Annotation Detail for LRP6
Basic Information Top
| Gene Symbol: | LRP6 ( ADCAD2,FLJ90062,FLJ90421 ) |
|---|---|
| Gene Full Name: | low density lipoprotein receptor-related protein 6 |
| Band: | 12p13.2 |
| Quick Links | Entrez ID:4040; OMIM: 603507; Uniprot ID:LRP6_HUMAN; ENSEMBL ID: ENSG00000070018; HGNC ID: 6698 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.658913
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 3 / 62319 | 48 | |
| fetus | 25 / 564012 | 44 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 74 / 1939121 | 38 | |
| embryoid body | 2 / 70761 | 28 | |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 7 / 564012 | 12 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 23 / 1939121 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 2 / 34366 | 58 |  |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 9 / 114246 | 78 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 17 / 263845 | 64 | |
| glioma | 1 / 106883 | 9 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 3 / 96359 | 31 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 97 / 3360307 | 28 | |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 4 / 90257 | 44 | |
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 1 / 114246 | 8 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 1 / 263845 | 3 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 40 / 3360307 | 11 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 1 / 123478 | 8 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 21 / 1100989 | 19 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 3 / 16212 | 185 | |
| embryonic tissue | 8 / 215722 | 37 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 6 / 211054 | 28 | |
| heart | 7 / 89626 | 78 | |
| intestine | 13 / 234472 | 55 | |
| kidney | 11 / 211777 | 51 | |
| larynx | 0 / 24145 | 0 | |
| liver | 7 / 207743 | 33 | |
| lung | 7 / 336974 | 20 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 4 / 153271 | 26 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 2 / 214812 | 9 | |
| parathyroid | 4 / 20539 | 194 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 13 / 280825 | 46 | |
| prostate | 6 / 189345 | 31 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 3 / 210574 | 14 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 2 / 96619 | 20 | |
| testis | 8 / 330442 | 24 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 5 / 52413 | 95 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 9 / 232878 | 38 | |
| vascular | 0 / 51780 | 0 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 2 / 33197 | 60 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 11 / 1100989 | 9 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 4 / 215722 | 18 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 2 / 211054 | 9 | |
| heart | 3 / 89626 | 33 | |
| intestine | 1 / 234472 | 4 | |
| kidney | 2 / 211777 | 9 | |
| larynx | 0 / 24145 | 0 | |
| liver | 6 / 207743 | 28 | |
| lung | 1 / 336974 | 2 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 2 / 280825 | 7 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 2 / 210574 | 9 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 1 / 330442 | 3 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 5 / 232878 | 21 | |
| vascular | 3 / 51780 | 57 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 34697_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 16.2 | |
| Adipocyte | 21.15 | |
| AdrenalCortex | 48.15 | |
| Adrenalgland | 24.2 | |
| Amygdala | 19.1 | |
| Appendix | 54.1 | |
| AtrioventricularNode | 29.95 | |
| BDCA4+_DentriticCells | 15.25 | |
| Bonemarrow | 27.45 | |
| BronchialEpithelialCells | 18.2 | |
| CD105+_Endothelial | 20.75 | |
| CD14+_Monocytes | 17.9 | |
| CD19+_BCells(neg._sel.) | 16.4 | |
| CD33+_Myeloid | 22.35 | |
| CD34+ | 20.7 | |
| CD4+_Tcells | 16.15 | |
| CD56+_NKCells | 15.75 | |
| CD71+_EarlyErythroid | 19 | |
| CD8+_Tcells | 14.1 | |
| CardiacMyocytes | 43.5 | |
| Caudatenucleus | 20.9 | |
| Cerebellum | 18.6 | |
| CerebellumPeduncles | 39.4 | |
| CiliaryGanglion | 24.3 | |
| CingulateCortex | 30.3 | |
| Colorectaladenocarcinoma | 22.65 | |
| DorsalRootGanglion | 33.3 | |
| FetalThyroid | 43.6 | |
| Fetalbrain | 24 | |
| Fetalliver | 26.25 | |
| Fetallung | 16.45 | |
| GlobusPallidus | 19.15 | |
| Heart | 40.05 | |
| Hypothalamus | 22.9 | |
| Kidney | 24.75 | |
| Leukemia_chronicMyelogenousK-562 | 20.35 | |
| Leukemia_promyelocytic-HL-60 | 18.55 | |
| Leukemialymphoblastic(MOLT-4) | 15.9 | |
| Liver | 47.95 | |
| Lung | 23.55 | |
| Lymphnode | 15.95 | |
| Lymphoma_burkitts(Daudi) | 30.05 | |
| Lymphoma_burkitts(Raji) | 38.45 | |
| MedullaOblongata | 32.85 | |
| OccipitalLobe | 21.6 | |
| OlfactoryBulb | 18.5 | |
| Ovary | 21.25 | |
| Pancreas | 23 | |
| PancreaticIslet | 27.55 | |
| ParietalLobe | 32.05 | |
| Pituitary | 31.65 | |
| Placenta | 20.85 | |
| Pons | 28.5 | |
| PrefrontalCortex | 28.65 | |
| Prostate | 23.15 | |
| Salivarygland | 20.05 | |
| SkeletalMuscle | 49.5 | |
| Skin | 39.25 | |
| SmoothMuscle | 23.35 | |
| Spinalcord | 22.7 | |
| SubthalamicNucleus | 25.9 | |
| SuperiorCervicalGanglion | 67.85 | |
| TemporalLobe | 25.55 | |
| Testis | 21.25 | |
| TestisGermCell | 25.25 | |
| TestisIntersitial | 23.45 | |
| TestisLeydigCell | 28.1 | |
| TestisSeminiferousTubule | 22.2 | |
| Thalamus | 27.45 | |
| Thymus | 16.1 | |
| Thyroid | 22.75 | |
| Tongue | 39 | |
| Tonsil | 25.2 | |
| Trachea | 21.1 | |
| TrigeminalGanglion | 44.95 | |
| Uterus | 19.35 | |
| UterusCorpus | 38.5 | |
| WholeBlood | 21.55 | |
| Wholebrain | 14.5 | |
| colon | 25.65 | |
| pineal_day | 23.78 | |
| pineal_night | 24.12 | |
| retina | 25.725 | |
| small_intestine | 19.25 | |
- Probe name: A_23_P150827
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 8.54 ± 0.25 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 8.62 ± 0.26 | |
| Basal Part of Pons | 8.07 ± 0.22 | |
| Cerebellar Cortex | 8.49 ± 0.21 | |
| Cerebellar Nuclei | 8.39 ± 0.19 | |
| Claustrum | 8.64 ± 0.25 | |
| Epithalamus | 9.1 ± 0.38 | |
| Frontal Lobe | 8.43 ± 0.29 | |
| Globus Pallidus | 9.1 ± 0.31 | |
| Hypothalamus | 8.55 ± 0.28 | |
| Insula | 8.46 ± 0.27 | |
| Limbic Lobe | 8.42 ± 0.37 | |
| Mesencephalon | 8.65 ± 0.31 | |
| Myelencephalon | 8.54 ± 0.37 | |
| Occipital Lobe | 8.69 ± 0.27 | |
| Parietal Lobe | 8.48 ± 0.23 | |
| Pontine Tegmentum | 8.59 ± 0.24 | |
| Striatum | 8.94 ± 0.38 | |
| Subthalamus | 8.41 ± 0.31 | |
| Temporal Lobe | 8.38 ± 0.25 | |
| Thalamus | 8.54 ± 0.21 | |
| White Matter | 9.31 ± 0.12 | |
Mouse Brain ISH 