AutismKB 2.0

Annotation Detail for LTBP2


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Basic Information Top
Gene Symbol:LTBP2 ( C14orf141,GLC3D,LTBP3,MSTP031 )
Gene Full Name: latent transforming growth factor beta binding protein 2
Band: 14q24.3
Quick LinksEntrez ID:4053; OMIM: 602091; Uniprot ID:LTBP2_HUMAN; ENSEMBL ID: ENSG00000119681; HGNC ID: 6715
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst4 / 6231964
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult103 / 193912153
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma14 / 82823169
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma3 / 10688328
head and neck tumor8 / 13630258
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia9 / 9725092
normal147 / 336030743
ovarian tumor1 / 7668213
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone14 / 71655195
bone marrow0 / 488010 
brain11 / 11009899
cervix0 / 481710 
connective tissue17 / 149255113
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus1 / 2020949
eye22 / 211054104
heart4 / 8962644
intestine4 / 23447217
kidney7 / 21177733
larynx0 / 241450 
liver1 / 2077434
lung35 / 336974103
lymph0 / 442700 
lymph node0 / 916100 
mammary gland10 / 15327165
mouth0 / 670520 
muscle1 / 1077159
nerve3 / 15768190
ovary3 / 10205129
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta9 / 28082532
prostate9 / 18934547
salivary gland0 / 201550 
skin11 / 21057452
spleen0 / 539520 
stomach1 / 9661910
testis5 / 33044215
thymus0 / 811310 
thyroid9 / 47473189
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus5 / 23287821
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204682_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.2
Adipocyte245.2
AdrenalCortex5.95
Adrenalgland5.65
Amygdala7.9
Appendix19.65
AtrioventricularNode25.35
BDCA4+_DentriticCells5.5
Bonemarrow7.25
BronchialEpithelialCells33.05
CD105+_Endothelial6.75
CD14+_Monocytes5.35
CD19+_BCells(neg._sel.)5.4
CD33+_Myeloid6.45
CD34+6.35
CD4+_Tcells5.45
CD56+_NKCells6.05
CD71+_EarlyErythroid8.35
CD8+_Tcells4.95
CardiacMyocytes75.25
Caudatenucleus5.3
Cerebellum5.65
CerebellumPeduncles9.15
CiliaryGanglion77.3
CingulateCortex8.3
Colorectaladenocarcinoma23.9
DorsalRootGanglion29.15
FetalThyroid46.5
Fetalbrain5.05
Fetalliver7.6
Fetallung14.9
GlobusPallidus4.95
Heart16.3
Hypothalamus6.6
Kidney8
Leukemia_chronicMyelogenousK-5625.05
Leukemia_promyelocytic-HL-605.25
Leukemialymphoblastic(MOLT-4)4.4
Liver9.75
Lung584.05
Lymphnode42.05
Lymphoma_burkitts(Daudi)7.25
Lymphoma_burkitts(Raji)7
MedullaOblongata6.15
OccipitalLobe5.25
OlfactoryBulb22.7
Ovary4.95
Pancreas12
PancreaticIslet11.4
ParietalLobe5.75
Pituitary10.9
Placenta54.45
Pons16.65
PrefrontalCortex7.05
Prostate8.95
Salivarygland13.75
SkeletalMuscle8.3
Skin7.95
SmoothMuscle600.2
Spinalcord10.95
SubthalamicNucleus4.8
SuperiorCervicalGanglion32
TemporalLobe7.1
Testis10.9
TestisGermCell18.85
TestisIntersitial6.45
TestisLeydigCell7
TestisSeminiferousTubule7.4
Thalamus5.25
Thymus6.5
Thyroid186.95
Tongue30.75
Tonsil7.5
Trachea29.75
TrigeminalGanglion54.55
Uterus42
UterusCorpus93.1
WholeBlood6.95
Wholebrain4.35
colon6.1
pineal_day6.44
pineal_night6.54
retina223.075
small_intestine7.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P176173
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.14 ± 0.69
Basal Forebrain3.71 ± 0.48
Basal Part of Pons4.15 ± 0.35
Cerebellar Cortex3.92 ± 0.6
Cerebellar Nuclei4.17 ± 0.49
Claustrum4.13 ± 0.74
Epithalamus3.5 ± 0.43
Frontal Lobe3.87 ± 0.62
Globus Pallidus4.3 ± 0.64
Hypothalamus3.7 ± 0.79
Insula3.64 ± 0.97
Limbic Lobe4.08 ± 0.63
Mesencephalon3.96 ± 0.59
Myelencephalon3.97 ± 0.65
Occipital Lobe4.11 ± 0.56
Parietal Lobe3.78 ± 0.68
Pontine Tegmentum3.69 ± 0.78
Striatum4.19 ± 0.61
Subthalamus3.58 ± 0.8
Temporal Lobe3.86 ± 0.69
Thalamus3.87 ± 0.58
White Matter4.46 ± 0.52
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
LTBP2_HUMAN_239 9 239 247 WAERSPNLR PRIDE
PAp00136825 13 55 67 RPGGSYPAAAAAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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