AutismKB 2.0

Annotation Detail for LIPE


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Basic Information Top
Gene Symbol:LIPE ( HSL,LHS )
Gene Full Name: lipase, hormone-sensitive
Band: 19q13.2
Quick LinksEntrez ID:3991; OMIM: 151750; Uniprot ID:LIPS_HUMAN; ENSEMBL ID: ENSG00000079435; HGNC ID: 6621
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus10 / 56401217
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult43 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma6 / 10688356
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal82 / 336030724
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue5 / 13106381
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone3 / 7165541
bone marrow0 / 488010 
brain37 / 110098933
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine4 / 23447217
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node4 / 9161043
mammary gland12 / 15327178
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis6 / 33044218
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213855_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.8
Adipocyte10.6
AdrenalCortex4.65
Adrenalgland3.75
Amygdala4.8
Appendix4.45
AtrioventricularNode3.4
BDCA4+_DentriticCells4.95
Bonemarrow4.35
BronchialEpithelialCells4.45
CD105+_Endothelial4.55
CD14+_Monocytes4.7
CD19+_BCells(neg._sel.)4.85
CD33+_Myeloid5.45
CD34+5.35
CD4+_Tcells5
CD56+_NKCells5.15
CD71+_EarlyErythroid4.1
CD8+_Tcells4.45
CardiacMyocytes5.75
Caudatenucleus4
Cerebellum3.65
CerebellumPeduncles5.05
CiliaryGanglion3
CingulateCortex4.55
Colorectaladenocarcinoma4.5
DorsalRootGanglion3.45
FetalThyroid4.3
Fetalbrain4.45
Fetalliver3.95
Fetallung3.8
GlobusPallidus3.15
Heart5.85
Hypothalamus4.95
Kidney3.5
Leukemia_chronicMyelogenousK-5624.05
Leukemia_promyelocytic-HL-603.95
Leukemialymphoblastic(MOLT-4)3.65
Liver5.9
Lung4.95
Lymphnode3.9
Lymphoma_burkitts(Daudi)5.65
Lymphoma_burkitts(Raji)6.3
MedullaOblongata4.15
OccipitalLobe4
OlfactoryBulb3.55
Ovary2.95
Pancreas3.6
PancreaticIslet4.75
ParietalLobe4.65
Pituitary5.25
Placenta4.7
Pons4.3
PrefrontalCortex5.65
Prostate5.2
Salivarygland3.5
SkeletalMuscle5.35
Skin3.5
SmoothMuscle5.1
Spinalcord4.8
SubthalamicNucleus4
SuperiorCervicalGanglion5.05
TemporalLobe4.05
Testis4
TestisGermCell3.85
TestisIntersitial3.7
TestisLeydigCell4.35
TestisSeminiferousTubule3.8
Thalamus4.55
Thymus3.6
Thyroid5.7
Tongue4.25
Tonsil4.35
Trachea3.75
TrigeminalGanglion4.3
Uterus3.7
UterusCorpus3.95
WholeBlood4.95
Wholebrain3.9
colon4.5
pineal_day5.58
pineal_night5.42
retina5.45
small_intestine4.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16129_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.14 ± 0.91
Basal Forebrain3.67 ± 0.62
Basal Part of Pons4.04 ± 0.81
Cerebellar Cortex3.43 ± 0.58
Cerebellar Nuclei4.41 ± 0.48
Claustrum3.15 ± 0.64
Epithalamus2.93 ± 0.85
Frontal Lobe3.41 ± 0.76
Globus Pallidus4.86 ± 0.35
Hypothalamus3.04 ± 0.58
Insula3.07 ± 0.46
Limbic Lobe3.03 ± 0.72
Mesencephalon3.47 ± 0.91
Myelencephalon3.5 ± 0.68
Occipital Lobe3.47 ± 0.81
Parietal Lobe3.4 ± 0.88
Pontine Tegmentum3.52 ± 0.57
Striatum3.86 ± 0.67
Subthalamus3.84 ± 0.67
Temporal Lobe3.19 ± 0.64
Thalamus3.84 ± 0.56
White Matter6.04 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
LipeCBCerebellum12.51
14.03
LipeCTXCerebral cortex10.87
7.07
LipeHIPHippocampal region6.61
5.74
LipeHPFHippocampal formation8.58
6.97
LipeHYHypothalamus5.65
3.91
LipeLSXLateral septal complex4.27
2.7
LipeMBMidbrain7.2
6.83
LipeMYMedulla13.31
12.09
LipeOLFOlfactory bulb26.67
20.09
LipePPons10.53
9.13
LipePALPallidum6.77
5.04
LipeRHPRetrohippocampal region12.17
8.79
LipesAMYStriatum-like amygdalar nuclei11.1
8.35
LipeSTRStriatum6.91
4.7
LipeSTRdStriatum dorsal region4.88
3.39
LipeSTRvStriatum ventral region12.71
7.47
LipeTHThalamus7.58
5.76
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
LIPS_HUMAN_166 29 166 194 REPSAPTESTSQETPEQSDKQTTPVQGAK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018