AutismKB 2.0

Annotation Detail for MAP2


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Basic Information Top
Gene Symbol:MAP2 ( DKFZp686I2148,MAP2A,MAP2B,MAP2C )
Gene Full Name: microtubule-associated protein 2
Band: 2q34
Quick LinksEntrez ID:4133; OMIM: 157130; Uniprot ID:MAP2_HUMAN; ENSEMBL ID: ENSG00000078018; HGNC ID: 6839
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus122 / 564012216
neonate0 / 310970 
infant3 / 23620127
juvenile3 / 5555653
adult154 / 193912179
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor34 / 263845128
glioma12 / 106883112
head and neck tumor5 / 13630236
kidney tumor4 / 6895958
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia12 / 97250123
normal376 / 3360307111
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain323 / 1100989293
cervix0 / 481710 
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus1 / 2020949
eye15 / 21105471
heart3 / 8962633
intestine0 / 2344720 
kidney5 / 21177723
larynx1 / 2414541
liver3 / 20774314
lung17 / 33697450
lymph0 / 442700 
lymph node6 / 9161065
mammary gland8 / 15327152
mouth0 / 670520 
muscle16 / 107715148
nerve2 / 15768126
ovary0 / 1020510 
pancreas14 / 21481265
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta0 / 2808250 
prostate8 / 18934542
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach4 / 9661941
testis25 / 33044275
thymus1 / 8113112
thyroid3 / 4747363
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210015_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.1
Adipocyte5.2
AdrenalCortex6.9
Adrenalgland4.65
Amygdala18.6
Appendix5.7
AtrioventricularNode4.2
BDCA4+_DentriticCells5.35
Bonemarrow5.35
BronchialEpithelialCells5.4
CD105+_Endothelial6
CD14+_Monocytes5.5
CD19+_BCells(neg._sel.)5.35
CD33+_Myeloid6.55
CD34+6.45
CD4+_Tcells5.45
CD56+_NKCells5.9
CD71+_EarlyErythroid4.9
CD8+_Tcells4.85
CardiacMyocytes7.4
Caudatenucleus6.6
Cerebellum4.55
CerebellumPeduncles12.4
CiliaryGanglion4.8
CingulateCortex11.95
Colorectaladenocarcinoma5.3
DorsalRootGanglion4.3
FetalThyroid5.2
Fetalbrain23.8
Fetalliver4.65
Fetallung4.15
GlobusPallidus19
Heart7.65
Hypothalamus6.65
Kidney4.6
Leukemia_chronicMyelogenousK-5624.85
Leukemia_promyelocytic-HL-604.65
Leukemialymphoblastic(MOLT-4)4.35
Liver7.25
Lung5.6
Lymphnode4.4
Lymphoma_burkitts(Daudi)6.85
Lymphoma_burkitts(Raji)7.6
MedullaOblongata6.05
OccipitalLobe26
OlfactoryBulb4.5
Ovary3.65
Pancreas4.45
PancreaticIslet6.45
ParietalLobe20.95
Pituitary9.5
Placenta5.15
Pons12.25
PrefrontalCortex12.85
Prostate5.9
Salivarygland4.65
SkeletalMuscle7.25
Skin5.4
SmoothMuscle5.85
Spinalcord5.95
SubthalamicNucleus33
SuperiorCervicalGanglion6.45
TemporalLobe11.85
Testis5.95
TestisGermCell6.25
TestisIntersitial6.7
TestisLeydigCell5.4
TestisSeminiferousTubule5.6
Thalamus6.35
Thymus4.05
Thyroid6.35
Tongue5.5
Tonsil5.35
Trachea4.55
TrigeminalGanglion5.55
Uterus4.25
UterusCorpus4.85
WholeBlood5.65
Wholebrain5.3
colon5.35
pineal_day81.86
pineal_night91.34
retina6.8
small_intestine5.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P231483
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.99 ± 0.49
Basal Forebrain9.66 ± 0.25
Basal Part of Pons9.89 ± 0.22
Cerebellar Cortex9.16 ± 0.19
Cerebellar Nuclei9.57 ± 0.49
Claustrum9.63 ± 0.38
Epithalamus9.06 ± 0.54
Frontal Lobe9.77 ± 0.43
Globus Pallidus8.63 ± 0.79
Hypothalamus9.94 ± 0.28
Insula9.85 ± 0.32
Limbic Lobe9.79 ± 0.7
Mesencephalon9.44 ± 0.55
Myelencephalon9.45 ± 0.66
Occipital Lobe9.01 ± 0.72
Parietal Lobe9.73 ± 0.47
Pontine Tegmentum9.62 ± 0.51
Striatum9.17 ± 0.8
Subthalamus9.71 ± 0.65
Temporal Lobe9.85 ± 0.33
Thalamus9.25 ± 0.4
White Matter7.19 ± 0.56
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mtap2CBCerebellum100
100
Mtap2CTXCerebral cortex100
100
Mtap2HIPHippocampal region100
100
Mtap2HPFHippocampal formation100
100
Mtap2HYHypothalamus100
100
Mtap2LSXLateral septal complex100
100
Mtap2MBMidbrain100
100
Mtap2MYMedulla100
100
Mtap2OLFOlfactory bulb100
100
Mtap2PPons100
100
Mtap2PALPallidum100
100
Mtap2RHPRetrohippocampal region100
100
Mtap2sAMYStriatum-like amygdalar nuclei100
100
Mtap2STRStriatum100
100
Mtap2STRdStriatum dorsal region100
100
Mtap2STRvStriatum ventral region100
100
Mtap2THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00131437 25 289 313 SGTSTPTTPGSTAITPGTPPSYSSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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