Annotation Detail for LIG1
Basic Information Top
| Gene Symbol: | LIG1 ( MGC117397,MGC130025 ) |
|---|---|
| Gene Full Name: | ligase I, DNA, ATP-dependent |
| Band: | 19q13.33 |
| Quick Links | Entrez ID:3978; OMIM: 126391; Uniprot ID:DNLI1_HUMAN; ENSEMBL ID: ENSG00000105486; HGNC ID: 6598 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.1770
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 5 / 70761 | 70 |  |
| blastocyst | 13 / 62319 | 208 |  |
| fetus | 47 / 564012 | 83 | |
| neonate | 1 / 31097 | 32 |  |
| infant | 0 / 23620 | 0 | |
| juvenile | 5 / 55556 | 89 | |
| adult | 114 / 1939121 | 58 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 7 / 94178 | 74 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 4 / 82823 | 48 | |
| colorectal tumor | 14 / 114246 | 122 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 13 / 119369 | 108 | |
| germ cell tumor | 28 / 263845 | 106 | |
| glioma | 5 / 106883 | 46 | |
| head and neck tumor | 8 / 136302 | 58 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 18 / 95842 | 187 | |
| liver tumor | 13 / 96359 | 134 | |
| lung tumor | 5 / 103127 | 48 | |
| lymphoma | 10 / 71755 | 139 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 192 / 3360307 | 57 | |
| ovarian tumor | 6 / 76682 | 78 | |
| pancreatic tumor | 10 / 104616 | 95 | |
| primitive neuroectodermal tumor of the CNS | 8 / 125680 | 63 | |
| prostate cancer | 5 / 102680 | 48 | |
| retinoblastoma | 9 / 46356 | 194 | |
| skin tumor | 11 / 124949 | 88 | |
| soft tissue/muscle tissue tumor | 7 / 125191 | 55 | |
| uterine tumor | 5 / 90257 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 5 / 40015 | 124 | |
| bladder | 0 / 29757 | 0 | |
| blood | 16 / 123478 | 129 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 3 / 48801 | 61 | |
| brain | 51 / 1100989 | 46 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 25 / 215722 | 115 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 17 / 211054 | 80 | |
| heart | 5 / 89626 | 55 | |
| intestine | 22 / 234472 | 93 | |
| kidney | 5 / 211777 | 23 | |
| larynx | 4 / 24145 | 165 | |
| liver | 16 / 207743 | 77 | |
| lung | 15 / 336974 | 44 | |
| lymph | 7 / 44270 | 158 | |
| lymph node | 4 / 91610 | 43 | |
| mammary gland | 8 / 153271 | 52 | |
| mouth | 3 / 67052 | 44 | |
| muscle | 16 / 107715 | 148 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 6 / 102051 | 58 | |
| pancreas | 16 / 214812 | 74 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 21 / 280825 | 74 | |
| prostate | 9 / 189345 | 47 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 12 / 210574 | 56 | |
| spleen | 2 / 53952 | 37 | |
| stomach | 5 / 96619 | 51 | |
| testis | 32 / 330442 | 96 | |
| thymus | 19 / 81131 | 234 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 2 / 16999 | 117 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 2 / 13680 | 146 | |
| uterus | 8 / 232878 | 34 | |
| vascular | 5 / 51780 | 96 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 202726_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 113.2 | |
| Adipocyte | 3.95 |  |
| AdrenalCortex | 4.25 | |
| Adrenalgland | 3.4 | |
| Amygdala | 4.25 | |
| Appendix | 4.1 | |
| AtrioventricularNode | 3.05 | |
| BDCA4+_DentriticCells | 6.45 | |
| Bonemarrow | 4.05 | |
| BronchialEpithelialCells | 4 | |
| CD105+_Endothelial | 117.5 | |
| CD14+_Monocytes | 4.3 | |
| CD19+_BCells(neg._sel.) | 9.55 | |
| CD33+_Myeloid | 5.25 | |
| CD34+ | 46.4 | |
| CD4+_Tcells | 24.75 | |
| CD56+_NKCells | 10.65 | |
| CD71+_EarlyErythroid | 93.25 | |
| CD8+_Tcells | 21.25 | |
| CardiacMyocytes | 5.2 | |
| Caudatenucleus | 3.6 | |
| Cerebellum | 3.3 | |
| CerebellumPeduncles | 4.6 | |
| CiliaryGanglion | 2.8 | |
| CingulateCortex | 4.15 | |
| Colorectaladenocarcinoma | 6.95 | |
| DorsalRootGanglion | 3.05 | |
| FetalThyroid | 4 | |
| Fetalbrain | 4.15 | |
| Fetalliver | 3.55 | |
| Fetallung | 3.45 | |
| GlobusPallidus | 2.9 | |
| Heart | 5.1 | |
| Hypothalamus | 4.5 | |
| Kidney | 3.25 | |
| Leukemia_chronicMyelogenousK-562 | 7.7 | |
| Leukemia_promyelocytic-HL-60 | 6.4 | |
| Leukemialymphoblastic(MOLT-4) | 56.4 | |
| Liver | 5.3 | |
| Lung | 4.45 | |
| Lymphnode | 4.75 | |
| Lymphoma_burkitts(Daudi) | 25.05 | |
| Lymphoma_burkitts(Raji) | 6 | |
| MedullaOblongata | 3.7 | |
| OccipitalLobe | 3.65 | |
| OlfactoryBulb | 3.2 | |
| Ovary | 2.65 | |
| Pancreas | 3.25 | |
| PancreaticIslet | 4.35 | |
| ParietalLobe | 4.3 | |
| Pituitary | 4.75 | |
| Placenta | 4.4 | |
| Pons | 3.85 | |
| PrefrontalCortex | 5.05 | |
| Prostate | 4.8 | |
| Salivarygland | 3.2 | |
| SkeletalMuscle | 4.65 | |
| Skin | 3.05 | |
| SmoothMuscle | 4.65 | |
| Spinalcord | 4.35 | |
| SubthalamicNucleus | 3.65 | |
| SuperiorCervicalGanglion | 4.5 | |
| TemporalLobe | 3.65 | |
| Testis | 3.5 | |
| TestisGermCell | 4.85 | |
| TestisIntersitial | 3.4 | |
| TestisLeydigCell | 4.05 | |
| TestisSeminiferousTubule | 3.85 | |
| Thalamus | 4.15 | |
| Thymus | 4.65 | |
| Thyroid | 5.2 | |
| Tongue | 3.9 | |
| Tonsil | 4.05 | |
| Trachea | 3.4 | |
| TrigeminalGanglion | 4 | |
| Uterus | 3.35 | |
| UterusCorpus | 3.65 | |
| WholeBlood | 4.5 | |
| Wholebrain | 3.45 | |
| colon | 4.2 | |
| pineal_day | 5.44 | |
| pineal_night | 5 | |
| retina | 4.925 | |
| small_intestine | 3.95 | |
- Probe name: CUST_15046_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.63 ± 0.28 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.77 ± 0.31 | |
| Basal Part of Pons | 6.36 ± 0.21 | |
| Cerebellar Cortex | 6.12 ± 0.3 | |
| Cerebellar Nuclei | 6.2 ± 0.42 | |
| Claustrum | 5.36 ± 0.6 | |
| Epithalamus | 6 ± 0.6 | |
| Frontal Lobe | 5.77 ± 0.41 | |
| Globus Pallidus | 5.78 ± 0.23 | |
| Hypothalamus | 5.81 ± 0.7 | |
| Insula | 5.86 ± 0.36 | |
| Limbic Lobe | 5.56 ± 0.43 | |
| Mesencephalon | 5.76 ± 0.39 | |
| Myelencephalon | 5.8 ± 0.44 | |
| Occipital Lobe | 5.56 ± 0.38 | |
| Parietal Lobe | 5.68 ± 0.34 | |
| Pontine Tegmentum | 5.62 ± 0.38 | |
| Striatum | 5.48 ± 0.34 | |
| Subthalamus | 5.99 ± 0.35 | |
| Temporal Lobe | 5.94 ± 0.37 | |
| Thalamus | 5.71 ± 0.39 | |
| White Matter | 6.68 ± 0.34 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Lig1 | CB | Cerebellum | 9.86 | |
| 12.25 | | |||
| Lig1 | CTX | Cerebral cortex | 32.93 | |
| 26.15 | | |||
| Lig1 | HIP | Hippocampal region | 28.37 | |
| 31.92 | | |||
| Lig1 | HPF | Hippocampal formation | 18.71 | |
| 18.23 | | |||
| Lig1 | HY | Hypothalamus | 35.99 | |
| 29.99 | | |||
| Lig1 | LSX | Lateral septal complex | 12.44 | |
| 9.78 | | |||
| Lig1 | MB | Midbrain | 19.03 | |
| 15.52 | | |||
| Lig1 | MY | Medulla | 34.18 | |
| 37.52 | | |||
| Lig1 | OLF | Olfactory bulb | 37.43 | |
| 31.46 | | |||
| Lig1 | P | Pons | 25.08 | |
| 24.78 | | |||
| Lig1 | PAL | Pallidum | 23.51 | |
| 20.13 | | |||
| Lig1 | RHP | Retrohippocampal region | 60.61 | |
| 48.76 | | |||
| Lig1 | sAMY | Striatum-like amygdalar nuclei | 45.17 | |
| 33.26 | | |||
| Lig1 | STR | Striatum | 17.74 | |
| 13.01 | | |||
| Lig1 | STRd | Striatum dorsal region | 35.74 | |
| 26.49 | | |||
| Lig1 | STRv | Striatum ventral region | 36.95 | |
| 25.22 | | |||
| Lig1 | TH | Thalamus | 19.97 | |
| 16.24 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| DNLI1_HUMAN_573 | 24 | 573 | 596 | AQIHALEGGEVKIFSRNQEDNTGK | PRIDE |
| PAp00008568 | 21 | 878 | 898 | VREDKQPEQATTSAQVACLYR | Peptide Atlas |