AutismKB 2.0

Annotation Detail for MCM7


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Basic Information Top
Gene Symbol:MCM7 ( CDC47,MCM2,P1.1-MCM3,P1CDC47,P85MCM,PNAS146 )
Gene Full Name: minichromosome maintenance complex component 7
Band: 7q22.1
Quick LinksEntrez ID:4176; OMIM: 600592; Uniprot ID:MCM7_HUMAN; ENSEMBL ID: ENSG00000166508; HGNC ID: 6950
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body15 / 70761211
blastocyst35 / 62319561
fetus182 / 564012322
neonate33 / 310971061
infant39 / 236201651
juvenile104 / 555561871
adult554 / 1939121285
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor11 / 12794859
bladder carcinoma1 / 1747557
breast (mammary gland) tumor22 / 94178233
cervical tumor27 / 34366785
chondrosarcoma14 / 82823169
colorectal tumor35 / 114246306
esophageal tumor8 / 17290462
gastrointestinal tumor68 / 119369569
germ cell tumor276 / 2638451046
glioma104 / 106883973
head and neck tumor42 / 136302308
kidney tumor32 / 68959464
leukemia60 / 95842626
liver tumor30 / 96359311
lung tumor64 / 103127620
lymphoma70 / 71755975
non-neoplasia11 / 97250113
normal740 / 3360307220
ovarian tumor22 / 76682286
pancreatic tumor22 / 104616210
primitive neuroectodermal tumor of the CNS211 / 1256801678
prostate cancer19 / 102680185
retinoblastoma46 / 46356992
skin tumor75 / 124949600
soft tissue/muscle tissue tumor67 / 125191535
uterine tumor16 / 90257177
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland12 / 33197361
ascites38 / 40015949
bladder7 / 29757235
blood83 / 123478672
bone8 / 71655111
bone marrow26 / 48801532
brain482 / 1100989437
cervix31 / 48171643
connective tissue28 / 149255187
ear0 / 162120 
embryonic tissue66 / 215722305
esophagus9 / 20209445
eye61 / 211054289
heart15 / 89626167
intestine88 / 234472375
kidney69 / 211777325
larynx0 / 241450 
liver53 / 207743255
lung84 / 336974249
lymph60 / 442701355
lymph node18 / 91610196
mammary gland34 / 153271221
mouth31 / 67052462
muscle54 / 107715501
nerve2 / 15768126
ovary27 / 102051264
pancreas23 / 214812107
parathyroid0 / 205390 
pharynx7 / 41328169
pituitary gland1 / 1658560
placenta44 / 280825156
prostate30 / 189345158
salivary gland8 / 20155396
skin118 / 210574560
spleen27 / 53952500
stomach26 / 96619269
testis255 / 330442771
thymus121 / 811311491
thyroid9 / 47473189
tonsil10 / 16999588
trachea7 / 52413133
umbilical cord1 / 1368073
uterus47 / 232878201
vascular16 / 51780308
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208795_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1476.7
Adipocyte25.8
AdrenalCortex33.1
Adrenalgland23.85
Amygdala23.8
Appendix33.1
AtrioventricularNode35.55
BDCA4+_DentriticCells169.65
Bonemarrow94.6
BronchialEpithelialCells57.5
CD105+_Endothelial773.3
CD14+_Monocytes33.5
CD19+_BCells(neg._sel.)123.95
CD33+_Myeloid100.95
CD34+947.45
CD4+_Tcells95.7
CD56+_NKCells123.3
CD71+_EarlyErythroid774.75
CD8+_Tcells78.95
CardiacMyocytes41.15
Caudatenucleus34.1
Cerebellum29.2
CerebellumPeduncles33.45
CiliaryGanglion32.95
CingulateCortex30.25
Colorectaladenocarcinoma1023.45
DorsalRootGanglion25.45
FetalThyroid35.6
Fetalbrain47.65
Fetalliver95.05
Fetallung52
GlobusPallidus23.4
Heart42.35
Hypothalamus39.75
Kidney22.75
Leukemia_chronicMyelogenousK-562311.95
Leukemia_promyelocytic-HL-60179.85
Leukemialymphoblastic(MOLT-4)847.55
Liver41.2
Lung36.65
Lymphnode45.7
Lymphoma_burkitts(Daudi)590.65
Lymphoma_burkitts(Raji)134.85
MedullaOblongata32.1
OccipitalLobe31
OlfactoryBulb26.2
Ovary23.95
Pancreas34.95
PancreaticIslet34.95
ParietalLobe38.25
Pituitary41.4
Placenta49.95
Pons30.75
PrefrontalCortex40.2
Prostate38.1
Salivarygland26.35
SkeletalMuscle36.85
Skin27.9
SmoothMuscle34.55
Spinalcord41.45
SubthalamicNucleus27.55
SuperiorCervicalGanglion41.55
TemporalLobe28.05
Testis140.2
TestisGermCell65.05
TestisIntersitial54.75
TestisLeydigCell54.35
TestisSeminiferousTubule54.5
Thalamus38.3
Thymus353.35
Thyroid41.65
Tongue36.6
Tonsil112.55
Trachea24.3
TrigeminalGanglion32.65
Uterus28.05
UterusCorpus31.3
WholeBlood30.45
Wholebrain25.35
colon62.2
pineal_day45.82
pineal_night41.74
retina42.25
small_intestine67.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P93690
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.88 ± 0.37
Basal Forebrain9.86 ± 0.3
Basal Part of Pons9.3 ± 0.45
Cerebellar Cortex9.42 ± 0.22
Cerebellar Nuclei10.01 ± 0.42
Claustrum9.05 ± 0.4
Epithalamus9.2 ± 0.43
Frontal Lobe9.18 ± 0.56
Globus Pallidus10.79 ± 0.27
Hypothalamus9.15 ± 0.34
Insula8.97 ± 0.25
Limbic Lobe9.01 ± 0.49
Mesencephalon9.55 ± 0.63
Myelencephalon9.43 ± 0.51
Occipital Lobe9.59 ± 0.39
Parietal Lobe9.31 ± 0.43
Pontine Tegmentum9.4 ± 0.4
Striatum9.83 ± 0.65
Subthalamus9.78 ± 0.36
Temporal Lobe9.19 ± 0.39
Thalamus9.68 ± 0.33
White Matter11.12 ± 0.43
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MCM7_HUMAN_121 12 121 132 SPQNQYPAELMR PRIDE
MCM7_HUMAN_252 12 252 263 SITVLVEGENTR PRIDE
MCM7_HUMAN_287 16 287 302 QVVQGLLSETYLEAHR PRIDE
MCM7_HUMAN_500 15 500 514 SLEQNIQLPAALLSR PRIDE
MCM7_HUMAN_546 12 546 557 QPPSQFEPLDMK PRIDE
MCM7_HUMAN_546 15 546 560 QPPSQFEPLDMKLMR PRIDE
MCM7_HUMAN_657 10 657 666 PADVIFATVR PRIDE
PAp00001361 13 482 494 CSILAAANPAYGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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