AutismKB 2.0

Annotation Detail for LGALS3BP


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Basic Information Top
Gene Symbol:LGALS3BP ( 90K,BTBD17B,MAC-2-BP )
Gene Full Name: lectin, galactoside-binding, soluble, 3 binding protein
Band: 17q25
Quick LinksEntrez ID:3959; OMIM: 600626; Uniprot ID:LG3BP_HUMAN; ENSEMBL ID: ENSG00000108679; HGNC ID: 6564
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst5 / 6231980
fetus41 / 56401272
neonate0 / 310970 
infant5 / 23620211
juvenile6 / 55556107
adult629 / 1939121324
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor6 / 12794468
bladder carcinoma1 / 1747557
breast (mammary gland) tumor21 / 94178222
cervical tumor7 / 34366203
chondrosarcoma29 / 82823350
colorectal tumor123 / 1142461076
esophageal tumor22 / 172901272
gastrointestinal tumor51 / 119369427
germ cell tumor18 / 26384568
glioma39 / 106883364
head and neck tumor36 / 136302264
kidney tumor24 / 68959348
leukemia39 / 95842406
liver tumor18 / 96359186
lung tumor77 / 103127746
lymphoma2 / 7175527
non-neoplasia8 / 9725082
normal494 / 3360307147
ovarian tumor95 / 766821238
pancreatic tumor74 / 104616707
primitive neuroectodermal tumor of the CNS76 / 125680604
prostate cancer19 / 102680185
retinoblastoma0 / 463560 
skin tumor106 / 124949848
soft tissue/muscle tissue tumor26 / 125191207
uterine tumor34 / 90257376
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland7 / 33197210
ascites20 / 40015499
bladder1 / 2975733
blood4 / 12347832
bone22 / 71655307
bone marrow103 / 488012110
brain154 / 1100989139
cervix10 / 48171207
connective tissue15 / 149255100
ear0 / 162120 
embryonic tissue19 / 21572288
esophagus22 / 202091088
eye35 / 211054165
heart6 / 8962666
intestine142 / 234472605
kidney33 / 211777155
larynx3 / 24145124
liver27 / 207743129
lung126 / 336974373
lymph1 / 4427022
lymph node38 / 91610414
mammary gland38 / 153271247
mouth13 / 67052193
muscle17 / 107715157
nerve5 / 15768317
ovary99 / 102051970
pancreas80 / 214812372
parathyroid1 / 2053948
pharynx3 / 4132872
pituitary gland10 / 16585602
placenta162 / 280825576
prostate22 / 189345116
salivary gland14 / 20155694
skin114 / 210574541
spleen7 / 53952129
stomach43 / 96619445
testis36 / 330442108
thymus4 / 8113149
thyroid14 / 47473294
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus60 / 232878257
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200923_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.9
Adipocyte506.45
AdrenalCortex180.35
Adrenalgland454.65
Amygdala43.65
Appendix80.1
AtrioventricularNode55.25
BDCA4+_DentriticCells6
Bonemarrow5.45
BronchialEpithelialCells322
CD105+_Endothelial27.6
CD14+_Monocytes8.7
CD19+_BCells(neg._sel.)5.85
CD33+_Myeloid11.1
CD34+25.95
CD4+_Tcells59.7
CD56+_NKCells6.4
CD71+_EarlyErythroid8.95
CD8+_Tcells54.65
CardiacMyocytes120.6
Caudatenucleus56.2
Cerebellum51.65
CerebellumPeduncles57.05
CiliaryGanglion64.8
CingulateCortex53.9
Colorectaladenocarcinoma223.5
DorsalRootGanglion103.85
FetalThyroid273.4
Fetalbrain12.25
Fetalliver19.85
Fetallung73
GlobusPallidus12.65
Heart1245.1
Hypothalamus157.75
Kidney155.4
Leukemia_chronicMyelogenousK-56241.3
Leukemia_promyelocytic-HL-6032.8
Leukemialymphoblastic(MOLT-4)166.35
Liver167.65
Lung1067.6
Lymphnode67.6
Lymphoma_burkitts(Daudi)25.95
Lymphoma_burkitts(Raji)101.3
MedullaOblongata55.05
OccipitalLobe60.1
OlfactoryBulb165
Ovary63.7
Pancreas117.55
PancreaticIslet140.45
ParietalLobe86.9
Pituitary425.2
Placenta540.35
Pons38
PrefrontalCortex64.7
Prostate698.2
Salivarygland89.05
SkeletalMuscle21.7
Skin7.15
SmoothMuscle423.85
Spinalcord330.7
SubthalamicNucleus15.85
SuperiorCervicalGanglion56.7
TemporalLobe10.6
Testis219.8
TestisGermCell343.7
TestisIntersitial102.3
TestisLeydigCell105.4
TestisSeminiferousTubule131.2
Thalamus134.2
Thymus298.95
Thyroid640.35
Tongue67.45
Tonsil74.25
Trachea326.1
TrigeminalGanglion99
Uterus268.65
UterusCorpus71.45
WholeBlood6.5
Wholebrain68.35
colon601.4
pineal_day33.14
pineal_night80.36
retina393.55
small_intestine404.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P154321
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.89 ± 1.04
Basal Forebrain1.34 ± 0.28
Basal Part of Pons0.99 ± 0.42
Cerebellar Cortex1.16 ± 0.72
Cerebellar Nuclei1.61 ± 0.85
Claustrum2.25 ± 0.92
Epithalamus1.18 ± 0.88
Frontal Lobe1.3 ± 0.72
Globus Pallidus2.39 ± 0.73
Hypothalamus1.59 ± 0.7
Insula1.14 ± 0.79
Limbic Lobe1.35 ± 0.75
Mesencephalon1.56 ± 0.77
Myelencephalon1.49 ± 0.77
Occipital Lobe1.53 ± 0.75
Parietal Lobe1.41 ± 0.89
Pontine Tegmentum1.5 ± 0.75
Striatum1.7 ± 0.72
Subthalamus1.59 ± 0.45
Temporal Lobe1.34 ± 0.8
Thalamus1.45 ± 0.65
White Matter2.8 ± 0.1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lgals3bpCBCerebellum4.97
7.31
Lgals3bpCTXCerebral cortex1.63
2.1
Lgals3bpHIPHippocampal region2.19
7.88
Lgals3bpHPFHippocampal formation1.58
5.51
Lgals3bpHYHypothalamus0.73
0.66
Lgals3bpLSXLateral septal complex0.09
0.05
Lgals3bpMBMidbrain0.8
1.46
Lgals3bpMYMedulla2.11
4.03
Lgals3bpOLFOlfactory bulb6.13
6.6
Lgals3bpPPons1.53
1.86
Lgals3bpPALPallidum0.23
0.18
Lgals3bpRHPRetrohippocampal region0.55
1.72
Lgals3bpsAMYStriatum-like amygdalar nuclei0.03
0
Lgals3bpSTRStriatum1.17
1.73
Lgals3bpSTRdStriatum dorsal region1.66
2.72
Lgals3bpSTRvStriatum ventral region0.7
0.51
Lgals3bpTHThalamus1.07
1.8
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
LG3BP_HUMAN_138 14 138 151 ELSEALGQIFDSQR PRIDE
LG3BP_HUMAN_311 13 311 323 SDLAVPSELALLK PRIDE
LG3BP_HUMAN_37 6 37 42 VEIFYR PRIDE
LG3BP_HUMAN_64 13 64 76 ALGFENATQALGR PRIDE
PAp00007498 16 555 570 STSSFPCPAGHFNGFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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