AutismKB 2.0

Annotation Detail for LSAMP


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Basic Information Top
Gene Symbol:LSAMP ( FLJ34254,FLJ35396,FLJ37216,FLJ54658,IGLON3,LAMP )
Gene Full Name: limbic system-associated membrane protein
Band: 3q13.31
Quick LinksEntrez ID:4045; OMIM: 603241; Uniprot ID:LSAMP_HUMAN; ENSEMBL ID: ENSG00000185565; HGNC ID: 6705
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus24 / 56401242
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult56 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma8 / 10688374
head and neck tumor4 / 13630229
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal145 / 336030743
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor6 / 12494948
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain63 / 110098957
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye17 / 21105480
heart1 / 8962611
intestine3 / 23447212
kidney5 / 21177723
larynx0 / 241450 
liver1 / 2077434
lung11 / 33697432
lymph0 / 442700 
lymph node7 / 9161076
mammary gland0 / 1532710 
mouth2 / 6705229
muscle4 / 10771537
nerve1 / 1576863
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate4 / 18934521
salivary gland2 / 2015599
skin7 / 21057433
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214460_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.35
Adipocyte4.65
AdrenalCortex5.15
Adrenalgland3.95
Amygdala5
Appendix4.75
AtrioventricularNode3.65
BDCA4+_DentriticCells4.9
Bonemarrow4.8
BronchialEpithelialCells4.55
CD105+_Endothelial4.6
CD14+_Monocytes4.9
CD19+_BCells(neg._sel.)4.9
CD33+_Myeloid5.7
CD34+5.9
CD4+_Tcells4.8
CD56+_NKCells5.35
CD71+_EarlyErythroid4.35
CD8+_Tcells4.3
CardiacMyocytes5.8
Caudatenucleus4.2
Cerebellum3.8
CerebellumPeduncles5.35
CiliaryGanglion3.4
CingulateCortex5.9
Colorectaladenocarcinoma4.65
DorsalRootGanglion3.55
FetalThyroid4.5
Fetalbrain4.6
Fetalliver4.05
Fetallung3.75
GlobusPallidus3.4
Heart6.1
Hypothalamus5.1
Kidney3.9
Leukemia_chronicMyelogenousK-5624.2
Leukemia_promyelocytic-HL-604.15
Leukemialymphoblastic(MOLT-4)3.7
Liver6.2
Lung5
Lymphnode4
Lymphoma_burkitts(Daudi)6.05
Lymphoma_burkitts(Raji)6.8
MedullaOblongata4.3
OccipitalLobe4.2
OlfactoryBulb3.7
Ovary3.1
Pancreas3.75
PancreaticIslet5
ParietalLobe5.05
Pituitary5.45
Placenta4.65
Pons4.45
PrefrontalCortex5.7
Prostate5.55
Salivarygland3.75
SkeletalMuscle5.65
Skin3.7
SmoothMuscle5.25
Spinalcord5
SubthalamicNucleus4.3
SuperiorCervicalGanglion5.2
TemporalLobe4.35
Testis4
TestisGermCell3.8
TestisIntersitial3.9
TestisLeydigCell4.6
TestisSeminiferousTubule4.05
Thalamus4.75
Thymus3.6
Thyroid5.75
Tongue4.65
Tonsil4.55
Trachea3.9
TrigeminalGanglion4.85
Uterus3.75
UterusCorpus4.2
WholeBlood5.05
Wholebrain3.95
colon4.65
pineal_day17.94
pineal_night17.1
retina5.825
small_intestine4.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10128_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.92 ± 0.23
Basal Forebrain8.5 ± 0.15
Basal Part of Pons9.06 ± 0.16
Cerebellar Cortex8.7 ± 0.25
Cerebellar Nuclei8.31 ± 0.34
Claustrum8.98 ± 0.35
Epithalamus8.35 ± 0.47
Frontal Lobe8.89 ± 0.33
Globus Pallidus8.94 ± 0.25
Hypothalamus8.72 ± 0.18
Insula8.8 ± 0.33
Limbic Lobe8.93 ± 0.34
Mesencephalon8.63 ± 0.31
Myelencephalon8.71 ± 0.34
Occipital Lobe8.49 ± 0.25
Parietal Lobe8.72 ± 0.29
Pontine Tegmentum8.76 ± 0.25
Striatum8.73 ± 0.33
Subthalamus8.57 ± 0.15
Temporal Lobe8.74 ± 0.28
Thalamus8.8 ± 0.38
White Matter7.63 ± 0.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
LsampCBCerebellum16.01
18.72
LsampCTXCerebral cortex7.94
7.46
LsampHIPHippocampal region33.08
33.54
LsampHPFHippocampal formation24.18
22.94
LsampHYHypothalamus10.35
8.92
LsampLSXLateral septal complex5
3.78
LsampMBMidbrain9
9.83
LsampMYMedulla10.19
11.82
LsampOLFOlfactory bulb14.16
13.07
LsampPPons11.76
13.17
LsampPALPallidum4.51
4.51
LsampRHPRetrohippocampal region9.19
8.18
LsampsAMYStriatum-like amygdalar nuclei11.61
10.06
LsampSTRStriatum2.21
1.92
LsampSTRdStriatum dorsal region0.51
0.48
LsampSTRvStriatum ventral region1.59
1.42
LsampTHThalamus7.89
7.7
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00040043 16 174 189 EFEGEEEYLEILGITR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018