AutismKB 2.0

Annotation Detail for FAM45A


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Basic Information Top
Gene Symbol:FAM45A ( - )
Gene Full Name: family with sequence similarity 45, member A
Band: 10q26.11
Quick LinksEntrez ID:404636; OMIM: NA; Uniprot ID:FA45A_HUMAN; ENSEMBL ID: ENSG00000119979; HGNC ID: 31793
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus5 / 5640128
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult9 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal29 / 33603078
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain4 / 11009893
cervix0 / 481710 
connective tissue0 / 1492550 
ear1 / 1621261
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine1 / 2344724
kidney3 / 21177714
larynx0 / 241450 
liver1 / 2077434
lung6 / 33697417
lymph0 / 442700 
lymph node3 / 9161032
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate4 / 18934521
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221804_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts38.7
Adipocyte79.95
AdrenalCortex10.5
Adrenalgland19.15
Amygdala136.5
Appendix5.35
AtrioventricularNode4.95
BDCA4+_DentriticCells89
Bonemarrow47.6
BronchialEpithelialCells180.75
CD105+_Endothelial434.9
CD14+_Monocytes449.7
CD19+_BCells(neg._sel.)17.85
CD33+_Myeloid515.15
CD34+453.1
CD4+_Tcells72
CD56+_NKCells94.05
CD71+_EarlyErythroid21.85
CD8+_Tcells77.85
CardiacMyocytes36.35
Caudatenucleus42.8
Cerebellum9.2
CerebellumPeduncles10.5
CiliaryGanglion4.45
CingulateCortex36.4
Colorectaladenocarcinoma49.25
DorsalRootGanglion10.85
FetalThyroid48.65
Fetalbrain121.2
Fetalliver53.35
Fetallung22.7
GlobusPallidus32.9
Heart8.25
Hypothalamus61.3
Kidney28.8
Leukemia_chronicMyelogenousK-56210.3
Leukemia_promyelocytic-HL-6059.2
Leukemialymphoblastic(MOLT-4)38.5
Liver10.4
Lung14.4
Lymphnode28.05
Lymphoma_burkitts(Daudi)23.25
Lymphoma_burkitts(Raji)48.95
MedullaOblongata37.75
OccipitalLobe53.45
OlfactoryBulb18.45
Ovary6.85
Pancreas7.9
PancreaticIslet11.15
ParietalLobe33.05
Pituitary48.45
Placenta62.8
Pons11.1
PrefrontalCortex97.25
Prostate93.5
Salivarygland18.05
SkeletalMuscle9.1
Skin6.55
SmoothMuscle175.7
Spinalcord68.45
SubthalamicNucleus36.65
SuperiorCervicalGanglion8.8
TemporalLobe41.85
Testis6.85
TestisGermCell6.85
TestisIntersitial6.55
TestisLeydigCell7.55
TestisSeminiferousTubule6.55
Thalamus49.35
Thymus17.85
Thyroid69.45
Tongue9.9
Tonsil26.25
Trachea19.6
TrigeminalGanglion8.4
Uterus35.5
UterusCorpus5.7
WholeBlood279.5
Wholebrain43.7
colon47.7
pineal_day57.94
pineal_night56.88
retina38.9
small_intestine34.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P138004
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.48 ± 0.29
Basal Forebrain8.55 ± 0.14
Basal Part of Pons8.62 ± 0.21
Cerebellar Cortex8.4 ± 0.13
Cerebellar Nuclei8.43 ± 0.16
Claustrum8.6 ± 0.18
Epithalamus8.37 ± 0.13
Frontal Lobe8.67 ± 0.18
Globus Pallidus8.57 ± 0.25
Hypothalamus8.55 ± 0.21
Insula8.7 ± 0.16
Limbic Lobe8.63 ± 0.26
Mesencephalon8.53 ± 0.23
Myelencephalon8.55 ± 0.23
Occipital Lobe8.39 ± 0.22
Parietal Lobe8.54 ± 0.26
Pontine Tegmentum8.54 ± 0.24
Striatum8.34 ± 0.29
Subthalamus8.46 ± 0.19
Temporal Lobe8.64 ± 0.2
Thalamus8.46 ± 0.16
White Matter8.74 ± 0.1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
1810055E12RikCBCerebellum0.87
1.67
1810055E12RikCTXCerebral cortex0.22
0.34
1810055E12RikHIPHippocampal region0.11
0.24
1810055E12RikHPFHippocampal formation0.28
0.6
1810055E12RikHYHypothalamus1.36
2.05
1810055E12RikLSXLateral septal complex0.25
0.19
1810055E12RikMBMidbrain0.15
0.22
1810055E12RikMYMedulla1.98
4.42
1810055E12RikOLFOlfactory bulb0.68
1.81
1810055E12RikPPons0.21
0.42
1810055E12RikPALPallidum0.12
0.08
1810055E12RikRHPRetrohippocampal region0.66
1.3
1810055E12RiksAMYStriatum-like amygdalar nuclei0.5
0.49
1810055E12RikSTRStriatum0.25
0.32
1810055E12RikSTRdStriatum dorsal region0.15
0.29
1810055E12RikSTRvStriatum ventral region0.42
0.39
1810055E12RikTHThalamus0.23
0.26
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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