AutismKB 2.0

Annotation Detail for LAMP1


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Basic Information Top
Gene Symbol:LAMP1 ( CD107a,LAMPA,LGP120 )
Gene Full Name: lysosomal-associated membrane protein 1
Band: 13q34
Quick LinksEntrez ID:3916; OMIM: 153330; Uniprot ID:LAMP1_HUMAN; ENSEMBL ID: ENSG00000185896; HGNC ID: 6499
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst9 / 62319144
fetus35 / 56401262
neonate5 / 31097160
infant3 / 23620127
juvenile9 / 55556161
adult309 / 1939121159
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma42 / 174752403
breast (mammary gland) tumor12 / 94178127
cervical tumor11 / 34366320
chondrosarcoma14 / 82823169
colorectal tumor26 / 114246227
esophageal tumor3 / 17290173
gastrointestinal tumor35 / 119369293
germ cell tumor26 / 26384598
glioma17 / 106883159
head and neck tumor8 / 13630258
kidney tumor17 / 68959246
leukemia11 / 95842114
liver tumor11 / 96359114
lung tumor18 / 103127174
lymphoma6 / 7175583
non-neoplasia16 / 97250164
normal321 / 336030795
ovarian tumor14 / 76682182
pancreatic tumor43 / 104616411
primitive neuroectodermal tumor of the CNS14 / 125680111
prostate cancer13 / 102680126
retinoblastoma1 / 4635621
skin tumor40 / 124949320
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor15 / 90257166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue6 / 13106457
adrenal gland5 / 33197150
ascites1 / 4001524
bladder43 / 297571445
blood14 / 123478113
bone12 / 71655167
bone marrow2 / 4880140
brain82 / 110098974
cervix13 / 48171269
connective tissue11 / 14925573
ear1 / 1621261
embryonic tissue21 / 21572297
esophagus3 / 20209148
eye26 / 211054123
heart17 / 89626189
intestine52 / 234472221
kidney30 / 211777141
larynx2 / 2414582
liver15 / 20774372
lung53 / 336974157
lymph5 / 44270112
lymph node10 / 91610109
mammary gland22 / 153271143
mouth3 / 6705244
muscle1 / 1077159
nerve7 / 15768443
ovary30 / 102051293
pancreas63 / 214812293
parathyroid3 / 20539146
pharynx3 / 4132872
pituitary gland3 / 16585180
placenta42 / 280825149
prostate30 / 189345158
salivary gland0 / 201550 
skin47 / 210574223
spleen4 / 5395274
stomach40 / 96619413
testis20 / 33044260
thymus4 / 8113149
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus21 / 23287890
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201553_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1113.95
Adipocyte2311.65
AdrenalCortex1360.9
Adrenalgland1092.1
Amygdala1930.05
Appendix669.3
AtrioventricularNode442
BDCA4+_DentriticCells3285
Bonemarrow587.4
BronchialEpithelialCells1619.6
CD105+_Endothelial2443.45
CD14+_Monocytes2758.45
CD19+_BCells(neg._sel.)1921.55
CD33+_Myeloid4890.7
CD34+2884.3
CD4+_Tcells1995.95
CD56+_NKCells5348.75
CD71+_EarlyErythroid662.25
CD8+_Tcells1905.95
CardiacMyocytes1596.4
Caudatenucleus1499.5
Cerebellum726.6
CerebellumPeduncles880.15
CiliaryGanglion458.15
CingulateCortex1292.1
Colorectaladenocarcinoma1462
DorsalRootGanglion843.9
FetalThyroid2953.7
Fetalbrain661
Fetalliver483.3
Fetallung1457.35
GlobusPallidus420.3
Heart1315.75
Hypothalamus3862.05
Kidney2245.6
Leukemia_chronicMyelogenousK-562226
Leukemia_promyelocytic-HL-60188.1
Leukemialymphoblastic(MOLT-4)347.55
Liver3688.2
Lung5930.5
Lymphnode1717.8
Lymphoma_burkitts(Daudi)339.45
Lymphoma_burkitts(Raji)262.1
MedullaOblongata1125.45
OccipitalLobe1453.75
OlfactoryBulb3007.9
Ovary537.5
Pancreas2877
PancreaticIslet2574.75
ParietalLobe1561.4
Pituitary2062.65
Placenta4324.9
Pons515.25
PrefrontalCortex3217.95
Prostate4635.95
Salivarygland1240.85
SkeletalMuscle183.15
Skin1027.65
SmoothMuscle3525.25
Spinalcord4239.8
SubthalamicNucleus685.9
SuperiorCervicalGanglion322.9
TemporalLobe450.85
Testis3585.6
TestisGermCell2282.6
TestisIntersitial1557.2
TestisLeydigCell1264.75
TestisSeminiferousTubule1657.4
Thalamus1851.8
Thymus1870
Thyroid4922.1
Tongue1784.4
Tonsil791
Trachea1449.75
TrigeminalGanglion715.95
Uterus2485.4
UterusCorpus1136.35
WholeBlood2448.9
Wholebrain2639.95
colon1943.3
pineal_day4524.72
pineal_night4679.32
retina2912.6
small_intestine1831.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P304549
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.22 ± 0.63
Basal Forebrain5.47 ± 0.34
Basal Part of Pons5.73 ± 0.43
Cerebellar Cortex5.34 ± 0.29
Cerebellar Nuclei5.85 ± 0.5
Claustrum4.83 ± 0.52
Epithalamus5.85 ± 0.49
Frontal Lobe5.62 ± 0.46
Globus Pallidus6.37 ± 0.54
Hypothalamus5.37 ± 0.54
Insula5.36 ± 0.39
Limbic Lobe5.35 ± 0.43
Mesencephalon5.35 ± 0.48
Myelencephalon5.55 ± 0.5
Occipital Lobe5.44 ± 0.4
Parietal Lobe5.37 ± 0.54
Pontine Tegmentum5.55 ± 0.44
Striatum5.65 ± 0.39
Subthalamus5.61 ± 0.27
Temporal Lobe5.45 ± 0.34
Thalamus5.76 ± 0.52
White Matter7.5 ± 0.15
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lamp1CBCerebellum99.46
100
Lamp1CTXCerebral cortex100
100
Lamp1HIPHippocampal region92.66
100
Lamp1HPFHippocampal formation100
100
Lamp1HYHypothalamus100
100
Lamp1LSXLateral septal complex100
100
Lamp1MBMidbrain100
100
Lamp1MYMedulla100
100
Lamp1OLFOlfactory bulb100
100
Lamp1PPons100
100
Lamp1PALPallidum100
100
Lamp1RHPRetrohippocampal region100
100
Lamp1sAMYStriatum-like amygdalar nuclei100
100
Lamp1STRStriatum99.01
97.58
Lamp1STRdStriatum dorsal region96.36
97.8
Lamp1STRvStriatum ventral region78.67
69.35
Lamp1THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
LAMP1_HUMAN_0 0 0 0 FFLQGIQLNTILPDAR PRIDE
LAMP1_HUMAN_0 0 0 0 TVESITDIR PRIDE
LAMP1_HUMAN_136 9 136 144 TVESITDIR PRIDE
LAMP1_HUMAN_137 9 137 145 TVESITDIR PRIDE
LAMP1_HUMAN_297 16 297 312 FFLQGIQLNTILPDAR PRIDE
LAMP1_HUMAN_297 21 297 317 FFLQGIQLNTILPDARDPAFK PRIDE
LAMP1_HUMAN_298 21 298 318 FFLQGIQLNTILPDARDPAFK PRIDE
LAMP1_HUMAN_325 11 325 335 ALQATVGNSYK PRIDE
LAMP1_HUMAN_326 11 326 336 ALQATVGNSYK PRIDE
PAp00000949 25 191 215 CEQDRPSPTTAPPAPPSPSPSPVPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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