AutismKB 2.0

Annotation Detail for MAP1B


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Basic Information Top
Gene Symbol:MAP1B ( DKFZp686E1099,DKFZp686F1345,FLJ38954,FUTSCH,MAP5 )
Gene Full Name: microtubule-associated protein 1B
Band: 5q13.2
Quick LinksEntrez ID:4131; OMIM: 157129; Uniprot ID:MAP1B_HUMAN; ENSEMBL ID: ENSG00000131711; HGNC ID: 6836
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body19 / 70761268
blastocyst6 / 6231996
fetus205 / 564012363
neonate2 / 3109764
infant5 / 23620211
juvenile8 / 55556143
adult378 / 1939121194
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma16 / 82823193
colorectal tumor1 / 1142468
esophageal tumor3 / 17290173
gastrointestinal tumor3 / 11936925
germ cell tumor44 / 263845166
glioma18 / 106883168
head and neck tumor3 / 13630222
kidney tumor19 / 68959275
leukemia3 / 9584231
liver tumor8 / 9635983
lung tumor20 / 103127193
lymphoma0 / 717550 
non-neoplasia19 / 97250195
normal762 / 3360307226
ovarian tumor6 / 7668278
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS16 / 125680127
prostate cancer13 / 102680126
retinoblastoma13 / 46356280
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood3 / 12347824
bone12 / 71655167
bone marrow3 / 4880161
brain504 / 1100989457
cervix0 / 481710 
connective tissue11 / 14925573
ear4 / 16212246
embryonic tissue39 / 215722180
esophagus3 / 20209148
eye55 / 211054260
heart8 / 8962689
intestine9 / 23447238
kidney31 / 211777146
larynx1 / 2414541
liver12 / 20774357
lung38 / 336974112
lymph0 / 442700 
lymph node2 / 9161021
mammary gland10 / 15327165
mouth1 / 6705214
muscle8 / 10771574
nerve8 / 15768507
ovary6 / 10205158
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland5 / 16585301
placenta3 / 28082510
prostate85 / 189345448
salivary gland1 / 2015549
skin8 / 21057437
spleen1 / 5395218
stomach1 / 9661910
testis16 / 33044248
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord2 / 13680146
uterus19 / 23287881
vascular12 / 51780231
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212233_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.95
Adipocyte892.9
AdrenalCortex69.15
Adrenalgland42.2
Amygdala1298.8
Appendix181.55
AtrioventricularNode77.8
BDCA4+_DentriticCells5.5
Bonemarrow5.75
BronchialEpithelialCells20.75
CD105+_Endothelial7.6
CD14+_Monocytes6.25
CD19+_BCells(neg._sel.)6.3
CD33+_Myeloid4.95
CD34+6.05
CD4+_Tcells7.35
CD56+_NKCells6
CD71+_EarlyErythroid5.45
CD8+_Tcells4.9
CardiacMyocytes458.45
Caudatenucleus824.4
Cerebellum1098.15
CerebellumPeduncles2986.7
CiliaryGanglion894.3
CingulateCortex2452.55
Colorectaladenocarcinoma13.35
DorsalRootGanglion1345.4
FetalThyroid48.35
Fetalbrain4318.6
Fetalliver6.35
Fetallung21.1
GlobusPallidus1583.3
Heart11.4
Hypothalamus2271.5
Kidney4.55
Leukemia_chronicMyelogenousK-56261.25
Leukemia_promyelocytic-HL-604.4
Leukemialymphoblastic(MOLT-4)5.1
Liver7.45
Lung8.2
Lymphnode8.75
Lymphoma_burkitts(Daudi)8.35
Lymphoma_burkitts(Raji)8.75
MedullaOblongata1579.1
OccipitalLobe2916
OlfactoryBulb502.1
Ovary27.45
Pancreas18.35
PancreaticIslet105.5
ParietalLobe3031.4
Pituitary441.85
Placenta23.75
Pons1347.8
PrefrontalCortex4543.75
Prostate102.2
Salivarygland24.1
SkeletalMuscle9.9
Skin32.35
SmoothMuscle663
Spinalcord1561.7
SubthalamicNucleus2756.05
SuperiorCervicalGanglion243.8
TemporalLobe1504.8
Testis30.1
TestisGermCell209.1
TestisIntersitial58.3
TestisLeydigCell57.05
TestisSeminiferousTubule68.75
Thalamus3712.4
Thymus5.75
Thyroid8.65
Tongue15.35
Tonsil5.6
Trachea50.05
TrigeminalGanglion657.5
Uterus126.7
UterusCorpus24.85
WholeBlood6.5
Wholebrain956.5
colon38.9
pineal_day4607.42
pineal_night3495.68
retina931.5
small_intestine43.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P879740
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.82 ± 0.35
Basal Forebrain11.6 ± 0.27
Basal Part of Pons12.25 ± 0.35
Cerebellar Cortex11.6 ± 0.32
Cerebellar Nuclei12.2 ± 0.38
Claustrum12.35 ± 0.61
Epithalamus11.13 ± 0.64
Frontal Lobe11.94 ± 0.49
Globus Pallidus12.1 ± 0.35
Hypothalamus11.81 ± 0.43
Insula11.76 ± 0.29
Limbic Lobe12.07 ± 0.42
Mesencephalon11.96 ± 0.5
Myelencephalon11.84 ± 0.46
Occipital Lobe12.13 ± 0.28
Parietal Lobe12.06 ± 0.42
Pontine Tegmentum11.91 ± 0.44
Striatum11.25 ± 0.46
Subthalamus12.31 ± 0.17
Temporal Lobe11.79 ± 0.32
Thalamus12.13 ± 0.39
White Matter11.62 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mtap1bCBCerebellum100
100
Mtap1bCTXCerebral cortex100
100
Mtap1bHIPHippocampal region100
100
Mtap1bHPFHippocampal formation100
100
Mtap1bHYHypothalamus100
100
Mtap1bLSXLateral septal complex100
100
Mtap1bMBMidbrain100
100
Mtap1bMYMedulla100
100
Mtap1bOLFOlfactory bulb100
100
Mtap1bPPons100
100
Mtap1bPALPallidum100
100
Mtap1bRHPRetrohippocampal region100
100
Mtap1bsAMYStriatum-like amygdalar nuclei100
100
Mtap1bSTRStriatum100
100
Mtap1bSTRdStriatum dorsal region100
100
Mtap1bSTRvStriatum ventral region100
100
Mtap1bTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MAP1B_HUMAN_104 22 104 125 SDVLETVVLINPSDEAVSTEVR PRIDE
MAP1B_HUMAN_1051 19 1051 1069 AAEAGGAEEQYGFLTTPTK PRIDE
MAP1B_HUMAN_1275 12 1275 1286 SVNFSLTPNEIK PRIDE
MAP1B_HUMAN_1375 19 1375 1393 ASVSPMDEPVPDSESPIEK PRIDE
MAP1B_HUMAN_1436 22 1436 1457 QGSPDQVSPVSEMTSTSLYQDK PRIDE
MAP1B_HUMAN_1461 15 1461 1475 STDFAPIKEDFGQEK PRIDE
MAP1B_HUMAN_1476 19 1476 1494 KTDDVEAMSSQPALALDER PRIDE
MAP1B_HUMAN_1477 19 1477 1495 KTDDVEAMSSQPALALDER PRIDE
MAP1B_HUMAN_1478 18 1478 1495 TDDVEAMSSQPALALDER PRIDE
MAP1B_HUMAN_1640 25 1640 1664 SEQSSMSIEFGQESPEQSLAMDFSR PRIDE
MAP1B_HUMAN_1781 9 1781 1789 SDISPLTPR PRIDE
MAP1B_HUMAN_1833 16 1833 1848 ASVLFDTMQHHLALNR PRIDE
MAP1B_HUMAN_1834 16 1834 1849 ASVLFDTMQHHLALNR PRIDE
MAP1B_HUMAN_1860 21 1860 1880 SGGKTPGDFSYAYQKPEETTR PRIDE
MAP1B_HUMAN_1897 14 1897 1910 TSDVGGYYYEKIER PRIDE
MAP1B_HUMAN_2 30 2 31 ATVVVEATEPEPSGSIANPAASTSPSLSHR PRIDE
MAP1B_HUMAN_2197 12 2197 2208 HMDPPPAPVQDR PRIDE
MAP1B_HUMAN_2200 9 2200 2208 PPPAPVQDR PRIDE
MAP1B_HUMAN_2381 18 2381 2398 SSYYVVSGNDPAAEEPSR PRIDE
MAP1B_HUMAN_2392 8 2392 2399 PAAEEPSR PRIDE
MAP1B_HUMAN_2399 10 2399 2408 AVLDALLEGK PRIDE
MAP1B_HUMAN_304 23 304 326 VDSILLTHIGDDNLPGINSMLQR PRIDE
MAP1B_HUMAN_391 10 391 400 LSMKPEPLFR PRIDE
MAP1B_HUMAN_400 14 400 413 SVGNTIDPVILFQK PRIDE
MAP1B_HUMAN_486 18 486 503 VLFPGNSTQYNILEGLEK PRIDE
MAP1B_HUMAN_506 13 506 518 HLDFLKQPLATQK PRIDE
MAP1B_HUMAN_519 12 519 530 DLTGQVPTPVVK PRIDE
MAP1B_HUMAN_54 10 54 63 AIGNIELGIR PRIDE
MAP1B_HUMAN_551 8 551 558 PLPSKSVR PRIDE
MAP1B_HUMAN_791 31 791 821 AAEAVAAAVGTGATTAAVMAAAGIAAIGPAK PRIDE
PAp00024055 23 946 968 AETEEAEEPEEDGEEHVCVSASK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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