AutismKB 2.0

Annotation Detail for MAPT


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Basic Information Top
Gene Symbol:MAPT ( DDPAC,FLJ31424,FTDP-17,MAPTL,MGC138549,MSTD,MTBT1,MTBT2,PPND,TAU )
Gene Full Name: microtubule-associated protein tau
Band: 17q21.31
Quick LinksEntrez ID:4137; OMIM: 157140; Uniprot ID:TAU_HUMAN; ENSEMBL ID: ENSG00000186868; HGNC ID: 6893
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus114 / 564012202
neonate0 / 310970 
infant4 / 23620169
juvenile6 / 55556107
adult98 / 193912150
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor2 / 3436658
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor13 / 26384549
glioma37 / 106883346
head and neck tumor2 / 13630214
kidney tumor5 / 6895972
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor11 / 103127106
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal310 / 336030792
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain217 / 1100989197
cervix6 / 48171124
connective tissue3 / 14925520
ear2 / 16212123
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye37 / 211054175
heart0 / 896260 
intestine1 / 2344724
kidney23 / 211777108
larynx0 / 241450 
liver0 / 2077430 
lung28 / 33697483
lymph0 / 442700 
lymph node0 / 916100 
mammary gland9 / 15327158
mouth0 / 670520 
muscle12 / 107715111
nerve8 / 15768507
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate4 / 18934521
salivary gland1 / 2015549
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis9 / 33044227
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203928_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.5
Adipocyte7.05
AdrenalCortex8.9
Adrenalgland6.6
Amygdala223.35
Appendix7.4
AtrioventricularNode5.7
BDCA4+_DentriticCells7.15
Bonemarrow8.65
BronchialEpithelialCells6.7
CD105+_Endothelial7.45
CD14+_Monocytes7.5
CD19+_BCells(neg._sel.)7.35
CD33+_Myeloid8.3
CD34+8.7
CD4+_Tcells7.9
CD56+_NKCells7.55
CD71+_EarlyErythroid6.95
CD8+_Tcells6.4
CardiacMyocytes9.4
Caudatenucleus17.55
Cerebellum30.85
CerebellumPeduncles33.5
CiliaryGanglion6.25
CingulateCortex26.1
Colorectaladenocarcinoma8.3
DorsalRootGanglion5.7
FetalThyroid7.35
Fetalbrain111.05
Fetalliver6.6
Fetallung6.25
GlobusPallidus22.2
Heart15.4
Hypothalamus24.7
Kidney12.4
Leukemia_chronicMyelogenousK-5628.05
Leukemia_promyelocytic-HL-606.7
Leukemialymphoblastic(MOLT-4)6.35
Liver9.9
Lung8.55
Lymphnode6.8
Lymphoma_burkitts(Daudi)9.5
Lymphoma_burkitts(Raji)10.45
MedullaOblongata25.8
OccipitalLobe37.85
OlfactoryBulb6.25
Ovary5.15
Pancreas7.65
PancreaticIslet8.7
ParietalLobe29.15
Pituitary9.85
Placenta7.55
Pons16.75
PrefrontalCortex31.25
Prostate12.05
Salivarygland6.15
SkeletalMuscle19.2
Skin6.25
SmoothMuscle8.25
Spinalcord16.85
SubthalamicNucleus27.2
SuperiorCervicalGanglion9.6
TemporalLobe39.55
Testis11.35
TestisGermCell6.55
TestisIntersitial30.95
TestisLeydigCell14.15
TestisSeminiferousTubule15.2
Thalamus20.05
Thymus5.65
Thyroid8.55
Tongue14.65
Tonsil7.35
Trachea6.5
TrigeminalGanglion7.3
Uterus6.1
UterusCorpus6.65
WholeBlood7.8
Wholebrain163.55
colon7.45
pineal_day24.54
pineal_night17.94
retina10.75
small_intestine7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_449_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.91 ± 0.27
Basal Forebrain10.35 ± 0.3
Basal Part of Pons10.76 ± 0.21
Cerebellar Cortex10.63 ± 0.26
Cerebellar Nuclei10.08 ± 0.24
Claustrum10.86 ± 0.28
Epithalamus9.59 ± 0.67
Frontal Lobe10.68 ± 0.33
Globus Pallidus9.92 ± 0.39
Hypothalamus10.45 ± 0.43
Insula10.75 ± 0.2
Limbic Lobe10.79 ± 0.28
Mesencephalon10.5 ± 0.35
Myelencephalon10.51 ± 0.42
Occipital Lobe10.21 ± 0.4
Parietal Lobe10.6 ± 0.34
Pontine Tegmentum10.49 ± 0.4
Striatum9.82 ± 0.35
Subthalamus10.42 ± 0.06
Temporal Lobe10.81 ± 0.29
Thalamus10.46 ± 0.26
White Matter9.9 ± 0.27
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00064446 19 639 657 CGSLGNIHHKPGGGQVEVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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