AutismKB 2.0

Annotation Detail for LSP1


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Basic Information Top
Gene Symbol:LSP1 ( WP34,pp52 )
Gene Full Name: lymphocyte-specific protein 1
Band: 11p15.5
Quick LinksEntrez ID:4046; OMIM: 153432; Uniprot ID:LSP1_HUMAN; ENSEMBL ID: ENSG00000130592; HGNC ID: 6707
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus23 / 56401240
neonate5 / 31097160
infant0 / 236200 
juvenile1 / 5555617
adult167 / 193912186
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor6 / 12794468
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor1 / 2638453
glioma7 / 10688365
head and neck tumor6 / 13630244
kidney tumor1 / 6895914
leukemia28 / 95842292
liver tumor4 / 9635941
lung tumor6 / 10312758
lymphoma35 / 71755487
non-neoplasia11 / 97250113
normal288 / 336030785
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland18 / 33197542
ascites0 / 400150 
bladder0 / 297570 
blood40 / 123478323
bone10 / 71655139
bone marrow9 / 48801184
brain20 / 110098918
cervix3 / 4817162
connective tissue11 / 14925573
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus2 / 2020998
eye8 / 21105437
heart7 / 8962678
intestine17 / 23447272
kidney4 / 21177718
larynx1 / 2414541
liver7 / 20774333
lung19 / 33697456
lymph29 / 44270655
lymph node16 / 91610174
mammary gland8 / 15327152
mouth3 / 6705244
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta30 / 280825106
prostate5 / 18934526
salivary gland3 / 20155148
skin2 / 2105749
spleen21 / 53952389
stomach5 / 9661951
testis7 / 33044221
thymus7 / 8113186
thyroid3 / 4747363
tonsil15 / 16999882
trachea2 / 5241338
umbilical cord3 / 13680219
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203523_at
Cell line Expression level Expression bar
721_B_lymphoblasts646.7
Adipocyte52.8
AdrenalCortex105.35
Adrenalgland82.6
Amygdala32.4
Appendix43.55
AtrioventricularNode26.6
BDCA4+_DentriticCells820.45
Bonemarrow156.35
BronchialEpithelialCells17.2
CD105+_Endothelial14.75
CD14+_Monocytes1596.3
CD19+_BCells(neg._sel.)669.3
CD33+_Myeloid1045.05
CD34+82.25
CD4+_Tcells244.3
CD56+_NKCells1075.9
CD71+_EarlyErythroid37.15
CD8+_Tcells396.2
CardiacMyocytes47.8
Caudatenucleus30.2
Cerebellum24.55
CerebellumPeduncles42.05
CiliaryGanglion28.45
CingulateCortex47.9
Colorectaladenocarcinoma18.05
DorsalRootGanglion26.8
FetalThyroid41.3
Fetalbrain36.75
Fetalliver25.8
Fetallung36.9
GlobusPallidus23.4
Heart145.1
Hypothalamus20.5
Kidney25.6
Leukemia_chronicMyelogenousK-56219.5
Leukemia_promyelocytic-HL-6084.95
Leukemialymphoblastic(MOLT-4)50.65
Liver58.5
Lung118.6
Lymphnode125.25
Lymphoma_burkitts(Daudi)290.6
Lymphoma_burkitts(Raji)569
MedullaOblongata29.4
OccipitalLobe30.75
OlfactoryBulb34.9
Ovary17.55
Pancreas20.1
PancreaticIslet38.55
ParietalLobe37.35
Pituitary45.75
Placenta39.5
Pons50.75
PrefrontalCortex22.8
Prostate41.9
Salivarygland48.4
SkeletalMuscle53.35
Skin34.6
SmoothMuscle24
Spinalcord38.2
SubthalamicNucleus21.4
SuperiorCervicalGanglion41.85
TemporalLobe51.35
Testis32.45
TestisGermCell30.4
TestisIntersitial40.7
TestisLeydigCell38.55
TestisSeminiferousTubule21.35
Thalamus29.2
Thymus66.15
Thyroid47.25
Tongue57.15
Tonsil160.7
Trachea56.45
TrigeminalGanglion43.8
Uterus80.1
UterusCorpus36.6
WholeBlood2207.75
Wholebrain14.95
colon31.85
pineal_day18.52
pineal_night16
retina96.725
small_intestine25.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_613_PI417507815
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.83 ± 0.28
Basal Forebrain8.6 ± 0.15
Basal Part of Pons9 ± 0.25
Cerebellar Cortex8.49 ± 0.19
Cerebellar Nuclei8.6 ± 0.16
Claustrum8.52 ± 0.29
Epithalamus8.74 ± 0.35
Frontal Lobe8.79 ± 0.32
Globus Pallidus8.58 ± 0.54
Hypothalamus8.66 ± 0.19
Insula8.83 ± 0.28
Limbic Lobe8.93 ± 0.29
Mesencephalon8.66 ± 0.32
Myelencephalon8.65 ± 0.35
Occipital Lobe8.41 ± 0.26
Parietal Lobe8.69 ± 0.32
Pontine Tegmentum8.6 ± 0.27
Striatum8.76 ± 0.3
Subthalamus8.41 ± 0.12
Temporal Lobe8.85 ± 0.33
Thalamus8.33 ± 0.3
White Matter8.39 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lsp1CBCerebellum56.05
32.49
Lsp1CTXCerebral cortex56.48
29.28
Lsp1HIPHippocampal region43.73
23.72
Lsp1HPFHippocampal formation42.58
24.98
Lsp1HYHypothalamus26.82
11.65
Lsp1LSXLateral septal complex13.03
6.74
Lsp1MBMidbrain29.07
17.08
Lsp1MYMedulla56.83
33.78
Lsp1OLFOlfactory bulb57.49
27.36
Lsp1PPons40.63
23.97
Lsp1PALPallidum22.66
11.06
Lsp1RHPRetrohippocampal region41.36
25.82
Lsp1sAMYStriatum-like amygdalar nuclei15.89
7.34
Lsp1STRStriatum16.53
6.81
Lsp1STRdStriatum dorsal region13.96
5.9
Lsp1STRvStriatum ventral region25.27
8.51
Lsp1THThalamus44.91
22.05
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
LSP1_HUMAN_40 20 40 59 DRQLQAQDEEGGGHVPERPK PRIDE
LSP1_HUMAN_42 18 42 59 QLQAQDEEGGGHVPERPK PRIDE
PAp00001960 15 128 142 EDSDEVHLEELSLSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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