AutismKB 2.0

Annotation Detail for LAMA3


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Basic Information Top
Gene Symbol:LAMA3 ( BM600,E170,LAMNA,LOCS,lama3a )
Gene Full Name: laminin, alpha 3
Band: 18q11.2
Quick LinksEntrez ID:3909; OMIM: 600805; Uniprot ID:LAMA3_HUMAN; ENSEMBL ID: ENSG00000053747; HGNC ID: 6483
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult151 / 193912177
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor11 / 11424696
esophageal tumor9 / 17290520
gastrointestinal tumor4 / 11936933
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor68 / 136302498
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal60 / 336030717
ovarian tumor1 / 7668213
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer6 / 10268058
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor22 / 90257243
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder3 / 29757100
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain4 / 11009893
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus9 / 20209445
eye8 / 21105437
heart4 / 8962644
intestine12 / 23447251
kidney2 / 2117779
larynx5 / 24145207
liver5 / 20774324
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth63 / 67052939
muscle6 / 10771555
nerve0 / 157680 
ovary1 / 1020519
pancreas7 / 21481232
parathyroid1 / 2053948
pharynx4 / 4132896
pituitary gland0 / 165850 
placenta11 / 28082539
prostate9 / 18934547
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach4 / 9661941
testis7 / 33044221
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus27 / 232878115
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203726_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.8
Adipocyte4.2
AdrenalCortex4.1
Adrenalgland3.3
Amygdala4
Appendix3.85
AtrioventricularNode3
BDCA4+_DentriticCells4.2
Bonemarrow3.75
BronchialEpithelialCells1799.95
CD105+_Endothelial3.9
CD14+_Monocytes4.1
CD19+_BCells(neg._sel.)4.1
CD33+_Myeloid4.95
CD34+4.9
CD4+_Tcells4.15
CD56+_NKCells4.6
CD71+_EarlyErythroid3.55
CD8+_Tcells3.7
CardiacMyocytes4.8
Caudatenucleus3.45
Cerebellum3.1
CerebellumPeduncles4.35
CiliaryGanglion2.8
CingulateCortex3.95
Colorectaladenocarcinoma30.3
DorsalRootGanglion2.95
FetalThyroid3.7
Fetalbrain3.85
Fetalliver3.3
Fetallung31.3
GlobusPallidus2.8
Heart5
Hypothalamus4.15
Kidney3.15
Leukemia_chronicMyelogenousK-5623.45
Leukemia_promyelocytic-HL-603.4
Leukemialymphoblastic(MOLT-4)3.1
Liver5
Lung4.3
Lymphnode3.45
Lymphoma_burkitts(Daudi)4.9
Lymphoma_burkitts(Raji)5.3
MedullaOblongata3.55
OccipitalLobe3.45
OlfactoryBulb4.6
Ovary2.55
Pancreas22.5
PancreaticIslet4.15
ParietalLobe4.05
Pituitary4.45
Placenta11.2
Pons3.65
PrefrontalCortex4.75
Prostate4.6
Salivarygland3.1
SkeletalMuscle4.55
Skin3.65
SmoothMuscle4.35
Spinalcord4.1
SubthalamicNucleus3.45
SuperiorCervicalGanglion4.4
TemporalLobe3.45
Testis3.3
TestisGermCell3.75
TestisIntersitial3.2
TestisLeydigCell3.75
TestisSeminiferousTubule3.3
Thalamus3.9
Thymus3.95
Thyroid4.75
Tongue3.75
Tonsil3.7
Trachea5.55
TrigeminalGanglion3.95
Uterus8.35
UterusCorpus3.65
WholeBlood4.2
Wholebrain3.25
colon3.85
pineal_day4.84
pineal_night4.78
retina4.625
small_intestine3.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P687302
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.14 ± 0.87
Basal Forebrain2.5 ± 0.58
Basal Part of Pons2.12 ± 0.48
Cerebellar Cortex2.17 ± 0.51
Cerebellar Nuclei3.11 ± 0.74
Claustrum3.05 ± 0.71
Epithalamus2.89 ± 0.61
Frontal Lobe2.3 ± 0.69
Globus Pallidus3.53 ± 0.69
Hypothalamus2.42 ± 0.61
Insula2.26 ± 0.29
Limbic Lobe2.53 ± 0.76
Mesencephalon2.82 ± 0.79
Myelencephalon2.56 ± 0.64
Occipital Lobe2.91 ± 0.83
Parietal Lobe2.52 ± 0.64
Pontine Tegmentum2.69 ± 0.71
Striatum2.99 ± 0.69
Subthalamus2.69 ± 0.54
Temporal Lobe2.51 ± 0.76
Thalamus2.49 ± 0.66
White Matter3.22 ± 0.83
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
LAMA3_HUMAN_1048 11 1048 1058 RGVGDAINNGR PRIDE
PAp00095297 22 124 145 ACPCPHTNSFATGCVVNGGDVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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