Annotation Detail for LAMB2
Basic Information Top
| Gene Symbol: | LAMB2 ( LAMS ) |
|---|---|
| Gene Full Name: | laminin, beta 2 (laminin S) |
| Band: | 3p21.31 |
| Quick Links | Entrez ID:3913; OMIM: 150325; Uniprot ID:LAMB2_HUMAN; ENSEMBL ID: ENSG00000172037; HGNC ID: 6487 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.439726
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 14 / 70761 | 197 |  |
| blastocyst | 8 / 62319 | 128 | |
| fetus | 35 / 564012 | 62 | |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 |  |
| juvenile | 4 / 55556 | 71 | |
| adult | 239 / 1939121 | 123 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 12 / 94178 | 127 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 19 / 82823 | 229 |  |
| colorectal tumor | 10 / 114246 | 87 | |
| esophageal tumor | 2 / 17290 | 115 | |
| gastrointestinal tumor | 10 / 119369 | 83 | |
| germ cell tumor | 14 / 263845 | 53 | |
| glioma | 9 / 106883 | 84 | |
| head and neck tumor | 16 / 136302 | 117 | |
| kidney tumor | 4 / 68959 | 58 | |
| leukemia | 1 / 95842 | 10 |  |
| liver tumor | 10 / 96359 | 103 | |
| lung tumor | 10 / 103127 | 96 | |
| lymphoma | 3 / 71755 | 41 | |
| non-neoplasia | 8 / 97250 | 82 | |
| normal | 316 / 3360307 | 94 | |
| ovarian tumor | 4 / 76682 | 52 | |
| pancreatic tumor | 10 / 104616 | 95 | |
| primitive neuroectodermal tumor of the CNS | 5 / 125680 | 39 | |
| prostate cancer | 16 / 102680 | 155 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 16 / 124949 | 128 | |
| soft tissue/muscle tissue tumor | 7 / 125191 | 55 | |
| uterine tumor | 18 / 90257 | 199 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 6 / 13106 | 457 | |
| adrenal gland | 2 / 33197 | 60 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 1 / 123478 | 8 | |
| bone | 17 / 71655 | 237 | |
| bone marrow | 3 / 48801 | 61 | |
| brain | 64 / 1100989 | 58 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 16 / 149255 | 107 | |
| ear | 1 / 16212 | 61 | |
| embryonic tissue | 25 / 215722 | 115 | |
| esophagus | 2 / 20209 | 98 | |
| eye | 40 / 211054 | 189 | |
| heart | 14 / 89626 | 156 | |
| intestine | 23 / 234472 | 98 | |
| kidney | 13 / 211777 | 61 | |
| larynx | 2 / 24145 | 82 | |
| liver | 14 / 207743 | 67 | |
| lung | 55 / 336974 | 163 | |
| lymph | 3 / 44270 | 67 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 23 / 153271 | 150 | |
| mouth | 4 / 67052 | 59 | |
| muscle | 11 / 107715 | 102 | |
| nerve | 5 / 15768 | 317 | |
| ovary | 11 / 102051 | 107 | |
| pancreas | 10 / 214812 | 46 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 2 / 41328 | 48 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 25 / 280825 | 89 | |
| prostate | 26 / 189345 | 137 | |
| salivary gland | 2 / 20155 | 99 | |
| skin | 27 / 210574 | 128 | |
| spleen | 7 / 53952 | 129 | |
| stomach | 9 / 96619 | 93 | |
| testis | 25 / 330442 | 75 | |
| thymus | 5 / 81131 | 61 | |
| thyroid | 9 / 47473 | 189 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 8 / 52413 | 152 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 49 / 232878 | 210 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 216264_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 4.35 | |
| Adipocyte | 13.6 | |
| AdrenalCortex | 9.05 | |
| Adrenalgland | 3.85 | |
| Amygdala | 4.15 | |
| Appendix | 5.4 | |
| AtrioventricularNode | 3.2 | |
| BDCA4+_DentriticCells | 4.4 | |
| Bonemarrow | 3.9 | |
| BronchialEpithelialCells | 3.95 | |
| CD105+_Endothelial | 4.05 | |
| CD14+_Monocytes | 4.25 | |
| CD19+_BCells(neg._sel.) | 4.25 | |
| CD33+_Myeloid | 5.15 | |
| CD34+ | 5.5 | |
| CD4+_Tcells | 4.1 | |
| CD56+_NKCells | 4.5 | |
| CD71+_EarlyErythroid | 3.65 | |
| CD8+_Tcells | 3.7 | |
| CardiacMyocytes | 10.35 | |
| Caudatenucleus | 3.6 | |
| Cerebellum | 3.2 | |
| CerebellumPeduncles | 4.55 | |
| CiliaryGanglion | 3 | |
| CingulateCortex | 4.05 | |
| Colorectaladenocarcinoma | 31 | |
| DorsalRootGanglion | 3.5 | |
| FetalThyroid | 67.05 | |
| Fetalbrain | 3.95 | |
| Fetalliver | 3.45 | |
| Fetallung | 67.55 | |
| GlobusPallidus | 2.85 | |
| Heart | 76.25 | |
| Hypothalamus | 4.7 | |
| Kidney | 3.9 | |
| Leukemia_chronicMyelogenousK-562 | 4.55 | |
| Leukemia_promyelocytic-HL-60 | 3.5 | |
| Leukemialymphoblastic(MOLT-4) | 3.15 | |
| Liver | 66.75 | |
| Lung | 202.95 | |
| Lymphnode | 8.7 | |
| Lymphoma_burkitts(Daudi) | 5 | |
| Lymphoma_burkitts(Raji) | 5.55 | |
| MedullaOblongata | 3.55 | |
| OccipitalLobe | 3.55 | |
| OlfactoryBulb | 41.05 | |
| Ovary | 4.5 | |
| Pancreas | 4.5 | |
| PancreaticIslet | 7.9 | |
| ParietalLobe | 4.2 | |
| Pituitary | 4.6 | |
| Placenta | 96.4 | |
| Pons | 3.8 | |
| PrefrontalCortex | 5.1 | |
| Prostate | 104.75 | |
| Salivarygland | 3.2 | |
| SkeletalMuscle | 4.55 | |
| Skin | 3.95 | |
| SmoothMuscle | 88.8 | |
| Spinalcord | 4.35 | |
| SubthalamicNucleus | 3.6 | |
| SuperiorCervicalGanglion | 4.65 | |
| TemporalLobe | 3.65 | |
| Testis | 3.5 | |
| TestisGermCell | 11.2 | |
| TestisIntersitial | 3.95 | |
| TestisLeydigCell | 4 | |
| TestisSeminiferousTubule | 3.65 | |
| Thalamus | 4.1 | |
| Thymus | 3.45 | |
| Thyroid | 43.5 | |
| Tongue | 8.5 | |
| Tonsil | 4.1 | |
| Trachea | 3.6 | |
| TrigeminalGanglion | 9.65 | |
| Uterus | 131.95 | |
| UterusCorpus | 6.75 | |
| WholeBlood | 4.25 | |
| Wholebrain | 3.35 | |
| colon | 4 | |
| pineal_day | 5.06 | |
| pineal_night | 4.94 | |
| retina | 45.6 | |
| small_intestine | 3.95 | |
- Probe name: CUST_16814_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 6.17 ± 0.38 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.55 ± 0.15 | |
| Basal Part of Pons | 6.17 ± 0.5 | |
| Cerebellar Cortex | 6.35 ± 0.32 | |
| Cerebellar Nuclei | 6.76 ± 0.34 | |
| Claustrum | 5.78 ± 0.65 | |
| Epithalamus | 7.24 ± 0.45 | |
| Frontal Lobe | 6.49 ± 0.46 | |
| Globus Pallidus | 7.47 ± 0.29 | |
| Hypothalamus | 6.3 ± 0.52 | |
| Insula | 6.51 ± 0.3 | |
| Limbic Lobe | 6.27 ± 0.55 | |
| Mesencephalon | 6.59 ± 0.53 | |
| Myelencephalon | 6.62 ± 0.41 | |
| Occipital Lobe | 6.68 ± 0.59 | |
| Parietal Lobe | 6.34 ± 0.41 | |
| Pontine Tegmentum | 6.6 ± 0.56 | |
| Striatum | 7.31 ± 0.43 | |
| Subthalamus | 6.61 ± 0.48 | |
| Temporal Lobe | 6.39 ± 0.35 | |
| Thalamus | 6.78 ± 0.41 | |
| White Matter | 6.33 ± 0.75 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Lamb2 | CB | Cerebellum | 3.76 | |
| 7.57 | | |||
| Lamb2 | CTX | Cerebral cortex | 7.07 | |
| 7.37 | | |||
| Lamb2 | HIP | Hippocampal region | 11.16 | |
| 14.52 | | |||
| Lamb2 | HPF | Hippocampal formation | 12.08 | |
| 14.1 | | |||
| Lamb2 | HY | Hypothalamus | 8.45 | |
| 9.05 | | |||
| Lamb2 | LSX | Lateral septal complex | 3.13 | |
| 4.46 | | |||
| Lamb2 | MB | Midbrain | 6.12 | |
| 8.94 | | |||
| Lamb2 | MY | Medulla | 7.44 | |
| 12.63 | | |||
| Lamb2 | OLF | Olfactory bulb | 11.22 | |
| 10.55 | | |||
| Lamb2 | P | Pons | 9.27 | |
| 14.9 | | |||
| Lamb2 | PAL | Pallidum | 5.57 | |
| 7.31 | | |||
| Lamb2 | RHP | Retrohippocampal region | 14.16 | |
| 13.77 | | |||
| Lamb2 | sAMY | Striatum-like amygdalar nuclei | 5.54 | |
| 5.47 | | |||
| Lamb2 | STR | Striatum | 5.48 | |
| 5.89 | | |||
| Lamb2 | STRd | Striatum dorsal region | 5.94 | |
| 6.6 | | |||
| Lamb2 | STRv | Striatum ventral region | 6.13 | |
| 5.37 | | |||
| Lamb2 | TH | Thalamus | 5.31 | |
| 7.11 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| LAMB2_HUMAN_0 | 1 | 0 | 0 | GRGQPLPWELR | PRIDE |
| LAMB2_HUMAN_1720 | 11 | 1720 | 1730 | KAQGVLAAQAR | PRIDE |
| LAMB2_HUMAN_724 | 17 | 724 | 740 | VLVLEMFSGGDAAALER | PRIDE |
| PAp00039703 | 23 | 1010 | 1032 | CLHHTEGPHCAHCKPGFHGQAAR | Peptide Atlas |