Annotation Detail for LOXL2
Basic Information Top
| Gene Symbol: | LOXL2 ( LOR2,WS9-14 ) |
|---|---|
| Gene Full Name: | lysyl oxidase-like 2 |
| Band: | 8p21.3 |
| Quick Links | Entrez ID:4017; OMIM: 606663; Uniprot ID:LOXL2_HUMAN; ENSEMBL ID: ENSG00000134013; HGNC ID: 6666 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.626637
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 60 / 70761 | 847 |  |
| blastocyst | 14 / 62319 | 224 | |
| fetus | 48 / 564012 | 85 |  |
| neonate | 2 / 31097 | 64 | |
| infant | 1 / 23620 | 42 |  |
| juvenile | 3 / 55556 | 53 | |
| adult | 168 / 1939121 | 86 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 6 / 94178 | 63 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 41 / 82823 | 495 | |
| colorectal tumor | 4 / 114246 | 35 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 43 / 263845 | 162 | |
| glioma | 9 / 106883 | 84 | |
| head and neck tumor | 11 / 136302 | 80 | |
| kidney tumor | 10 / 68959 | 145 | |
| leukemia | 1 / 95842 | 10 |  |
| liver tumor | 10 / 96359 | 103 | |
| lung tumor | 5 / 103127 | 48 | |
| lymphoma | 17 / 71755 | 236 | |
| non-neoplasia | 13 / 97250 | 133 | |
| normal | 356 / 3360307 | 105 | |
| ovarian tumor | 5 / 76682 | 65 | |
| pancreatic tumor | 12 / 104616 | 114 | |
| primitive neuroectodermal tumor of the CNS | 12 / 125680 | 95 | |
| prostate cancer | 12 / 102680 | 116 | |
| retinoblastoma | 7 / 46356 | 151 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 6 / 125191 | 47 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 2 / 13106 | 152 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 20 / 71655 | 279 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 42 / 1100989 | 38 | |
| cervix | 10 / 48171 | 207 | |
| connective tissue | 28 / 149255 | 187 | |
| ear | 1 / 16212 | 61 | |
| embryonic tissue | 77 / 215722 | 356 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 18 / 211054 | 85 | |
| heart | 9 / 89626 | 100 | |
| intestine | 20 / 234472 | 85 | |
| kidney | 36 / 211777 | 169 | |
| larynx | 0 / 24145 | 0 | |
| liver | 10 / 207743 | 48 | |
| lung | 59 / 336974 | 175 | |
| lymph | 8 / 44270 | 180 | |
| lymph node | 11 / 91610 | 120 | |
| mammary gland | 8 / 153271 | 52 | |
| mouth | 5 / 67052 | 74 | |
| muscle | 27 / 107715 | 250 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 14 / 102051 | 137 | |
| pancreas | 12 / 214812 | 55 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 31 / 280825 | 110 | |
| prostate | 12 / 189345 | 63 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 31 / 210574 | 147 | |
| spleen | 2 / 53952 | 37 | |
| stomach | 4 / 96619 | 41 | |
| testis | 27 / 330442 | 81 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 8 / 47473 | 168 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 2 / 13680 | 146 | |
| uterus | 14 / 232878 | 60 | |
| vascular | 11 / 51780 | 212 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 202998_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 4.9 | |
| Adipocyte | 19.8 | |
| AdrenalCortex | 4.3 | |
| Adrenalgland | 3.45 | |
| Amygdala | 4.1 | |
| Appendix | 4.5 | |
| AtrioventricularNode | 3.4 | |
| BDCA4+_DentriticCells | 4.35 | |
| Bonemarrow | 4.05 | |
| BronchialEpithelialCells | 20.8 | |
| CD105+_Endothelial | 4.15 | |
| CD14+_Monocytes | 4.2 | |
| CD19+_BCells(neg._sel.) | 4.25 | |
| CD33+_Myeloid | 5.2 | |
| CD34+ | 5.05 | |
| CD4+_Tcells | 4.4 | |
| CD56+_NKCells | 4.7 | |
| CD71+_EarlyErythroid | 3.8 | |
| CD8+_Tcells | 3.9 | |
| CardiacMyocytes | 978.5 | |
| Caudatenucleus | 3.6 | |
| Cerebellum | 3.25 | |
| CerebellumPeduncles | 4.6 | |
| CiliaryGanglion | 3.65 | |
| CingulateCortex | 4.1 | |
| Colorectaladenocarcinoma | 4.5 | |
| DorsalRootGanglion | 3.5 | |
| FetalThyroid | 4.1 | |
| Fetalbrain | 4.05 | |
| Fetalliver | 3.45 | |
| Fetallung | 12.3 | |
| GlobusPallidus | 3.1 | |
| Heart | 5.25 | |
| Hypothalamus | 4.45 | |
| Kidney | 3.3 | |
| Leukemia_chronicMyelogenousK-562 | 3.6 | |
| Leukemia_promyelocytic-HL-60 | 6.95 | |
| Leukemialymphoblastic(MOLT-4) | 3.3 | |
| Liver | 5.45 | |
| Lung | 4.55 | |
| Lymphnode | 3.5 | |
| Lymphoma_burkitts(Daudi) | 5.15 | |
| Lymphoma_burkitts(Raji) | 6 | |
| MedullaOblongata | 3.7 | |
| OccipitalLobe | 3.5 | |
| OlfactoryBulb | 3.65 | |
| Ovary | 2.75 | |
| Pancreas | 3.3 | |
| PancreaticIslet | 4.35 | |
| ParietalLobe | 4.3 | |
| Pituitary | 4.75 | |
| Placenta | 84.95 | |
| Pons | 3.9 | |
| PrefrontalCortex | 5 | |
| Prostate | 4.8 | |
| Salivarygland | 3.2 | |
| SkeletalMuscle | 4.95 | |
| Skin | 3.4 | |
| SmoothMuscle | 1998.6 |  |
| Spinalcord | 4.35 | |
| SubthalamicNucleus | 3.7 | |
| SuperiorCervicalGanglion | 5.05 | |
| TemporalLobe | 3.6 | |
| Testis | 3.5 | |
| TestisGermCell | 3.4 | |
| TestisIntersitial | 3.4 | |
| TestisLeydigCell | 4 | |
| TestisSeminiferousTubule | 3.5 | |
| Thalamus | 4.1 | |
| Thymus | 3.2 | |
| Thyroid | 5.05 | |
| Tongue | 4.35 | |
| Tonsil | 3.95 | |
| Trachea | 3.4 | |
| TrigeminalGanglion | 4.75 | |
| Uterus | 5.1 | |
| UterusCorpus | 13.35 | |
| WholeBlood | 4.35 | |
| Wholebrain | 3.35 | |
| colon | 4.05 | |
| pineal_day | 5.02 | |
| pineal_night | 5.84 | |
| retina | 4.9 | |
| small_intestine | 49.55 | |
- Probe name: CUST_14399_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.03 ± 1.07 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.58 ± 0.34 | |
| Basal Part of Pons | 2.84 ± 0.47 | |
| Cerebellar Cortex | 2.45 ± 0.43 | |
| Cerebellar Nuclei | 2.16 ± 0.62 | |
| Claustrum | 2.5 ± 0.87 | |
| Epithalamus | 1.44 ± 0.81 | |
| Frontal Lobe | 1.53 ± 0.74 | |
| Globus Pallidus | 2.09 ± 0.81 | |
| Hypothalamus | 1.82 ± 0.75 | |
| Insula | 1.33 ± 0.42 | |
| Limbic Lobe | 1.6 ± 0.78 | |
| Mesencephalon | 1.73 ± 0.86 | |
| Myelencephalon | 1.81 ± 0.79 | |
| Occipital Lobe | 2.33 ± 0.95 | |
| Parietal Lobe | 1.62 ± 0.77 | |
| Pontine Tegmentum | 1.61 ± 0.68 | |
| Striatum | 1.91 ± 0.93 | |
| Subthalamus | 1.79 ± 0.63 | |
| Temporal Lobe | 1.56 ± 0.71 | |
| Thalamus | 1.82 ± 0.69 | |
| White Matter | 3.58 ± 0.66 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Loxl2 | CB | Cerebellum | 21.57 | |
| 33.25 | | |||
| Loxl2 | CTX | Cerebral cortex | 3.55 | |
| 2.91 | | |||
| Loxl2 | HIP | Hippocampal region | 1.33 | |
| 1.26 | | |||
| Loxl2 | HPF | Hippocampal formation | 7.18 | |
| 6.69 | | |||
| Loxl2 | HY | Hypothalamus | 1.29 | |
| 1.24 | | |||
| Loxl2 | LSX | Lateral septal complex | 0.32 | |
| 0.7 | | |||
| Loxl2 | MB | Midbrain | 11.65 | |
| 12.81 | | |||
| Loxl2 | MY | Medulla | 37.55 | |
| 54.83 | | |||
| Loxl2 | OLF | Olfactory bulb | 3.51 | |
| 2.7 | | |||
| Loxl2 | P | Pons | 31.41 | |
| 38.44 | | |||
| Loxl2 | PAL | Pallidum | 6.18 | |
| 7.3 | | |||
| Loxl2 | RHP | Retrohippocampal region | 13.98 | |
| 11.69 | | |||
| Loxl2 | sAMY | Striatum-like amygdalar nuclei | 3.96 | |
| 4.05 | | |||
| Loxl2 | STR | Striatum | 2.24 | |
| 1.94 | | |||
| Loxl2 | STRd | Striatum dorsal region | 1.89 | |
| 1.57 | | |||
| Loxl2 | STRv | Striatum ventral region | 2.79 | |
| 2.14 | | |||
| Loxl2 | TH | Thalamus | 4.46 | |
| 4.91 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00361309 | 7 | 538 | 544 | GAGVACS | Peptide Atlas |