AutismKB 2.0

Annotation Detail for LAMA2


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Basic Information Top
Gene Symbol:LAMA2 ( LAMM )
Gene Full Name: laminin, alpha 2
Band: 6q22.33
Quick LinksEntrez ID:3908; OMIM: 156225; Uniprot ID:LAMA2_HUMAN; ENSEMBL ID: ENSG00000196569; HGNC ID: 6482
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus36 / 56401263
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult67 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor2 / 3436658
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor1 / 2638453
glioma5 / 10688346
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal126 / 336030737
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites2 / 4001549
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain26 / 110098923
cervix2 / 4817141
connective tissue0 / 1492550 
ear4 / 16212246
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye2 / 2110549
heart11 / 89626122
intestine3 / 23447212
kidney2 / 2117779
larynx2 / 2414582
liver7 / 20774333
lung10 / 33697429
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth1 / 6705214
muscle7 / 10771564
nerve1 / 1576863
ovary1 / 1020519
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta19 / 28082567
prostate1 / 1893455
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach2 / 9661920
testis10 / 33044230
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus16 / 23287868
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205116_at
Cell line Expression level Expression bar
721_B_lymphoblasts20.45
Adipocyte472.25
AdrenalCortex24.7
Adrenalgland21.25
Amygdala16.65
Appendix20.55
AtrioventricularNode35.95
BDCA4+_DentriticCells15.6
Bonemarrow20.15
BronchialEpithelialCells18.15
CD105+_Endothelial19.25
CD14+_Monocytes21.1
CD19+_BCells(neg._sel.)19.5
CD33+_Myeloid23.75
CD34+24.85
CD4+_Tcells19.85
CD56+_NKCells20.65
CD71+_EarlyErythroid18.75
CD8+_Tcells15.7
CardiacMyocytes29.25
Caudatenucleus18.05
Cerebellum16
CerebellumPeduncles26.3
CiliaryGanglion17.3
CingulateCortex20.9
Colorectaladenocarcinoma16.75
DorsalRootGanglion32.25
FetalThyroid22.6
Fetalbrain19.1
Fetalliver16.1
Fetallung71.35
GlobusPallidus16.05
Heart27.2
Hypothalamus21.1
Kidney17.1
Leukemia_chronicMyelogenousK-56217.15
Leukemia_promyelocytic-HL-6015.8
Leukemialymphoblastic(MOLT-4)14.55
Liver27
Lung20.55
Lymphnode15.55
Lymphoma_burkitts(Daudi)24.4
Lymphoma_burkitts(Raji)28.1
MedullaOblongata16.95
OccipitalLobe17.5
OlfactoryBulb54
Ovary54.9
Pancreas16.35
PancreaticIslet23.5
ParietalLobe32.55
Pituitary23.75
Placenta41.2
Pons22.5
PrefrontalCortex23.9
Prostate21.6
Salivarygland18.1
SkeletalMuscle41.95
Skin22.65
SmoothMuscle79.1
Spinalcord20.9
SubthalamicNucleus20.5
SuperiorCervicalGanglion27.85
TemporalLobe18.7
Testis16.4
TestisGermCell40.55
TestisIntersitial20.7
TestisLeydigCell19.9
TestisSeminiferousTubule27.95
Thalamus36.65
Thymus13.25
Thyroid23.5
Tongue21.25
Tonsil19.5
Trachea16.7
TrigeminalGanglion21.05
Uterus18.15
UterusCorpus19.35
WholeBlood20.7
Wholebrain14.7
colon20.05
pineal_day27.16
pineal_night24.92
retina23.925
small_intestine19.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P70719
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.89 ± 0.8
Basal Forebrain3.81 ± 0.32
Basal Part of Pons3.78 ± 0.56
Cerebellar Cortex4.09 ± 0.69
Cerebellar Nuclei4.35 ± 0.48
Claustrum3.63 ± 0.9
Epithalamus4.26 ± 0.73
Frontal Lobe4.47 ± 0.54
Globus Pallidus4.84 ± 0.41
Hypothalamus3.8 ± 0.7
Insula4.09 ± 0.44
Limbic Lobe3.84 ± 0.57
Mesencephalon4.18 ± 0.6
Myelencephalon4.22 ± 0.62
Occipital Lobe3.7 ± 0.61
Parietal Lobe4.06 ± 0.57
Pontine Tegmentum4 ± 0.69
Striatum4.32 ± 0.57
Subthalamus4.81 ± 0.38
Temporal Lobe3.76 ± 0.55
Thalamus4.2 ± 0.58
White Matter3.93 ± 0.83
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
LAMA2_HUMAN_2578 14 2578 2591 RQTGQAYYVILLNR PRIDE
PAp00156854 22 554 575 VAPQQDDLDSPQQISISNAEAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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