AutismKB 2.0

Annotation Detail for LTBP1


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Basic Information Top
Gene Symbol:LTBP1 ( MGC163161 )
Gene Full Name: latent transforming growth factor beta binding protein 1
Band: 2p22.3
Quick LinksEntrez ID:4052; OMIM: 150390; Uniprot ID:LTBP1_HUMAN; ENSEMBL ID: ENSG00000049323; HGNC ID: 6714
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst2 / 6231932
fetus55 / 56401297
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult142 / 193912173
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma21 / 82823253
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor9 / 26384534
glioma0 / 1068830 
head and neck tumor8 / 13630258
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia10 / 97250102
normal244 / 336030772
ovarian tumor5 / 7668265
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood4 / 12347832
bone20 / 71655279
bone marrow5 / 48801102
brain18 / 110098916
cervix0 / 481710 
connective tissue17 / 149255113
ear4 / 16212246
embryonic tissue21 / 21572297
esophagus0 / 202090 
eye17 / 21105480
heart20 / 89626223
intestine9 / 23447238
kidney14 / 21177766
larynx0 / 241450 
liver4 / 20774319
lung21 / 33697462
lymph0 / 442700 
lymph node1 / 9161010
mammary gland14 / 15327191
mouth3 / 6705244
muscle5 / 10771546
nerve0 / 157680 
ovary6 / 10205158
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland2 / 16585120
placenta18 / 28082564
prostate41 / 189345216
salivary gland0 / 201550 
skin8 / 21057437
spleen1 / 5395218
stomach5 / 9661951
testis5 / 33044215
thymus0 / 811310 
thyroid5 / 47473105
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus19 / 23287881
vascular17 / 51780328
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202728_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.15
Adipocyte6.15
AdrenalCortex6.6
Adrenalgland5.3
Amygdala6.5
Appendix6.25
AtrioventricularNode5.1
BDCA4+_DentriticCells5.95
Bonemarrow6.3
BronchialEpithelialCells6.2
CD105+_Endothelial68.55
CD14+_Monocytes6.4
CD19+_BCells(neg._sel.)6.45
CD33+_Myeloid7.95
CD34+42.55
CD4+_Tcells6.8
CD56+_NKCells7.25
CD71+_EarlyErythroid55.15
CD8+_Tcells5.95
CardiacMyocytes18.9
Caudatenucleus5.5
Cerebellum5.05
CerebellumPeduncles7.05
CiliaryGanglion4.5
CingulateCortex6.3
Colorectaladenocarcinoma6.2
DorsalRootGanglion4.85
FetalThyroid6.05
Fetalbrain5.95
Fetalliver5.6
Fetallung5.3
GlobusPallidus4.5
Heart12.15
Hypothalamus6.7
Kidney5.2
Leukemia_chronicMyelogenousK-5625.5
Leukemia_promyelocytic-HL-605.5
Leukemialymphoblastic(MOLT-4)5
Liver8.3
Lung7
Lymphnode5.2
Lymphoma_burkitts(Daudi)7.95
Lymphoma_burkitts(Raji)9.45
MedullaOblongata5.6
OccipitalLobe5.6
OlfactoryBulb4.9
Ovary4.45
Pancreas4.85
PancreaticIslet6.35
ParietalLobe6.65
Pituitary7.15
Placenta33.3
Pons6.05
PrefrontalCortex7.15
Prostate8.55
Salivarygland4.95
SkeletalMuscle7.3
Skin4.85
SmoothMuscle121.45
Spinalcord6.45
SubthalamicNucleus5.65
SuperiorCervicalGanglion7.15
TemporalLobe5.8
Testis5.3
TestisGermCell5.2
TestisIntersitial5.25
TestisLeydigCell6.15
TestisSeminiferousTubule5.35
Thalamus6.45
Thymus4.9
Thyroid7.85
Tongue6.25
Tonsil7.3
Trachea5.1
TrigeminalGanglion6.25
Uterus5.95
UterusCorpus6.8
WholeBlood6.7
Wholebrain5.15
colon7.4
pineal_day7.72
pineal_night7.58
retina7.6
small_intestine19.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15027_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.98 ± 0.8
Basal Forebrain2.62 ± 0.3
Basal Part of Pons2.21 ± 0.42
Cerebellar Cortex2.11 ± 0.38
Cerebellar Nuclei3.1 ± 0.84
Claustrum3.25 ± 0.49
Epithalamus3.36 ± 0.7
Frontal Lobe2.71 ± 0.71
Globus Pallidus4.14 ± 0.43
Hypothalamus2.53 ± 0.73
Insula2.82 ± 0.71
Limbic Lobe2.7 ± 0.78
Mesencephalon2.97 ± 0.75
Myelencephalon2.82 ± 0.71
Occipital Lobe2.95 ± 0.73
Parietal Lobe2.76 ± 0.79
Pontine Tegmentum2.79 ± 0.78
Striatum3.49 ± 0.72
Subthalamus2.74 ± 0.82
Temporal Lobe2.45 ± 0.77
Thalamus2.67 ± 0.64
White Matter3.46 ± 0.86
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ltbp1CBCerebellum1.06
1.57
Ltbp1CTXCerebral cortex0.68
0.88
Ltbp1HIPHippocampal region0.51
0.61
Ltbp1HPFHippocampal formation0.48
0.58
Ltbp1HYHypothalamus0.08
0.2
Ltbp1LSXLateral septal complex1.08
2.65
Ltbp1MBMidbrain0.99
1.93
Ltbp1MYMedulla0.58
0.73
Ltbp1OLFOlfactory bulb0.94
2.06
Ltbp1PPons0.4
0.43
Ltbp1PALPallidum0.53
0.63
Ltbp1RHPRetrohippocampal region0.38
0.47
Ltbp1sAMYStriatum-like amygdalar nuclei0.72
0.68
Ltbp1STRStriatum0.38
0.53
Ltbp1STRdStriatum dorsal region0.23
0.31
Ltbp1STRvStriatum ventral region0.35
0.25
Ltbp1THThalamus0.79
1.06
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00376942 19 1313 1331 VQEGYTCDCFDGYHLDTAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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