AutismKB 2.0

Annotation Detail for MAX


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Basic Information Top
Gene Symbol:MAX ( MGC10775,MGC11225,MGC18164,MGC34679,MGC36767,bHLHd4,bHLHd5,bHLHd6,bHLHd7,bHLHd8,orf1 )
Gene Full Name: MYC associated factor X
Band: 14q23.3
Quick LinksEntrez ID:4149; OMIM: 154950; Uniprot ID:MAX_HUMAN; ENSEMBL ID: ENSG00000125952; HGNC ID: 6913
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst4 / 6231964
fetus35 / 56401262
neonate2 / 3109764
infant0 / 236200 
juvenile2 / 5555635
adult123 / 193912163
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor1 / 3436629
chondrosarcoma8 / 8282396
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor16 / 26384560
glioma8 / 10688374
head and neck tumor10 / 13630273
kidney tumor0 / 689590 
leukemia5 / 9584252
liver tumor3 / 9635931
lung tumor4 / 10312738
lymphoma2 / 7175527
non-neoplasia6 / 9725061
normal197 / 336030758
ovarian tumor7 / 7668291
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer5 / 10268048
retinoblastoma3 / 4635664
skin tumor11 / 12494988
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites5 / 40015124
bladder1 / 2975733
blood7 / 12347856
bone8 / 71655111
bone marrow0 / 488010 
brain56 / 110098950
cervix5 / 48171103
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue17 / 21572278
esophagus2 / 2020998
eye18 / 21105485
heart1 / 8962611
intestine30 / 234472127
kidney8 / 21177737
larynx8 / 24145331
liver3 / 20774314
lung29 / 33697486
lymph1 / 4427022
lymph node3 / 9161032
mammary gland7 / 15327145
mouth2 / 6705229
muscle6 / 10771555
nerve1 / 1576863
ovary8 / 10205178
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate13 / 18934568
salivary gland0 / 201550 
skin16 / 21057475
spleen3 / 5395255
stomach2 / 9661920
testis6 / 33044218
thymus11 / 81131135
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord1 / 1368073
uterus12 / 23287851
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209332_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts345.3
Adipocyte115.65
AdrenalCortex78.6
Adrenalgland150.35
Amygdala314
Appendix73.05
AtrioventricularNode38.2
BDCA4+_DentriticCells598.8
Bonemarrow495.45
BronchialEpithelialCells74.45
CD105+_Endothelial216.15
CD14+_Monocytes768
CD19+_BCells(neg._sel.)802.4
CD33+_Myeloid724.3
CD34+1018.4
CD4+_Tcells918
CD56+_NKCells1049.65
CD71+_EarlyErythroid128.45
CD8+_Tcells880.65
CardiacMyocytes51.35
Caudatenucleus121.8
Cerebellum574.05
CerebellumPeduncles365.9
CiliaryGanglion28.8
CingulateCortex160.95
Colorectaladenocarcinoma165.05
DorsalRootGanglion46.75
FetalThyroid183.15
Fetalbrain296
Fetalliver94.25
Fetallung278.9
GlobusPallidus40.55
Heart389.3
Hypothalamus286.95
Kidney129.8
Leukemia_chronicMyelogenousK-562155.75
Leukemia_promyelocytic-HL-60177.95
Leukemialymphoblastic(MOLT-4)453.25
Liver256.55
Lung793.9
Lymphnode463.75
Lymphoma_burkitts(Daudi)355.7
Lymphoma_burkitts(Raji)451.3
MedullaOblongata138.85
OccipitalLobe136.7
OlfactoryBulb330.25
Ovary41.1
Pancreas88.3
PancreaticIslet167.5
ParietalLobe113.05
Pituitary173.7
Placenta280.1
Pons66.45
PrefrontalCortex479
Prostate892.05
Salivarygland136.3
SkeletalMuscle41.7
Skin58.35
SmoothMuscle200.25
Spinalcord293.95
SubthalamicNucleus71.45
SuperiorCervicalGanglion71.1
TemporalLobe106.4
Testis157.6
TestisGermCell81.95
TestisIntersitial33.1
TestisLeydigCell40.7
TestisSeminiferousTubule47.95
Thalamus121.4
Thymus560
Thyroid592.45
Tongue80.4
Tonsil159
Trachea140.7
TrigeminalGanglion62.2
Uterus711.6
UterusCorpus92.3
WholeBlood1746.6
Wholebrain482.25
colon225.45
pineal_day368.2
pineal_night391.84
retina395.875
small_intestine251.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13795_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.61 ± 0.36
Basal Forebrain8.56 ± 0.24
Basal Part of Pons8.45 ± 0.23
Cerebellar Cortex8.5 ± 0.28
Cerebellar Nuclei8.61 ± 0.33
Claustrum8.73 ± 0.4
Epithalamus8.53 ± 0.3
Frontal Lobe8.28 ± 0.34
Globus Pallidus8.98 ± 0.19
Hypothalamus8.38 ± 0.39
Insula8.24 ± 0.38
Limbic Lobe8.43 ± 0.33
Mesencephalon8.54 ± 0.32
Myelencephalon8.45 ± 0.31
Occipital Lobe8.6 ± 0.31
Parietal Lobe8.46 ± 0.33
Pontine Tegmentum8.36 ± 0.46
Striatum8.5 ± 0.43
Subthalamus8.33 ± 0.19
Temporal Lobe8.36 ± 0.3
Thalamus8.4 ± 0.26
White Matter9.34 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MaxCBCerebellum100
100
MaxCTXCerebral cortex100
100
MaxHIPHippocampal region68.79
100
MaxHPFHippocampal formation91.25
100
MaxHYHypothalamus37.52
33.56
MaxLSXLateral septal complex24.38
18.71
MaxMBMidbrain50.59
47.04
MaxMYMedulla77.35
87.85
MaxOLFOlfactory bulb88.89
86.95
MaxPPons56.46
57.81
MaxPALPallidum48.03
44.91
MaxRHPRetrohippocampal region100
100
MaxsAMYStriatum-like amygdalar nuclei67.85
58.87
MaxSTRStriatum67
55.66
MaxSTRdStriatum dorsal region69.61
58.07
MaxSTRvStriatum ventral region63.84
50.76
MaxTHThalamus50.07
45.02
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MAX_HUMAN_91 10 91 100 QNALLEQQVR PRIDE
PAp00075332 13 78 90 NHTHQQDIDDLKR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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