AutismKB 2.0

Annotation Detail for MAP6


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Basic Information Top
Gene Symbol:MAP6 ( FLJ41346,KIAA1878,MTAP6,N-STOP,STOP )
Gene Full Name: microtubule-associated protein 6
Band: 11q13.5
Quick LinksEntrez ID:4135; OMIM: 601783; Uniprot ID:MAP6_HUMAN; ENSEMBL ID: ENSG00000171533; HGNC ID: 6868
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus49 / 56401286
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult42 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor6 / 26384522
glioma11 / 106883102
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal118 / 336030735
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain86 / 110098978
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye14 / 21105466
heart0 / 896260 
intestine0 / 2344720 
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung8 / 33697423
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve2 / 15768126
ovary0 / 1020510 
pancreas5 / 21481223
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland3 / 16585180
placenta2 / 2808257
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis10 / 33044230
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P47728
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.99 ± 0.56
Basal Forebrain8.22 ± 0.33
Basal Part of Pons8.93 ± 0.4
Cerebellar Cortex8.04 ± 0.24
Cerebellar Nuclei8.28 ± 0.33
Claustrum7.87 ± 0.5
Epithalamus9.16 ± 0.61
Frontal Lobe8.49 ± 0.41
Globus Pallidus7.39 ± 0.55
Hypothalamus8.7 ± 0.34
Insula8.61 ± 0.26
Limbic Lobe8.19 ± 0.57
Mesencephalon8.05 ± 0.41
Myelencephalon8.2 ± 0.64
Occipital Lobe7.86 ± 0.49
Parietal Lobe8.23 ± 0.49
Pontine Tegmentum8.23 ± 0.45
Striatum8.09 ± 0.62
Subthalamus8.68 ± 0.38
Temporal Lobe8.47 ± 0.44
Thalamus8.08 ± 0.43
White Matter6.33 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mtap6CBCerebellum37.44
80.37
Mtap6CTXCerebral cortex100
100
Mtap6HIPHippocampal region53.19
95.78
Mtap6HPFHippocampal formation84.19
100
Mtap6HYHypothalamus86.32
89.14
Mtap6LSXLateral septal complex100
100
Mtap6MBMidbrain92.92
100
Mtap6MYMedulla87.14
100
Mtap6OLFOlfactory bulb100
100
Mtap6PPons80.07
100
Mtap6PALPallidum82.8
99.94
Mtap6RHPRetrohippocampal region100
100
Mtap6sAMYStriatum-like amygdalar nuclei100
100
Mtap6STRStriatum69.84
63.33
Mtap6STRdStriatum dorsal region57.26
52.63
Mtap6STRvStriatum ventral region69.33
57.41
Mtap6THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00080849 11 130 140 VQRPEPSCRPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018