AutismKB 2.0

Annotation Detail for MAOA


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Basic Information Top
Gene Symbol:MAOA ( - )
Gene Full Name: monoamine oxidase A
Band: Xp11.3
Quick LinksEntrez ID:4128; OMIM: 309850; Uniprot ID:AOFA_HUMAN; ENSEMBL ID: ENSG00000189221; HGNC ID: 6833
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus43 / 56401276
neonate0 / 310970 
infant0 / 236200 
juvenile8 / 55556143
adult163 / 193912184
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma6 / 17475343
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor6 / 11424652
esophageal tumor3 / 17290173
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma2 / 10688318
head and neck tumor12 / 13630288
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor11 / 96359114
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal298 / 336030788
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer8 / 10268077
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue6 / 13106457
adrenal gland0 / 331970 
ascites0 / 400150 
bladder6 / 29757201
blood0 / 1234780 
bone1 / 7165513
bone marrow1 / 4880120
brain80 / 110098972
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus3 / 20209148
eye5 / 21105423
heart8 / 8962689
intestine30 / 234472127
kidney15 / 21177770
larynx0 / 241450 
liver21 / 207743101
lung21 / 33697462
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth3 / 6705244
muscle8 / 10771574
nerve9 / 15768570
ovary4 / 10205139
pancreas7 / 21481232
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta78 / 280825277
prostate20 / 189345105
salivary gland2 / 2015599
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis5 / 33044215
thymus6 / 8113173
thyroid11 / 47473231
tonsil0 / 169990 
trachea24 / 52413457
umbilical cord0 / 136800 
uterus16 / 23287868
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204388_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.35
Adipocyte214.1
AdrenalCortex27.25
Adrenalgland18.4
Amygdala16.1
Appendix19.7
AtrioventricularNode30.05
BDCA4+_DentriticCells11.8
Bonemarrow21.2
BronchialEpithelialCells60.65
CD105+_Endothelial15.25
CD14+_Monocytes17.6
CD19+_BCells(neg._sel.)16.55
CD33+_Myeloid20.25
CD34+18.9
CD4+_Tcells13.35
CD56+_NKCells16.4
CD71+_EarlyErythroid16.4
CD8+_Tcells10.95
CardiacMyocytes35.9
Caudatenucleus14.75
Cerebellum12.9
CerebellumPeduncles20.15
CiliaryGanglion30.15
CingulateCortex18.25
Colorectaladenocarcinoma14.75
DorsalRootGanglion23.65
FetalThyroid28.05
Fetalbrain16.1
Fetalliver22.55
Fetallung43.15
GlobusPallidus14.3
Heart30.6
Hypothalamus19.65
Kidney60
Leukemia_chronicMyelogenousK-56213.8
Leukemia_promyelocytic-HL-6014.2
Leukemialymphoblastic(MOLT-4)12.65
Liver61.4
Lung62.05
Lymphnode13.65
Lymphoma_burkitts(Daudi)20.8
Lymphoma_burkitts(Raji)23.85
MedullaOblongata14.3
OccipitalLobe14.5
OlfactoryBulb13.85
Ovary37.6
Pancreas37.55
PancreaticIslet85.7
ParietalLobe21.85
Pituitary19.9
Placenta423.9
Pons19.05
PrefrontalCortex20.85
Prostate42.25
Salivarygland47.35
SkeletalMuscle31.05
Skin22.5
SmoothMuscle17.8
Spinalcord17.45
SubthalamicNucleus38.75
SuperiorCervicalGanglion31.15
TemporalLobe15.25
Testis13.95
TestisGermCell12.8
TestisIntersitial15.55
TestisLeydigCell26.05
TestisSeminiferousTubule13.85
Thalamus18.2
Thymus12.85
Thyroid67.05
Tongue19.15
Tonsil15.75
Trachea30.75
TrigeminalGanglion24.5
Uterus17.35
UterusCorpus16.65
WholeBlood14.6
Wholebrain11.5
colon311.9
pineal_day16.48
pineal_night17.12
retina19.475
small_intestine386.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_601_PI417557136
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.82 ± 0.2
Basal Forebrain7.6 ± 0.19
Basal Part of Pons6.94 ± 0.22
Cerebellar Cortex7.02 ± 0.27
Cerebellar Nuclei7.18 ± 0.39
Claustrum7.35 ± 0.42
Epithalamus7.41 ± 0.81
Frontal Lobe7.49 ± 0.48
Globus Pallidus9.09 ± 0.54
Hypothalamus8.04 ± 0.42
Insula7.66 ± 0.34
Limbic Lobe7.67 ± 0.63
Mesencephalon7.76 ± 0.43
Myelencephalon7.62 ± 0.56
Occipital Lobe7.91 ± 0.59
Parietal Lobe7.65 ± 0.49
Pontine Tegmentum8.04 ± 0.65
Striatum8.09 ± 0.42
Subthalamus7.59 ± 0.41
Temporal Lobe7.56 ± 0.46
Thalamus8.02 ± 0.42
White Matter6.24 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MaoaCBCerebellum3.47
4.57
MaoaCTXCerebral cortex1.23
1.42
MaoaHIPHippocampal region1.47
2.27
MaoaHPFHippocampal formation1.41
1.95
MaoaHYHypothalamus1.58
1.62
MaoaLSXLateral septal complex1.45
1.56
MaoaMBMidbrain2.84
3.67
MaoaMYMedulla2.83
4.04
MaoaOLFOlfactory bulb1.32
1.81
MaoaPPons5.8
10.34
MaoaPALPallidum1.69
1.75
MaoaRHPRetrohippocampal region1.45
1.69
MaoasAMYStriatum-like amygdalar nuclei0.6
0.78
MaoaSTRStriatum0.9
0.88
MaoaSTRdStriatum dorsal region1.01
1.01
MaoaSTRvStriatum ventral region0.58
0.41
MaoaTHThalamus3.67
3.47
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
AOFA_HUMAN_218 12 218 229 KFVGGSGQVSER PRIDE
AOFA_HUMAN_83 8 83 90 ELGIETYK PRIDE
PAp00005179 28 240 267 LNHPVTHVDQSSDNIIIETLNHEHYECK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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