ovary | 2.8 | |
| Pancreas | 3 | |
| PancreaticIslet | 4 | |
| ParietalLobe | 3.95 | |
| Pituitary | 4.45 | |
| Placenta | 3.95 | |
| Pons | 3.6 | |
| PrefrontalCortex | 5.1 | |
| Prostate | 4.4 | |
| Salivarygland | 3 | |
| SkeletalMuscle | 4.15 | |
| Skin | 2.75 | |
| SmoothMuscle | 4.1 | |
| Spinalcord | 4.2 | |
| SubthalamicNucleus | 3.35 | |
| SuperiorCervicalGanglion | 4.1 | |
| TemporalLobe | 3.4 | |
| Testis | 3.3 | |
| TestisGermCell | 3.1 | |
| TestisIntersitial | 3.1 | |
| TestisLeydigCell | 3.7 | |
| TestisSeminiferousTubule | 3.25 | |
| Thalamus | 6.2 | |
| Thymus | 3.05 | |
| Thyroid | 4.85 | |
| Tongue | 3.65 | |
| Tonsil | 3.7 | |
| Trachea | 3.2 | |
| TrigeminalGanglion | 3.65 | |
| Uterus | 3.15 | |
| UterusCorpus | 3.3 | |
| WholeBlood | 4.2 | |
| Wholebrain | 3.35 | |
| colon | 3.8 | |
| pineal_day | 4.6 | |
| pineal_night | 4.6 | |
| retina | 4.625 | |
| small_intestine | 3.65 | |
- Probe name: A_23_P171324
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 7.08 ± 0.54 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.37 ± 0.35 | |
| Basal Part of Pons | 7 ± 0.38 | |
| Cerebellar Cortex | 6.34 ± 0.47 | |
| Cerebellar Nuclei | 5.7 ± 0.54 | |
| Claustrum | 7.44 ± 0.69 | |
| Epithalamus | 5.15 ± 0.79 | |
| Frontal Lobe | 6.22 ± 0.63 | |
| Globus Pallidus | 5.57 ± 0.41 | |
| Hypothalamus | 6.53 ± 0.49 | |
| Insula | 6.33 ± 0.55 | |
| Limbic Lobe | 6.86 ± 0.66 | |
| Mesencephalon | 6.42 ± 0.73 | |
| Myelencephalon | 6.46 ± 0.7 | |
| Occipital Lobe | 6.79 ± 0.68 | |
| Parietal Lobe | 6.51 ± 0.72 | |
| Pontine Tegmentum | 6.13 ± 0.77 | |
| Striatum | 6.6 ± 0.61 | |
| Subthalamus | 5.88 ± 0.3 | |
| Temporal Lobe | 6.41 ± 0.61 | |
| Thalamus | 6.38 ± 0.48 | |
| White Matter | 3.82 ± 0.24 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| L1cam | CB | Cerebellum | 7.93 | |
| 7.59 | | |||
| L1cam | CTX | Cerebral cortex | 16.99 | |
| 12.61 | | |||
| L1cam | HIP | Hippocampal region | 36.3 | |
| 30.08 | | |||
| L1cam | HPF | Hippocampal formation | 37.68 | |
| 31.64 | | |||
| L1cam | HY | Hypothalamus | 30.01 | |
| 20.78 | | |||
| L1cam | LSX | Lateral septal complex | 7.29 | |
| 4.61 | | |||
| L1cam | MB | Midbrain | 18.38 | |
| 16.09 | | |||
| L1cam | MY | Medulla | 18.62 | |
| 20.18 | | |||
| L1cam | OLF | Olfactory bulb | 37.77 | |
| 28.89 | | |||
| L1cam | P | Pons | 27.84 | |
| 26.19 | | |||
| L1cam | PAL | Pallidum | 15.63 | |
| 14.42 | | |||
| L1cam | RHP | Retrohippocampal region | 38.3 | |
| 31.69 | | |||
| L1cam | sAMY | Striatum-like amygdalar nuclei | 24.46 | |
| 15.84 | | |||
| L1cam | STR | Striatum | 7.93 | |
| 5.61 | | |||
| L1cam | STRd | Striatum dorsal region | 4.11 | |
| 3.39 | | |||
| L1cam | STRv | Striatum ventral region | 12.9 | |
| 7.78 | | |||
| L1cam | TH | Thalamus | 65.32 | |
| 59.09 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00009431 | 12 | 52 | 63 | CEASGKPEVQFR | Peptide Atlas |