AutismKB 2.0

Annotation Detail for LMO2


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Basic Information Top
Gene Symbol:LMO2 ( RBTN2,RBTNL1,RHOM2,TTG2 )
Gene Full Name: LIM domain only 2 (rhombotin-like 1)
Band: 11p13
Quick LinksEntrez ID:4005; OMIM: 180385; Uniprot ID:RBTN2_HUMAN; ENSEMBL ID: ENSG00000135363; HGNC ID: 6642
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus31 / 56401254
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma13 / 106883121
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal96 / 336030728
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow2 / 4880140
brain23 / 110098920
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye7 / 21105433
heart1 / 8962611
intestine1 / 2344724
kidney6 / 21177728
larynx0 / 241450 
liver4 / 20774319
lung15 / 33697444
lymph0 / 442700 
lymph node9 / 9161098
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas8 / 21481237
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta10 / 28082535
prostate5 / 18934526
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204249_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.85
Adipocyte14.7
AdrenalCortex27.8
Adrenalgland40.7
Amygdala206.65
Appendix36.2
AtrioventricularNode21.55
BDCA4+_DentriticCells426.15
Bonemarrow236
BronchialEpithelialCells13.4
CD105+_Endothelial3107.6
CD14+_Monocytes1610.7
CD19+_BCells(neg._sel.)122.9
CD33+_Myeloid1996.95
CD34+3010.1
CD4+_Tcells18.3
CD56+_NKCells235.55
CD71+_EarlyErythroid1286.35
CD8+_Tcells13.2
CardiacMyocytes154.75
Caudatenucleus81.65
Cerebellum51.75
CerebellumPeduncles52.95
CiliaryGanglion35.85
CingulateCortex26.9
Colorectaladenocarcinoma196.3
DorsalRootGanglion10.6
FetalThyroid46.95
Fetalbrain52
Fetalliver505.75
Fetallung201.85
GlobusPallidus27.25
Heart39
Hypothalamus133.95
Kidney63
Leukemia_chronicMyelogenousK-56295.6
Leukemia_promyelocytic-HL-6010.2
Leukemialymphoblastic(MOLT-4)31.3
Liver41.4
Lung355.35
Lymphnode77.15
Lymphoma_burkitts(Daudi)15.2
Lymphoma_burkitts(Raji)88.25
MedullaOblongata32.55
OccipitalLobe52.4
OlfactoryBulb47.6
Ovary28.55
Pancreas14.05
PancreaticIslet106
ParietalLobe34.6
Pituitary51.05
Placenta327.25
Pons43.25
PrefrontalCortex122.55
Prostate49.75
Salivarygland27.35
SkeletalMuscle25.1
Skin18.7
SmoothMuscle40.8
Spinalcord124.9
SubthalamicNucleus34.4
SuperiorCervicalGanglion30.9
TemporalLobe32.9
Testis30.05
TestisGermCell29
TestisIntersitial18.05
TestisLeydigCell15.05
TestisSeminiferousTubule10.05
Thalamus76.9
Thymus33.2
Thyroid249.45
Tongue33.75
Tonsil125.45
Trachea75.65
TrigeminalGanglion25.7
Uterus124.3
UterusCorpus26.05
WholeBlood739.95
Wholebrain121.6
colon40.05
pineal_day62.62
pineal_night55.04
retina367.425
small_intestine78.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_17073_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.92 ± 1.09
Basal Forebrain2.65 ± 0.59
Basal Part of Pons2 ± 0.44
Cerebellar Cortex2.31 ± 0.73
Cerebellar Nuclei2.71 ± 0.72
Claustrum3.37 ± 0.95
Epithalamus4.31 ± 1.06
Frontal Lobe2.35 ± 0.87
Globus Pallidus3.04 ± 0.71
Hypothalamus2.43 ± 0.67
Insula2.69 ± 0.86
Limbic Lobe2.5 ± 0.83
Mesencephalon2.54 ± 0.75
Myelencephalon2.57 ± 0.82
Occipital Lobe2.65 ± 0.93
Parietal Lobe2.6 ± 0.9
Pontine Tegmentum2.72 ± 0.9
Striatum2.88 ± 0.83
Subthalamus2.6 ± 0.26
Temporal Lobe2.47 ± 0.79
Thalamus2.4 ± 0.61
White Matter2.68 ± 0.49
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lmo2CBCerebellum27.86
25.95
Lmo2CTXCerebral cortex4.11
2.78
Lmo2HIPHippocampal region8.07
3.75
Lmo2HPFHippocampal formation7.67
3.98
Lmo2HYHypothalamus6.38
4.16
Lmo2LSXLateral septal complex4.83
3.82
Lmo2MBMidbrain3.84
3.54
Lmo2MYMedulla11.88
8.31
Lmo2OLFOlfactory bulb17.83
10.24
Lmo2PPons8.27
6.88
Lmo2PALPallidum9.7
5.63
Lmo2RHPRetrohippocampal region6.15
3.75
Lmo2sAMYStriatum-like amygdalar nuclei7.17
4.97
Lmo2STRStriatum32
15.3
Lmo2STRdStriatum dorsal region41.01
19.61
Lmo2STRvStriatum ventral region38.92
16.43
Lmo2THThalamus3.91
2.37
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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