AutismKB 2.0

Annotation Detail for LAMA5


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LAMA5 ( KIAA1907 )
Gene Full Name: laminin, alpha 5
Band: 20q13.33
Quick LinksEntrez ID:3911; OMIM: 601033; Uniprot ID:LAMA5_HUMAN; ENSEMBL ID: ENSG00000130702; HGNC ID: 6485
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body20 / 70761282
blastocyst21 / 62319336
fetus29 / 56401251
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult145 / 193912174
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma4 / 17475228
breast (mammary gland) tumor7 / 9417874
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor11 / 11424696
esophageal tumor7 / 17290404
gastrointestinal tumor16 / 119369134
germ cell tumor16 / 26384560
glioma15 / 106883140
head and neck tumor12 / 13630288
kidney tumor5 / 6895972
leukemia1 / 9584210
liver tumor8 / 9635983
lung tumor8 / 10312777
lymphoma1 / 7175513
non-neoplasia6 / 9725061
normal212 / 336030763
ovarian tumor17 / 76682221
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer12 / 102680116
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites12 / 40015299
bladder2 / 2975767
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain52 / 110098947
cervix4 / 4817183
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue49 / 215722227
esophagus7 / 20209346
eye14 / 21105466
heart5 / 8962655
intestine16 / 23447268
kidney7 / 21177733
larynx1 / 2414541
liver11 / 20774352
lung27 / 33697480
lymph0 / 442700 
lymph node2 / 9161021
mammary gland8 / 15327152
mouth7 / 67052104
muscle0 / 1077150 
nerve4 / 15768253
ovary25 / 102051244
pancreas29 / 214812135
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta25 / 28082589
prostate20 / 189345105
salivary gland0 / 201550 
skin4 / 21057418
spleen2 / 5395237
stomach5 / 9661951
testis13 / 33044239
thymus6 / 8113173
thyroid7 / 47473147
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus16 / 23287868
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210150_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.9
Adipocyte16.9
AdrenalCortex23.8
Adrenalgland17.45
Amygdala26
Appendix26.3
AtrioventricularNode15.6
BDCA4+_DentriticCells23.5
Bonemarrow20.35
BronchialEpithelialCells42.6
CD105+_Endothelial15.6
CD14+_Monocytes9.05
CD19+_BCells(neg._sel.)31.75
CD33+_Myeloid18.25
CD34+23.3
CD4+_Tcells9.55
CD56+_NKCells9.7
CD71+_EarlyErythroid19.05
CD8+_Tcells8.4
CardiacMyocytes25.75
Caudatenucleus18.75
Cerebellum21.25
CerebellumPeduncles33.15
CiliaryGanglion14.25
CingulateCortex21.05
Colorectaladenocarcinoma570.6
DorsalRootGanglion15.55
FetalThyroid38.35
Fetalbrain24.15
Fetalliver14.75
Fetallung52.4
GlobusPallidus14.95
Heart30.35
Hypothalamus23.4
Kidney17.7
Leukemia_chronicMyelogenousK-56219.05
Leukemia_promyelocytic-HL-6011.5
Leukemialymphoblastic(MOLT-4)13.65
Liver27
Lung64.7
Lymphnode20.2
Lymphoma_burkitts(Daudi)18.8
Lymphoma_burkitts(Raji)28.4
MedullaOblongata18.7
OccipitalLobe18.7
OlfactoryBulb27.1
Ovary13.45
Pancreas25.35
PancreaticIslet24.5
ParietalLobe21.7
Pituitary24.35
Placenta73.8
Pons19.8
PrefrontalCortex27.85
Prostate70
Salivarygland21.25
SkeletalMuscle19.4
Skin15.8
SmoothMuscle25.05
Spinalcord23.4
SubthalamicNucleus18.9
SuperiorCervicalGanglion23.05
TemporalLobe18.75
Testis19.3
TestisGermCell17.25
TestisIntersitial17.25
TestisLeydigCell19.65
TestisSeminiferousTubule18.05
Thalamus21.25
Thymus17.7
Thyroid93.95
Tongue22.25
Tonsil21.1
Trachea18.1
TrigeminalGanglion20.2
Uterus54.25
UterusCorpus18.45
WholeBlood12.15
Wholebrain17.8
colon23.25
pineal_day26.44
pineal_night31.38
retina31.825
small_intestine20.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9380_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.39 ± 1.09
Basal Forebrain1.85 ± 0.23
Basal Part of Pons1.58 ± 0.38
Cerebellar Cortex2.36 ± 0.74
Cerebellar Nuclei2.24 ± 0.84
Claustrum2.77 ± 0.88
Epithalamus1.66 ± 0.79
Frontal Lobe1.8 ± 0.77
Globus Pallidus2.09 ± 0.51
Hypothalamus1.87 ± 0.83
Insula1.91 ± 1.08
Limbic Lobe1.87 ± 0.85
Mesencephalon2.08 ± 0.8
Myelencephalon1.93 ± 0.74
Occipital Lobe2 ± 0.81
Parietal Lobe1.87 ± 0.82
Pontine Tegmentum1.95 ± 0.79
Striatum1.76 ± 0.92
Subthalamus2.01 ± 0.71
Temporal Lobe1.7 ± 0.61
Thalamus1.93 ± 0.67
White Matter2.23 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lama5CBCerebellum2.25
3.52
Lama5CTXCerebral cortex2.89
2.91
Lama5HIPHippocampal region3.92
4.55
Lama5HPFHippocampal formation3.65
3.87
Lama5HYHypothalamus0.82
0.6
Lama5LSXLateral septal complex0.56
0.45
Lama5MBMidbrain3.17
3.53
Lama5MYMedulla4.69
4.58
Lama5OLFOlfactory bulb3.55
3.15
Lama5PPons2.84
3.46
Lama5PALPallidum0.56
0.55
Lama5RHPRetrohippocampal region2.68
2.34
Lama5sAMYStriatum-like amygdalar nuclei2.6
2.99
Lama5STRStriatum2.09
1.77
Lama5STRdStriatum dorsal region2.63
2.16
Lama5STRvStriatum ventral region0.72
0.44
Lama5THThalamus8.32
6.64
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
LAMA5_HUMAN_1483 7 1483 1489 PCDCGAR PRIDE
PAp00009244 10 748 757 AHVEGPSCDR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved