AutismKB 2.0

Annotation Detail for IER5L


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Basic Information Top
Gene Symbol:IER5L ( MGC70833,bA247A12.2 )
Gene Full Name: immediate early response 5-like
Band: 9q34.11
Quick LinksEntrez ID:389792; OMIM: NA; Uniprot ID:IER5L_HUMAN; ENSEMBL ID: ENSG00000188483; HGNC ID: 23679
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult63 / 193912132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor40 / 119369335
germ cell tumor3 / 26384511
glioma5 / 10688346
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal51 / 336030715
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites6 / 40015149
bladder1 / 2975733
blood0 / 1234780 
bone7 / 7165597
bone marrow0 / 488010 
brain9 / 11009898
cervix4 / 4817183
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine3 / 23447212
kidney7 / 21177733
larynx0 / 241450 
liver2 / 2077439
lung7 / 33697420
lymph0 / 442700 
lymph node12 / 91610130
mammary gland4 / 15327126
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary4 / 10205139
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate4 / 18934521
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach26 / 96619269
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5171_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.38 ± 0.47
Basal Forebrain5.88 ± 0.52
Basal Part of Pons6.67 ± 0.46
Cerebellar Cortex5.97 ± 0.33
Cerebellar Nuclei6.3 ± 0.68
Claustrum6.46 ± 0.6
Epithalamus6.16 ± 0.19
Frontal Lobe6.55 ± 0.5
Globus Pallidus5.05 ± 0.65
Hypothalamus5.71 ± 0.67
Insula6.64 ± 0.29
Limbic Lobe6.19 ± 0.7
Mesencephalon6.06 ± 0.59
Myelencephalon6.14 ± 0.63
Occipital Lobe6.26 ± 0.56
Parietal Lobe6.56 ± 0.67
Pontine Tegmentum6.27 ± 0.51
Striatum6.05 ± 0.7
Subthalamus6.43 ± 0.22
Temporal Lobe6.43 ± 0.47
Thalamus6.12 ± 0.44
White Matter4.21 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ier5lCBCerebellum9.04
10.45
Ier5lCTXCerebral cortex57.85
45.21
Ier5lHIPHippocampal region14.71
15.78
Ier5lHPFHippocampal formation20.19
18.4
Ier5lHYHypothalamus2.53
2.25
Ier5lLSXLateral septal complex12.27
8.43
Ier5lMBMidbrain9.97
10.07
Ier5lMYMedulla14.1
15.55
Ier5lOLFOlfactory bulb31.65
25.28
Ier5lPPons10.82
11.45
Ier5lPALPallidum8.57
7.79
Ier5lRHPRetrohippocampal region29.59
22.38
Ier5lsAMYStriatum-like amygdalar nuclei9.74
6.49
Ier5lSTRStriatum17.5
13.4
Ier5lSTRdStriatum dorsal region16.67
12.74
Ier5lSTRvStriatum ventral region26.11
19.85
Ier5lTHThalamus11.22
9.75
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018