AutismKB 2.0

Annotation Detail for LTBP3


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Basic Information Top
Gene Symbol:LTBP3 ( DKFZp586M2123,FLJ33431,FLJ39893,FLJ42533,FLJ44138,FLJ45576,LTBP-3,LTBP2,STHAG6,pp6425 )
Gene Full Name: latent transforming growth factor beta binding protein 3
Band: 11q13.1
Quick LinksEntrez ID:4054; OMIM: 602090; Uniprot ID:LTBP3_HUMAN; ENSEMBL ID: ENSG00000168056; HGNC ID: 6716
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst3 / 6231948
fetus32 / 56401256
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult193 / 193912199
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma3 / 17475171
breast (mammary gland) tumor11 / 94178116
cervical tumor0 / 343660 
chondrosarcoma17 / 82823205
colorectal tumor24 / 114246210
esophageal tumor0 / 172900 
gastrointestinal tumor10 / 11936983
germ cell tumor18 / 26384568
glioma20 / 106883187
head and neck tumor13 / 13630295
kidney tumor7 / 68959101
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor5 / 10312748
lymphoma2 / 7175527
non-neoplasia16 / 97250164
normal242 / 336030772
ovarian tumor12 / 76682156
pancreatic tumor25 / 104616238
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer17 / 102680165
retinoblastoma1 / 4635621
skin tumor13 / 124949104
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites2 / 4001549
bladder0 / 297570 
blood1 / 1234788
bone8 / 71655111
bone marrow1 / 4880120
brain91 / 110098982
cervix0 / 481710 
connective tissue28 / 149255187
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye49 / 211054232
heart4 / 8962644
intestine33 / 234472140
kidney20 / 21177794
larynx1 / 2414541
liver1 / 2077434
lung25 / 33697474
lymph0 / 442700 
lymph node1 / 9161010
mammary gland12 / 15327178
mouth6 / 6705289
muscle2 / 10771518
nerve3 / 15768190
ovary16 / 102051156
pancreas28 / 214812130
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta12 / 28082542
prostate29 / 189345153
salivary gland0 / 201550 
skin15 / 21057471
spleen9 / 53952166
stomach10 / 96619103
testis15 / 33044245
thymus14 / 81131172
thyroid8 / 47473168
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus23 / 23287898
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219922_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.9
Adipocyte47.8
AdrenalCortex50.25
Adrenalgland38.15
Amygdala164.15
Appendix31.25
AtrioventricularNode25
BDCA4+_DentriticCells63.3
Bonemarrow20.95
BronchialEpithelialCells17.65
CD105+_Endothelial58.35
CD14+_Monocytes16.4
CD19+_BCells(neg._sel.)41.35
CD33+_Myeloid22.1
CD34+102.65
CD4+_Tcells619.15
CD56+_NKCells139.95
CD71+_EarlyErythroid25.35
CD8+_Tcells644.2
CardiacMyocytes85.7
Caudatenucleus62.15
Cerebellum26.3
CerebellumPeduncles37.5
CiliaryGanglion22.4
CingulateCortex24.95
Colorectaladenocarcinoma1046.25
DorsalRootGanglion26.8
FetalThyroid209.9
Fetalbrain36.35
Fetalliver22.45
Fetallung192.95
GlobusPallidus22.95
Heart177.15
Hypothalamus75.4
Kidney28.15
Leukemia_chronicMyelogenousK-56226.95
Leukemia_promyelocytic-HL-609.9
Leukemialymphoblastic(MOLT-4)15.55
Liver74.4
Lung559.9
Lymphnode99.95
Lymphoma_burkitts(Daudi)21.4
Lymphoma_burkitts(Raji)37.55
MedullaOblongata27.55
OccipitalLobe31.45
OlfactoryBulb170.45
Ovary43.45
Pancreas30.15
PancreaticIslet33.7
ParietalLobe32.5
Pituitary82.5
Placenta259.7
Pons29.6
PrefrontalCortex178.85
Prostate490.45
Salivarygland20.25
SkeletalMuscle30.2
Skin20.4
SmoothMuscle102.9
Spinalcord226.75
SubthalamicNucleus30.25
SuperiorCervicalGanglion29.65
TemporalLobe16.45
Testis29.1
TestisGermCell26.6
TestisIntersitial22.45
TestisLeydigCell31.4
TestisSeminiferousTubule18.85
Thalamus22.2
Thymus64.8
Thyroid2140.65
Tongue37.05
Tonsil32.8
Trachea38.4
TrigeminalGanglion35.3
Uterus371.75
UterusCorpus55.75
WholeBlood19.35
Wholebrain58.9
colon37.5
pineal_day272.24
pineal_night243.32
retina486.45
small_intestine32.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P352291
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.48 ± 0.37
Basal Forebrain6.37 ± 0.22
Basal Part of Pons6.18 ± 0.27
Cerebellar Cortex6.64 ± 0.23
Cerebellar Nuclei6.44 ± 0.32
Claustrum6.28 ± 0.4
Epithalamus6.73 ± 0.17
Frontal Lobe6.36 ± 0.33
Globus Pallidus6.2 ± 0.37
Hypothalamus6.33 ± 0.24
Insula6.46 ± 0.27
Limbic Lobe6.38 ± 0.4
Mesencephalon6.44 ± 0.35
Myelencephalon6.41 ± 0.36
Occipital Lobe6.58 ± 0.31
Parietal Lobe6.38 ± 0.29
Pontine Tegmentum6.4 ± 0.3
Striatum6.39 ± 0.29
Subthalamus6.32 ± 0.42
Temporal Lobe6.41 ± 0.3
Thalamus6.35 ± 0.28
White Matter6.92 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ltbp3CBCerebellum26.1
24.64
Ltbp3CTXCerebral cortex21.57
9.27
Ltbp3HIPHippocampal region6.91
4.64
Ltbp3HPFHippocampal formation9.38
5.09
Ltbp3HYHypothalamus52.86
24.14
Ltbp3LSXLateral septal complex5.79
2.26
Ltbp3MBMidbrain64.43
39.87
Ltbp3MYMedulla59.32
43.31
Ltbp3OLFOlfactory bulb24.64
11.94
Ltbp3PPons57.33
39.29
Ltbp3PALPallidum43.89
23.58
Ltbp3RHPRetrohippocampal region12.57
5.29
Ltbp3sAMYStriatum-like amygdalar nuclei38.25
15.91
Ltbp3STRStriatum10.14
4.43
Ltbp3STRdStriatum dorsal region4.24
2.09
Ltbp3STRvStriatum ventral region14.94
5.71
Ltbp3THThalamus26.78
13.52
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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