AutismKB 2.0

Annotation Detail for FADS3


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Basic Information Top
Gene Symbol:FADS3 ( CYB5RP,LLCDL3 )
Gene Full Name: fatty acid desaturase 3
Band: 11q12.2
Quick LinksEntrez ID:3995; OMIM: 606150; Uniprot ID:FADS3_HUMAN; ENSEMBL ID: ENSG00000221968; HGNC ID: 3576
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus27 / 56401247
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult68 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma7 / 8282384
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor6 / 26384522
glioma7 / 10688365
head and neck tumor5 / 13630236
kidney tumor4 / 6895958
leukemia8 / 9584283
liver tumor1 / 9635910
lung tumor3 / 10312729
lymphoma4 / 7175555
non-neoplasia1 / 9725010
normal133 / 336030739
ovarian tumor5 / 7668265
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor3 / 12494924
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood2 / 12347816
bone8 / 71655111
bone marrow2 / 4880140
brain41 / 110098937
cervix1 / 4817120
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye11 / 21105452
heart4 / 8962644
intestine5 / 23447221
kidney6 / 21177728
larynx2 / 2414582
liver4 / 20774319
lung8 / 33697423
lymph0 / 442700 
lymph node23 / 91610251
mammary gland1 / 1532716
mouth0 / 670520 
muscle7 / 10771564
nerve4 / 15768253
ovary7 / 10205168
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta16 / 28082556
prostate1 / 1893455
salivary gland0 / 201550 
skin6 / 21057428
spleen4 / 5395274
stomach0 / 966190 
testis3 / 3304429
thymus2 / 8113124
thyroid3 / 4747363
tonsil5 / 16999294
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204257_at
Cell line Expression level Expression bar
721_B_lymphoblasts15.95
Adipocyte277.2
AdrenalCortex136.55
Adrenalgland73.15
Amygdala106.25
Appendix77.05
AtrioventricularNode95.1
BDCA4+_DentriticCells20.7
Bonemarrow91.35
BronchialEpithelialCells223.2
CD105+_Endothelial81.9
CD14+_Monocytes13.55
CD19+_BCells(neg._sel.)329.9
CD33+_Myeloid25.95
CD34+106.85
CD4+_Tcells25.15
CD56+_NKCells35.9
CD71+_EarlyErythroid70.35
CD8+_Tcells20.85
CardiacMyocytes116.9
Caudatenucleus56.1
Cerebellum48.1
CerebellumPeduncles79.6
CiliaryGanglion64.25
CingulateCortex109.55
Colorectaladenocarcinoma146.55
DorsalRootGanglion116.1
FetalThyroid29.5
Fetalbrain111.95
Fetalliver75
Fetallung42.85
GlobusPallidus53
Heart349.65
Hypothalamus72.4
Kidney61.5
Leukemia_chronicMyelogenousK-562159.7
Leukemia_promyelocytic-HL-6054.8
Leukemialymphoblastic(MOLT-4)46.2
Liver92.8
Lung116.15
Lymphnode89.55
Lymphoma_burkitts(Daudi)121.9
Lymphoma_burkitts(Raji)727.25
MedullaOblongata73.1
OccipitalLobe92.4
OlfactoryBulb213.85
Ovary60.5
Pancreas55.65
PancreaticIslet72.7
ParietalLobe82.25
Pituitary82.8
Placenta334.4
Pons91.6
PrefrontalCortex116
Prostate53
Salivarygland56.95
SkeletalMuscle54.95
Skin54.3
SmoothMuscle107.95
Spinalcord78.5
SubthalamicNucleus61.7
SuperiorCervicalGanglion57.9
TemporalLobe97.2
Testis52.55
TestisGermCell37.05
TestisIntersitial26.15
TestisLeydigCell43.4
TestisSeminiferousTubule56.15
Thalamus81.05
Thymus32.6
Thyroid70.1
Tongue60.35
Tonsil92.85
Trachea46.65
TrigeminalGanglion117.95
Uterus54.6
UterusCorpus47.45
WholeBlood12.9
Wholebrain92.8
colon41.5
pineal_day95.46
pineal_night116
retina168.075
small_intestine48.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10852_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.72 ± 0.41
Basal Forebrain5.5 ± 0.4
Basal Part of Pons4.99 ± 0.58
Cerebellar Cortex4.99 ± 0.49
Cerebellar Nuclei4.24 ± 0.33
Claustrum5.89 ± 0.47
Epithalamus5.14 ± 0.38
Frontal Lobe5.46 ± 0.46
Globus Pallidus4.78 ± 0.42
Hypothalamus5.39 ± 0.28
Insula5.5 ± 0.42
Limbic Lobe5.44 ± 0.48
Mesencephalon5.29 ± 0.54
Myelencephalon5.26 ± 0.62
Occipital Lobe4.62 ± 0.49
Parietal Lobe5.25 ± 0.52
Pontine Tegmentum5.29 ± 0.6
Striatum4.53 ± 0.65
Subthalamus4.78 ± 0.61
Temporal Lobe5.42 ± 0.53
Thalamus5.04 ± 0.49
White Matter5.03 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fads3CBCerebellum11.3
14.47
Fads3CTXCerebral cortex40.86
29.18
Fads3HIPHippocampal region18.97
18.22
Fads3HPFHippocampal formation24.76
21.29
Fads3HYHypothalamus19.75
14.2
Fads3LSXLateral septal complex8.6
5.43
Fads3MBMidbrain19.27
16.75
Fads3MYMedulla34.37
37.62
Fads3OLFOlfactory bulb29.11
21.46
Fads3PPons25.12
24.43
Fads3PALPallidum23.19
19.27
Fads3RHPRetrohippocampal region35.83
26.62
Fads3sAMYStriatum-like amygdalar nuclei22.73
15.45
Fads3STRStriatum11.14
7.94
Fads3STRdStriatum dorsal region9.76
7.46
Fads3STRvStriatum ventral region10.53
6.48
Fads3THThalamus22.84
17.41
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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