AutismKB 2.0

Annotation Detail for MAOB


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MAOB ( MGC26382 )
Gene Full Name: monoamine oxidase B
Band: Xp11.3
Quick LinksEntrez ID:4129; OMIM: 309860; Uniprot ID:AOFB_HUMAN; ENSEMBL ID: ENSG00000069535; HGNC ID: 6834
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult69 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor9 / 26384534
glioma6 / 10688356
head and neck tumor2 / 13630214
kidney tumor6 / 6895987
leukemia0 / 958420 
liver tumor5 / 9635951
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal140 / 336030741
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain74 / 110098967
cervix1 / 4817120
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart3 / 8962633
intestine6 / 23447225
kidney19 / 21177789
larynx0 / 241450 
liver10 / 20774348
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth1 / 6705214
muscle4 / 10771537
nerve4 / 15768253
ovary3 / 10205129
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta5 / 28082517
prostate9 / 18934547
salivary gland1 / 2015549
skin1 / 2105744
spleen1 / 5395218
stomach2 / 9661920
testis6 / 33044218
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus19 / 23287881
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204041_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.5
Adipocyte9.7
AdrenalCortex12.25
Adrenalgland11.1
Amygdala101.8
Appendix9.9
AtrioventricularNode7.4
BDCA4+_DentriticCells6.15
Bonemarrow9.55
BronchialEpithelialCells8.95
CD105+_Endothelial9.9
CD14+_Monocytes6.5
CD19+_BCells(neg._sel.)10.4
CD33+_Myeloid6.35
CD34+9.95
CD4+_Tcells10.7
CD56+_NKCells8.5
CD71+_EarlyErythroid3.8
CD8+_Tcells8.15
CardiacMyocytes12.1
Caudatenucleus70.5
Cerebellum8.05
CerebellumPeduncles10.45
CiliaryGanglion6.9
CingulateCortex10.2
Colorectaladenocarcinoma10.55
DorsalRootGanglion7.55
FetalThyroid9.5
Fetalbrain9.05
Fetalliver51.05
Fetallung8.4
GlobusPallidus9.85
Heart23.9
Hypothalamus381.2
Kidney33.85
Leukemia_chronicMyelogenousK-5628.85
Leukemia_promyelocytic-HL-608.65
Leukemialymphoblastic(MOLT-4)7.8
Liver55.8
Lung20.7
Lymphnode8.6
Lymphoma_burkitts(Daudi)12.4
Lymphoma_burkitts(Raji)13.45
MedullaOblongata10.05
OccipitalLobe10.55
OlfactoryBulb21.7
Ovary11.85
Pancreas7.9
PancreaticIslet10.5
ParietalLobe10.55
Pituitary16.5
Placenta10.4
Pons10.6
PrefrontalCortex121.45
Prostate19.55
Salivarygland13.25
SkeletalMuscle11.35
Skin7.5
SmoothMuscle11.1
Spinalcord198.4
SubthalamicNucleus9.1
SuperiorCervicalGanglion10.85
TemporalLobe13.65
Testis8.85
TestisGermCell9.25
TestisIntersitial8.2
TestisLeydigCell9.65
TestisSeminiferousTubule8.35
Thalamus12.45
Thymus7.8
Thyroid12.45
Tongue9.8
Tonsil7.85
Trachea8.2
TrigeminalGanglion9.65
Uterus131.2
UterusCorpus8.8
WholeBlood10.65
Wholebrain15.4
colon9.95
pineal_day73.62
pineal_night18.36
retina66.825
small_intestine156.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_69_PI417557136
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.71 ± 0.36
Basal Forebrain5.63 ± 0.4
Basal Part of Pons5.33 ± 0.39
Cerebellar Cortex5.04 ± 0.29
Cerebellar Nuclei4.95 ± 0.38
Claustrum4.59 ± 0.88
Epithalamus6.93 ± 0.61
Frontal Lobe5.68 ± 0.51
Globus Pallidus6.61 ± 0.26
Hypothalamus6.93 ± 0.71
Insula5.84 ± 0.48
Limbic Lobe5.74 ± 0.65
Mesencephalon5.82 ± 0.8
Myelencephalon5.61 ± 0.72
Occipital Lobe5.28 ± 0.63
Parietal Lobe5.65 ± 0.71
Pontine Tegmentum5.7 ± 0.68
Striatum6.3 ± 0.61
Subthalamus5.96 ± 0.41
Temporal Lobe5.62 ± 0.44
Thalamus5.67 ± 0.36
White Matter4.15 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MaobCBCerebellum5.07
5.9
MaobCTXCerebral cortex2.39
1.95
MaobHIPHippocampal region1.26
1.03
MaobHPFHippocampal formation2.6
2.16
MaobHYHypothalamus2.95
3.99
MaobLSXLateral septal complex2.27
2.33
MaobMBMidbrain3.03
4.93
MaobMYMedulla11.45
14.39
MaobOLFOlfactory bulb2.87
2.1
MaobPPons5.95
6.81
MaobPALPallidum1.56
1.5
MaobRHPRetrohippocampal region4.42
3.32
MaobsAMYStriatum-like amygdalar nuclei2.21
1.53
MaobSTRStriatum5.33
4.66
MaobSTRdStriatum dorsal region5.64
5.12
MaobSTRvStriatum ventral region7.06
5.42
MaobTHThalamus18.28
20.92
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
AOFB_HUMAN_101 20 101 120 GPFPPVWNPITYLDHNNFWR PRIDE
AOFB_HUMAN_128 9 128 136 EIPSDAPWK PRIDE
AOFB_HUMAN_198 11 198 208 IISTTNGGQER PRIDE
AOFB_HUMAN_209 12 209 220 KFVGGSGQVSER PRIDE
AOFB_HUMAN_210 11 210 220 FVGGSGQVSER PRIDE
AOFB_HUMAN_22 15 22 36 LLHDSGLNVVVLEAR PRIDE
AOFB_HUMAN_221 8 221 228 IMDLLGDR PRIDE
AOFB_HUMAN_229 14 229 242 VKLERPVIYIDQTR PRIDE
AOFB_HUMAN_231 12 231 242 LERPVIYIDQTR PRIDE
AOFB_HUMAN_243 16 243 258 ENVLVETLNHEMYEAK PRIDE
AOFB_HUMAN_289 8 289 296 VPLGSVIK PRIDE
AOFB_HUMAN_364 7 364 370 LCELYAK PRIDE
AOFB_HUMAN_371 16 371 386 VLGSLEALEPVHYEEK PRIDE
AOFB_HUMAN_421 25 421 445 IYFAGTETATHWSGYMEGAVEAGER PRIDE
AOFB_HUMAN_43 5 43 47 TYTLR PRIDE
AOFB_HUMAN_457 28 457 484 IPEDEIWQSEPESVDVPAQPITTTFLER PRIDE
AOFB_HUMAN_485 10 485 494 HLPSVPGLLR PRIDE
AOFB_HUMAN_53 15 53 67 YVDLGGSYVGPTQNR PRIDE
AOFB_HUMAN_74 8 74 81 ELGLETYK PRIDE
PAp00010612 8 363 370 KLCELYAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved