AutismKB 2.0

Annotation Detail for FAM174B


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Basic Information Top
Gene Symbol:FAM174B ( MGC102891 )
Gene Full Name: family with sequence similarity 174, member B
Band: 15q26.1
Quick LinksEntrez ID:400451; OMIM: NA; Uniprot ID:F174B_HUMAN; ENSEMBL ID: ENSG00000185442; HGNC ID: 34339
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst3 / 6231948
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult54 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal76 / 336030722
ovarian tumor0 / 766820 
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer13 / 102680126
retinoblastoma0 / 463560 
skin tumor13 / 124949104
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder4 / 29757134
blood4 / 12347832
bone2 / 7165527
bone marrow0 / 488010 
brain13 / 110098911
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye11 / 21105452
heart1 / 8962611
intestine2 / 2344728
kidney1 / 2117774
larynx0 / 241450 
liver4 / 20774319
lung24 / 33697471
lymph0 / 442700 
lymph node3 / 9161032
mammary gland3 / 15327119
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas18 / 21481283
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta1 / 2808253
prostate16 / 18934584
salivary gland0 / 201550 
skin14 / 21057466
spleen0 / 539520 
stomach1 / 9661910
testis4 / 33044212
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221880_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.45
Adipocyte5.6
AdrenalCortex6.3
Adrenalgland4.75
Amygdala6.05
Appendix5.75
AtrioventricularNode4.5
BDCA4+_DentriticCells6.15
Bonemarrow5.55
BronchialEpithelialCells5.4
CD105+_Endothelial5.6
CD14+_Monocytes6.1
CD19+_BCells(neg._sel.)5.8
CD33+_Myeloid7
CD34+7.05
CD4+_Tcells6
CD56+_NKCells6.35
CD71+_EarlyErythroid5.2
CD8+_Tcells5.25
CardiacMyocytes7.9
Caudatenucleus5.15
Cerebellum4.6
CerebellumPeduncles6.4
CiliaryGanglion4.15
CingulateCortex5.9
Colorectaladenocarcinoma5.7
DorsalRootGanglion4.5
FetalThyroid17.85
Fetalbrain5.65
Fetalliver4.85
Fetallung4.85
GlobusPallidus4.2
Heart7.9
Hypothalamus6.2
Kidney4.5
Leukemia_chronicMyelogenousK-5625.15
Leukemia_promyelocytic-HL-605
Leukemialymphoblastic(MOLT-4)4.45
Liver7.55
Lung6.4
Lymphnode4.75
Lymphoma_burkitts(Daudi)7.2
Lymphoma_burkitts(Raji)8.3
MedullaOblongata5.1
OccipitalLobe5.1
OlfactoryBulb4.4
Ovary3.95
Pancreas8.75
PancreaticIslet6.8
ParietalLobe6
Pituitary6.7
Placenta5.7
Pons5.4
PrefrontalCortex7.1
Prostate58.6
Salivarygland4.65
SkeletalMuscle7.05
Skin4.6
SmoothMuscle6.45
Spinalcord6
SubthalamicNucleus5.25
SuperiorCervicalGanglion6.35
TemporalLobe5.15
Testis4.95
TestisGermCell4.7
TestisIntersitial4.7
TestisLeydigCell5.6
TestisSeminiferousTubule4.85
Thalamus5.8
Thymus4.5
Thyroid9.1
Tongue5.65
Tonsil5.55
Trachea4.85
TrigeminalGanglion5.7
Uterus4.55
UterusCorpus5
WholeBlood6.1
Wholebrain5
colon5.75
pineal_day11.72
pineal_night13.42
retina8.5
small_intestine5.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5923_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.23 ± 0.29
Basal Forebrain5.65 ± 0.69
Basal Part of Pons6.15 ± 0.32
Cerebellar Cortex5.44 ± 0.46
Cerebellar Nuclei5.78 ± 0.24
Claustrum6.7 ± 0.54
Epithalamus5.23 ± 0.41
Frontal Lobe5.87 ± 0.55
Globus Pallidus5.29 ± 0.62
Hypothalamus6.06 ± 0.67
Insula5.94 ± 0.38
Limbic Lobe6.29 ± 0.38
Mesencephalon6 ± 0.6
Myelencephalon5.82 ± 0.59
Occipital Lobe5.64 ± 0.57
Parietal Lobe5.9 ± 0.6
Pontine Tegmentum5.75 ± 0.48
Striatum5.75 ± 0.54
Subthalamus5.07 ± 0.41
Temporal Lobe6 ± 0.42
Thalamus5.41 ± 0.45
White Matter5.9 ± 0.57
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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