AutismKB 2.0

Annotation Detail for MAG


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Basic Information Top
Gene Symbol:MAG ( GMA,S-MAG,SIGLEC-4A,SIGLEC4A )
Gene Full Name: myelin associated glycoprotein
Band: 19q13.1
Quick LinksEntrez ID:4099; OMIM: 159460; Uniprot ID:MAG_HUMAN; ENSEMBL ID: ENSG00000105695; HGNC ID: 6783
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult75 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor74 / 689591073
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma6 / 7175583
non-neoplasia40 / 97250411
normal1029 / 3360307306
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain1072 / 1100989973
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney74 / 211777349
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 216617_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.1
Adipocyte7.55
AdrenalCortex10.9
Adrenalgland7.75
Amygdala235.85
Appendix10.3
AtrioventricularNode9.5
BDCA4+_DentriticCells7.65
Bonemarrow9.4
BronchialEpithelialCells7.25
CD105+_Endothelial8.85
CD14+_Monocytes8.25
CD19+_BCells(neg._sel.)7.75
CD33+_Myeloid10.15
CD34+8.7
CD4+_Tcells7.5
CD56+_NKCells9.25
CD71+_EarlyErythroid8
CD8+_Tcells6.65
CardiacMyocytes23.65
Caudatenucleus142.8
Cerebellum20.9
CerebellumPeduncles90.4
CiliaryGanglion10.95
CingulateCortex95.45
Colorectaladenocarcinoma21
DorsalRootGanglion8.1
FetalThyroid8.45
Fetalbrain7.95
Fetalliver7
Fetallung5.55
GlobusPallidus41.7
Heart61
Hypothalamus133.95
Kidney8.15
Leukemia_chronicMyelogenousK-5627.15
Leukemia_promyelocytic-HL-607.05
Leukemialymphoblastic(MOLT-4)5.8
Liver12.85
Lung8.2
Lymphnode6.2
Lymphoma_burkitts(Daudi)10.4
Lymphoma_burkitts(Raji)13.1
MedullaOblongata174.15
OccipitalLobe180.75
OlfactoryBulb33.9
Ovary6.15
Pancreas5.75
PancreaticIslet8.05
ParietalLobe165.95
Pituitary9.15
Placenta7.4
Pons84.8
PrefrontalCortex333.2
Prostate8.6
Salivarygland7.1
SkeletalMuscle17.65
Skin8.4
SmoothMuscle8.55
Spinalcord561.4
SubthalamicNucleus43.05
SuperiorCervicalGanglion16.1
TemporalLobe20.7
Testis7.05
TestisGermCell7.15
TestisIntersitial7
TestisLeydigCell8.45
TestisSeminiferousTubule6.25
Thalamus150.4
Thymus5.5
Thyroid9.45
Tongue8.9
Tonsil8.35
Trachea6.35
TrigeminalGanglion10.9
Uterus6.55
UterusCorpus7.95
WholeBlood7.8
Wholebrain223.35
colon8.85
pineal_day13.52
pineal_night13.24
retina117.325
small_intestine7.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14405_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.8 ± 0.6
Basal Forebrain6.47 ± 0.61
Basal Part of Pons6.76 ± 0.85
Cerebellar Cortex5.77 ± 0.45
Cerebellar Nuclei7.21 ± 0.54
Claustrum6.24 ± 0.65
Epithalamus5.75 ± 1
Frontal Lobe6.33 ± 0.92
Globus Pallidus7.98 ± 0.35
Hypothalamus5.74 ± 0.56
Insula5.45 ± 0.83
Limbic Lobe5.99 ± 0.8
Mesencephalon6.33 ± 0.83
Myelencephalon6.39 ± 0.76
Occipital Lobe6.11 ± 0.8
Parietal Lobe6.13 ± 0.86
Pontine Tegmentum6.3 ± 0.63
Striatum6.79 ± 0.66
Subthalamus6.17 ± 0.25
Temporal Lobe6 ± 0.67
Thalamus6.7 ± 0.52
White Matter9.19 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MagCBCerebellum92.64
100
MagCTXCerebral cortex61.95
62.59
MagHIPHippocampal region66.65
83.1
MagHPFHippocampal formation73.46
83.99
MagHYHypothalamus100
100
MagLSXLateral septal complex100
99.17
MagMBMidbrain100
100
MagMYMedulla100
100
MagOLFOlfactory bulb56.43
60.3
MagPPons100
100
MagPALPallidum100
100
MagRHPRetrohippocampal region82.8
83.79
MagsAMYStriatum-like amygdalar nuclei83.83
76.52
MagSTRStriatum95.2
94.42
MagSTRdStriatum dorsal region100
100
MagSTRvStriatum ventral region61.24
55.05
MagTHThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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