AutismKB 2.0

Annotation Detail for LGALS2


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Basic Information Top
Gene Symbol:LGALS2 ( HL14,MGC75071 )
Gene Full Name: lectin, galactoside-binding, soluble, 2
Band: 22q13.1
Quick LinksEntrez ID:3957; OMIM: 150571; Uniprot ID:LEG2_HUMAN; ENSEMBL ID: ENSG00000100079; HGNC ID: 6562
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult11 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal21 / 33603076
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain0 / 11009890 
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart1 / 8962611
intestine0 / 2344720 
kidney8 / 21177737
larynx0 / 241450 
liver1 / 2077434
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208450_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.95
Adipocyte4.9
AdrenalCortex5.55
Adrenalgland4.3
Amygdala5.1
Appendix5.15
AtrioventricularNode5.75
BDCA4+_DentriticCells304.5
Bonemarrow5.1
BronchialEpithelialCells4.8
CD105+_Endothelial5.5
CD14+_Monocytes373.8
CD19+_BCells(neg._sel.)5.45
CD33+_Myeloid969.3
CD34+6.2
CD4+_Tcells5.3
CD56+_NKCells5.95
CD71+_EarlyErythroid4.7
CD8+_Tcells4.65
CardiacMyocytes6.2
Caudatenucleus4.45
Cerebellum4.05
CerebellumPeduncles5.8
CiliaryGanglion5.75
CingulateCortex5.2
Colorectaladenocarcinoma4.95
DorsalRootGanglion4.05
FetalThyroid4.85
Fetalbrain4.85
Fetalliver4.35
Fetallung3.9
GlobusPallidus3.75
Heart6.6
Hypothalamus5.35
Kidney191.6
Leukemia_chronicMyelogenousK-5624.5
Leukemia_promyelocytic-HL-604.4
Leukemialymphoblastic(MOLT-4)3.9
Liver6.7
Lung5.4
Lymphnode5.45
Lymphoma_burkitts(Daudi)6.55
Lymphoma_burkitts(Raji)7
MedullaOblongata4.45
OccipitalLobe4.45
OlfactoryBulb3.9
Ovary3.85
Pancreas78.7
PancreaticIslet7.6
ParietalLobe5.4
Pituitary5.75
Placenta5
Pons4.8
PrefrontalCortex6.1
Prostate5.7
Salivarygland4.1
SkeletalMuscle6.2
Skin4.05
SmoothMuscle5.55
Spinalcord5.3
SubthalamicNucleus4.75
SuperiorCervicalGanglion6.15
TemporalLobe6.95
Testis4.2
TestisGermCell4.05
TestisIntersitial4.15
TestisLeydigCell4.95
TestisSeminiferousTubule4.25
Thalamus5.1
Thymus3.9
Thyroid6.1
Tongue5.05
Tonsil7.55
Trachea4.15
TrigeminalGanglion5.4
Uterus4
UterusCorpus4.65
WholeBlood212.25
Wholebrain4.1
colon5
pineal_day6.12
pineal_night6
retina6
small_intestine109.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14333_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.98 ± 1.08
Basal Forebrain1.39 ± 0.2
Basal Part of Pons1.14 ± 0.39
Cerebellar Cortex1.36 ± 0.81
Cerebellar Nuclei1.79 ± 0.7
Claustrum2.27 ± 0.8
Epithalamus1.14 ± 0.66
Frontal Lobe1.6 ± 0.79
Globus Pallidus2.21 ± 0.47
Hypothalamus1.64 ± 0.65
Insula1.76 ± 0.94
Limbic Lobe1.55 ± 0.7
Mesencephalon1.72 ± 0.82
Myelencephalon1.57 ± 0.74
Occipital Lobe1.43 ± 0.77
Parietal Lobe1.4 ± 0.77
Pontine Tegmentum1.52 ± 0.65
Striatum1.45 ± 0.54
Subthalamus1.53 ± 0.64
Temporal Lobe1.37 ± 0.7
Thalamus1.55 ± 0.76
White Matter1.87 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lgals2CBCerebellum0
0
Lgals2CTXCerebral cortex0
0
Lgals2HIPHippocampal region0
0
Lgals2HPFHippocampal formation0
0
Lgals2HYHypothalamus0
0
Lgals2LSXLateral septal complex0
0
Lgals2MBMidbrain0
0
Lgals2MYMedulla0
0
Lgals2OLFOlfactory bulb0
0
Lgals2PPons0
0
Lgals2PALPallidum0
0
Lgals2RHPRetrohippocampal region0
0
Lgals2sAMYStriatum-like amygdalar nuclei0
0
Lgals2STRStriatum0
0
Lgals2STRdStriatum dorsal region0
0
Lgals2STRvStriatum ventral region0
0
Lgals2THThalamus0
0
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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